雅思英语阅读练习题及答案

雅思英语阅读练习题及答案雅思英语阅读练习题及答案雅思英语阅读练习题及答案xxx公司雅思英语阅读练习题及答案文件编号：文件日期：修订次数：第1.0次更改批准审核制定方案设计，管理制度雅思英语阅读练习题及答案：第一篇内容摘要：Thefailureofahigh-profilecholesteroldrughasthrownaspotlightonthecomplicatedmachinerythatregulatescholesterollevels.★Whydidapromisingheartdrugfail?

Doomeddrughighlightscomplicationsofmeddlingwithcholesterol.

1.Thefailureofahigh-profilecholesteroldrughasthrownaspotlightonthecomplicatedmachinerythatregulatescholesterollevels.Butmanyresearchersremainconfidentthatdrugstoboostlevelsof'good'cholesterolarestilloneofthemostpromisingmeanstocombatspirallingheartdisease.2.DrugcompanyPfizerannouncedon2Decemberthatitwascancellingallclinicaltrialsoftorcetrapib,adrugdesignedtoraiseheart-protectivehigh-densitylipoproteins(HDLs).Inatrialof15000patients,asafetyboardfoundthatmorepeoplediedorsufferedcardiovascularproblemsaftertakingthedrugplusacholesterol-loweringstatinthanthoseinacontrolgroupwhotookthestatinalone.3.Thenewscameasakickintheteethtomanycardiologistsbecauseearliertestsinanimalsandpeoplesuggesteditwouldlowerratesofcardiovasculardisease."Therehavebeennoredflagstomyknowledge,"saysJohnChapman,aspecialistinlipoproteinsandatherosclerosisattheNationalInstituteforHealthandMedicalResearch(INSERM)inPariswhohasalsostudiedtorcetrapib."Thiscancellationcameasacompleteshock."4.TorcetrapibisoneofthemostadvancedofanewbreedofdrugsdesignedtoraiselevelsofHDLs,whichferrycholesteroloutofartery-cloggingplaquestotheliverforremovalfromthebody.Specifically,torcetrapibblocksaproteincalledcholesterolestertransferprotein(CETP),whichnormallytransfersthecholesterolfromhigh-densitylipoproteinstolowdensity,plaque-promotingones.Statins,incontrast,mainlyworkbyloweringthe'bad'low-densitylipoproteins.Underpressure5.Researchersarenowtryingtoworkoutwhyandhowthedrugbackfired,somethingthatwillnotbecomeclearuntiltheclinicaldetailsarereleasedbyPfizer.Onehintliesinevidencefromearliertrialsthatitslightlyraisesbloodpressureinsomepatients.Itwasthoughtthatthismildproblemwouldbeoffsetbytheheartbenefitsofthedrug.Butitispossiblethatitactuallyprovedfatalinsomepatientswhoalreadysufferedhighbloodpressure.Ifbloodpressureistheexplanation,itwouldactuallybegoodnewsfordrugdevelopersbecauseitsuggeststhattheproblemsarespecifictothiscompound.OtherprototypedrugsthatarebeingdevelopedtoblockCETPworkinaslightlydifferentwayandmightnotsufferthesamedownfall.6.ButitisalsopossiblethatthewholeideaofblockingCETPisflawed,saysMotiKashyap,whodirectsatherosclerosisresearchattheVAMedicalCenterinLongBeach,California.WhenHDLsexcretecholesterolintheliver,theyactuallyrelyonLDLsforpartofthisprocess.SoinhibitingCETP,whichpreventsthetransferofcholesterolfromHDLtoLDL,mightactuallycauseanabnormalandirreversibleaccumulationofcholesterolinthebody."You'reblockingaphysiologicmechanismtoeliminatecholesterolandeffectivelyconstipatingthepathway,"saysKashyap.

Goingup7.Mostresearchersremainconfidentthatelevatinghighdensitylipoproteinslevelsbyonemeansoranotherisoneofthebestroutesforhelpingheartdiseasepatients.ButHDLsarecomplexandnotentirelyunderstood.Oneapproveddrug,calledniacin,isknowntobothraiseHDLandreducecardiovascularriskbutalsocausesanunpleasantsensationofheatandtingling.Researchersareexploringwhethertheycanbypassthissideeffectandwhetherniacincanlowerdiseaseriskmorethanstatinsalone.Scientistsarealsoworkingonseveralothermeanstobumpuphigh-densitylipoproteinsby,forexample,introducingsyntheticHDLs."Theonlythingweknowisdeadinthewateristorcetrapib,notthewholeideaofraisingHDL,"saysMichaelMiller,directorofpreventivecardiologyattheUniversityofMarylandMedicalCenter,Baltimore.(613wordsnature)Questions1-7Thispassagehas7paragraphs1-7.Choosethecorrectheadingforeachparagraphfromthelistofheadingsbelow.Writethecorrectnumberi-ixinboxes1-7onyouranswersheet.ListofHeadingsi.Howdoestorcetrapibwork?ii.Contradictoryresultpriortothecurrenttrialiii.Onefailuremaypossiblybringaboutfuturesuccessiv.Thefailuredoesn’tleadtototallossofconfidencev.Itistherightroutetofollowvi.Whyit’sstoppedvii.Theymaycombineandtheoreticallyproduceidealresultviii.What’swrongwiththedrugix.ItmightbewrongatthefirstplaceExampleanswerParagraph1iv1．Paragraph2 vi2．Paragraph3 ii3．Paragraph4 vii4．Paragraph5 ix5．Paragraph6 viii6．Paragraph7 ivQuestions7-13Matchtorcetrapib，HDLs，statinandCETPwiththeirfunctions（Questions8-13）..WritethecorrectletterA,B,CorDinboxes8-13onyouranswersheet.NBYoumayuseanylettermorethanonce.7．Ithasbeenadministeredtoover10,000subjectsinaclinicaltrial.8．Itcouldhelpridhumanbodyofcholesterol.9．Researchersareyettofindmoreaboutit.10.Itwasusedtoreducethelevelofcholesterol.11.AccordingtoKashyap,itmightleadtounwantedresultifit’sblocked.12.Itproducedcontradictoryresultsindifferenttrials.13.ItcouldinhibitLDLs.ListofchoicesA.TorcetrapicB.HDLSC.StatinD.CETP(byZhouHong)

SuggestedAnswersandExplanations1．vi2．ii3．vii本段介绍了torcetrapib和statin的治病原理，但是同时短语“incontrast”与之前第二段后半段的内容呼应，暗示了这两种药在理论上能相辅相成，是理想的搭配。第一个选项无法涵盖整段意义，故选择i是错误的。4．iii本段分析了可能导致torcetrapibl临床试验失败的原因，后半段指出如果以上推测正确，那么未来的药物可借鉴这个试验，设法避免torcetrapib的缺陷，研制出有