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PEDIATRICSOVERVIEWCHAPTER1TheScopeofPediatricsPediatricsisconcernedwiththehealthofinfants,children,andadolescents;theirgrowthanddevelopment;andtheiropportunitytoachievefullpotentialasadults.Itisthescienceandartofprevention,diagnosis,andtreatmentofthediseasesofchildrenfrombirththroughadolescence,whetherthesedisturbancesbephysical,mental,oremotional.儿科学是一门关于从出生到青春期儿童疾病预防、诊断与治疗的科学和艺术,这些儿童期的疾病可以是肉体的,也可以是精神方面的。TheScopeofPediatricsThemostcharacteristicfeatureofpediatricsisthatitdealswiththegrowthanddevelopmentofthechild,comprisingallthosechangesinsizeandformandincomplexityoffunctionthatconstitutegrowingup.儿科学最主要的特征是要研究儿童的生长发育,儿童的生长发育造成了其形体方面的变化,也是其功能复杂性的基础。SubspecialtyofPediatricsSubgroupedbytheemphasisofhealthcare:DevelopmentalPediatrics(发育儿科学)PreventivePediatrics(预防儿科学)ClinicalPediatrics(临床儿科学)RehabilitationinPediatrics(儿童康复医学),etcSubgroupedbyage:Perinatology(围生医学)Neonatology(新生儿学)AdolescenceMedicine(青春医学),etcTheGoalOfPediatricsTobecertainofthehealthofchildren.Topromotethelifequalityofchildren.DifferencebetweenChildandAdultAchildisincontinuousgrowthanddevelopment.“ACHILDISNOTALITTLEMAN”Functionsofvariousorgansystems各系统功能差异Degreeofimmunitytodisease机体免疫反应程度Responsetotheeffectsofdisease对疾病的应激反应Dosageofdrugsandtolerancetodrugs对药物剂量及耐受性Mentalandmotorability精神运动的能力Pattenofemotionalresponse心理反应DisparityinOccurrenceandProgressionofDiseasebetweenChildrenandAdultDisparityinanatomy,physiology,andimmunologicfunctionbetweenchildrenandadultTheyounger,themoredifferentDisparityinoccurrenceandprogressionofdiseasebetweenchildrenandadultDisparityinspectrumofdisease不同的疾病谱Congenitalanomalies、inbornerrorsofmetabolism(morecommoninchildren)先天畸形、先天代谢性疾病多见

Newbornsandinfantsisvulnerabletoinfection

新生儿、婴儿易发生感染Sinusitisisrareininfancy鼻窦炎在婴儿相对少见Infantsandyoungchildrenarevulnerabletoobstructioninrespiratorytract婴幼儿易发生气道阻塞DisparityinOccurrenceandProgressionofDiseasebetweenChildrenandAdultDisparityintypeofdiseasePneumoniaChildren:bronchialpneumonia支气管肺泡炎症Adult:lobarpneumonia大叶性肺炎

VitDDeficiencyChildren:rickets(佝偻病)Adult:malacosteon(骨软化)DisparityinoccurrenceandprogressionofdiseasebetweenchildrenandadultDisparityinmanifestationofdiseasediarrheadehydration;feverseizureDisparityinoccurrenceandprogressionofdiseasebetweenchildrenandadultStagesOfAChildByAgeEmbryoperiod(胚胎期):thefirst8weeksofgestation,theformationoftissuesandorgans怀孕~8周Fetusperiod:fromthe9thweekofgestationtothedeliveryoftheneonatalinfant,thegrowthanddevelopmentofthefetus第9周~分娩出生Fetus(胎儿期):fromconceptiontothebirthoftheneonate,40weeks.从受精卵形成~出生为止,40周。Earlyneonates:thefirstweekafterbirthPerinatalperiod(围产期):fromthe28thweek’sofgestationtothe7thdayoftheneonateafterbirth.Neonates(新生儿期):fromdeliveryandcuttingofftheumbilicalcordofthenewborntothe28thdayafterbirth从胎儿娩出脐带结扎时开始~28天Birthinjury,apnea,infections,hemorrhage,hyperbilirubinemia,etcarecommonmedicalproblemsinthisstage.Carefullytakingcareoftheneonatalinfantisofgreatimportance.Infants(婴儿期):the1styearafterbirthInfectiousdiseases,malnutrition,andindigestionarecommoninthisperiod感染、营养不良、消化不良多见Healthcare:Properfeeding合理喂养Vaccinationintime

按时预防接种Youngchild(toddler’sage,幼儿期):from1yearoldto3yearsoldBegintowalk,quicklinguisticandintelligencedevelopment,strongcuriosity学习行走,语言、动作、思维发育迅速,强烈的好奇心

Healthcare:Preventionofaccidentsandinfectiousdiseases防意外、感染Propernutrition合理营养Preschool(学龄前期):from3yearsoldto6~7yearsoldGrowthrateslowsdownbutlanguageandemotion,asindicatorsforintelligence,continuetodevelopquickly.Healthcare:EncouraginggoodbehaviorSuitabletimingtobeginearlyeducationDiseaseprevention:rheumaticfever,acuteglomerulonephritis,etc.Schoolage(学龄期):aged6~7topre-adolescenceSystemandorgansdevelopmenthavebeenalmostreachedtothelevelofadults(exceptforsexualorgans).Self-esteemplaysveryimportantroleinthepsychologicaldevelopment.Healthcare:Encouraginggoodattitudeandhabitsforstudyandbehaviors.Preventionofnearsightedness(近视),decayedteeth(龋齿),etc.Adolescence(earlyyouth,青春期):from10yrsoldto20yrsold.

Theadolescenceofagirlmaybeginandendabout2yrsearlierthanthatofaboy.女孩青春期的开始与结束时间均比男孩的早2年左右。Childreninthisperiodundergorapidchangesinbodysize,shape,physiology,andpsychologicalandsocialfunctioning.ThesecondpeakofphysicalgrowthrateafterbirthHealthcare:nutrition,exercisesandnormalpsychologicaldevelopment.DEVELOPMENTANDFUTUREOFCHILDREN<18yrintotalpopulation developedcountries22.4% developingcountries35.7% china30%(UNCF1999)

<18yr400million(china)InfantMortalityinChinaandDevelopedCountry~1949199920002003City15%1.18%0.55%Ruralarea20%3.7%DevelopedCountries0.4~0.7%yearareaMortalityofChildrenunderAge5inChinaandDevelopedCountry~1949199920002003city2.1%1.4%

0.7%

Ruralarea7.1%4.6%DevelopedCountries0.4~0.8%yearareaTheChangeofMortalityofChildreninChina

MortalityComparisonofChinawithOtherCountriesChildrenaccountforahighpercentageinthetotalpopulation.Inourcountry,thehealthcareofchildrenhasbeeningreatprogression.AnalysisofDeathunderAge5

inChina(2000)Death<5yrs:93%inruralInfantdeath:accountingto80%newborndeath65%oftotalinfantdeath

Leadingdeathcause:Pneumonia(肺炎)、asphyxia(窒息)、prematurity(早产儿)、diarrhea(腹泻)、congenitalanomalies(先天畸形)TheWorldSummitforChildrenin1990“TheWorldDeclarationontheSurvival,ProtectionandDevelopmentofChildreninthe1990s”PlanofActionforImplementingofthedeclaration中国政府制定“九十年代中国儿童发展规划纲要”“(2001~2010)中国儿童发展纲要”“(2011~2020)中国儿童发展纲要”TheChildrenAreOftenAmongtheMostVulnerableorDisadvant-agedinSocietyandTheirNeedsRequireSpecialAttention.PrinciplesandObjectives

《AWorldFitForChildren》-2002PutchildrenfirstEradicatepovertyLeavenochildbehindCareforeverychildEducateeverychildProtectchildrenfromharmandexploitationProtectchildrenfromwarCombatHIV/AIDSListentochildrenandensuretheirparticipationProtecttheEarthforchildrenControlofinfectivediseaseFocusonpsycho-behaviorproblemManagementofAccidenceandinjuryPreventionandtreatmentofcongenitalanomaliesPreventivemeasuresinchildhoodforadultdiseaseTasksofpediatricianin21CenturyReferences:References:KEYPOINTS

INTHISCHAPTERCharacteristicfeaturesofpediatrics

StageofchildrenbyageQuestionAninfantcanmovehisheadfromsidetosidewhilefollowingamovingobject,canlifthisheadfromaproneposition45degreesofftheexaminingtable,smilewhenencouraged,andmakescooingsounds.Hecannotmaintainaseatedposition.Themostlikelyageoftheinfantis1month3months6months9months12monthsThankYouforYourAttention!PEDIATRICSChenDehui(1030412)PediatricDepartmentThefirstAffiliatedHospitalofGuangzhouMedicalUniversityGROWTH

AND

DEVELOPMENTCHAPTER2Assessmentindicatorsforgrowthanddevelopmentaswellastheirmeasure-mentsKeymotorsindicatingforagesofinfantdevelopmentKEYPOINTS

INTHISCHAPTERGrowthAndDevelopmentGrowth

Thechangesofformandincreasesinsizeofthebodyandorgansofachild

儿童各器官、系统的长大DevelopmentMaturationofcells,tissuesandorgans

组织、器官、功能的分化成熟PatternsofGrowthandDevelopmentGrowthanddevelopmentisacontinuousandstagedprocessDifferentrateofdevelopmentinvarioussystemsIndividualvariationingrowthanddevelopmentGrowthanddevelopmentshowCephalocaudalpatternFactorsInfluencing

GrowthAndDevelopmentGenetics基因遗传Nutrition营养状况Healthstatusduringpregnancy母体怀孕时的健康状况Livingenvironments生活环境Effectsofdiseases疾病影响IndicatorsForAssessmentofGrowthAndDevelopmentBodyWeight体重Height身高SittingHeight坐高HeadCircumference头围

ChestCircumferenc

胸围UpperArmCircumference上臂围SubcutaneousFat

皮下脂肪BodyWeightAsensitiveindicatorforgrowthandnutritionalstatus评估生长及营养状况Animportantvariableforcalculationofdrugdosage,energyandfluidsupplement

用于计算儿童用药剂量、能量及液体治疗Examination

Babybalanceforinfants(accuracyin50g),weighingscaleforchildren(accuracyin100g)

婴儿测体重精确:50g;儿童:100gInfantsandchildrenshouldbeweighedwithouttheirclotheson.需要去掉衣服的重量NormalWeightGain

Age NormalBW(kg)Newborn

Male 3.3±0.4 Female 3.2±0.43~4months

Doublebodyweightafterbirth ofbirth1yearold

10 2yearold

12Averagebodyweightforchildrenof1~12old:

BW(kg)=Age(years)×2+8PhysicalWeightLossAnewborn’sweightmaydecrease10%belowbirthweightinthe1stweekasaresultofexcretionofexcessextravascularfluidandpossiblypoorintake.生后1周生理性体重下降,水分丢失、胎粪排出、摄入不足有关,下降约3%~9%Intakeimprovesascolostrumisreplacedbyhigh-fatmilkandtheamountofmilkinfantsuckincrease,Infantshouldregainorexceedbirthweightby7~10daysofageandshouldgrowatapproximately30g/day.

及时喂养,生后7~10天体重恢复出生时体重,后体重增长约30g/天Height

Thelengthfromthetopoftheheadtotheplantapedis测量方法:头顶~平足底部Anparameterforbodygrowthandgrowthvelocity,anassessmentforskeletongrowth

评估儿童生长、生长速度骨骼生长Measurement<3yearsold

Measuringinrecumbentposition

(Bodylength)3岁以下卧位测量>3yearsold

Measuringinstandingposition(Height)BodyLengthScaleBodyLengthScaleNormalHeightGainAgeNormalHeight(cm)GainingHeight(Length)byAgeNewborn503monthsafterbirth11~13cmareincreased

and12~13cmduringthefollowing9

months,soin

the1styeartheheight

willincrease25cm.10~12cminthe2ndyear.Fromage2~10,5~7cm/yearwillbegained.1yearold752yearsold85SomeConceptsAboutHeight

SettingHeight(坐高):Thelengthfromthetopofheadtoischialtuberositywhichmeansthelengthoftheheadandspinalcolumn头顶部~坐骨结节的距离UpperLength(上部量):Thelengthfromthetopofheadtotheupperedgeofsymphysispubis头顶部~耻骨联合上缘的距离,评估扁骨的生长LowerLength(下部量):Thelengthfromtheupperedgeofsymphysispubistodorsaldecubitus.耻骨联合上缘~脚底,评估长骨的生长。UpperLength&LowerLength新生儿的上部量占身长的60%,下部量占身长的40%,12岁以前各年龄期有一定的比例。对矮小症患儿,除测量身长外,尚需测量上、下部量,如下部量过短表示长骨发育障碍,见于克汀病(甲状腺功能低下)及软骨营养障碍。

Head/Trunk+legUpperlengthinbodylengthMidpointLowerlengthinbodylengthNewborn1/460%Abovenavel40%Age2BelownavelAge6Betweennaveland

theupperedgeofsymphysispubisAge1250%theupperedgeofsymphysispubis50%Adult1/8Lowerlength>UpperlengthHeadCircumference&

ChestCircumferenceHeadCircumference(头围):Indicatorforgrowthanddevelopmentofbrainandcranium

评估脑与颅骨的发育。出生时约33~34cm,1岁时46cm,2岁时48cm。ChestCircumference(胸围):Indicatorforgrowthanddevelopmentofthoraxandlung.评估肺与胸廓的生长。出生胸围约32cm,1岁时约等于头围。1岁~青春前期胸围=头围+年龄-1cmHeadCircumferenceMeasurementMeasuringthegrea-testoccipitofrontalcircumference眉弓上缘、枕骨结节环绕一周的长度Reflectingthevolumeofintracranialcon-tentsaswellasthethicknessoftheskullandscalpChestCircumferenceExaminationMeasuringthethoraciccirclearoundnipplesandinferiorangleofscapulaandtakingtheaveragevaluebetweeninspirationandexpiration平乳头下缘经肩胛骨下缘平绕胸一周NormalValuesofHeadCircumference&

ChestCircumferenceAge

HC(cm)

CC(cm)

HC-CC(cm)

Newborn 32~34 32 <1~21yearold 46 46

01yearlater 48(age2) HC+(age-1)

>(age-1)HC:Duringthe1st3monthsoflifeHCwillincreaseabout6cmwhichwilltheamountofincreaseduringthefollowing9.HCgrowsabout6~7cmfromage2to15.GrowthCurveofHeadCircumference

&

ChestCircumference(cm)年龄AgeHCCCAssessmentofGrowthASSESSMENTOFGROWTH均值(Mean)&标准差Standard(SD)正常分布±1SD+2SD+3SD68.3%95.4%99.7%ASSESSMENTOFGROWTH百分位数(Percentile)P3~P9795%表格与生长曲线(Growthchart)多参数指标年龄别体重(Weightforage)年龄别身高(Heightforage)体重别身高(Weightforheight)Developments

ofSkeletonandTeethCranialBonesThematureofcranialbones(颅骨)canbereflectedby:Headcircumference头围Fontanel囟门Closingofsuture骨缝闭合Bone,Fontanels,SuturesOfCranialFrontalboneOccipitalboneParietalboneNormalFusionofCranialBonesPosteriorfontanel(后囟门):6~8wksafterbirth出生时很小或已闭合,6~8周闭合Suturesofcranialbones(颅骨缝):3~4monthsafterbirthAnteriorfontanel(前囟门):1~2cminnewborn,Theanteriorfontanelusuallytendstoenlargeduringthefirstfewmonthsoflife,lessenafter6monthsold.Itclosescompletelyin1~1.5yearsold.出生时1~2cm,1~1.5岁闭合SpinalColumn正常情况Duringthefirstyearoflife,spinalgrowupfasterthanextremities.Lateron,thesituationisreversed.新生儿的脊柱弯曲不明显,呈轻度后凸,3个月的婴儿能抬头时出现凸向前的颈曲,6个月后会坐时,出现凸向后的胸曲,1岁开始走路时,出现凸向前的腰曲。OssificationCenter

骨化中心Theappearanceofossificationcenter(endochondralossification)isoneofthemarksforskeletal.长骨的生长主要由长骨干骺端的软骨骨化,骨膜下成骨,使长骨长长、增粗,当骨骺与骨干融合时,标志长骨停止生长。骨化中心的出现评估长骨的生长成熟程度。BoneAge骨龄Boneageisthemeasurementofskeletalmatura-tion.AradiographofthelefthandandwristisobtainedandcomparedwiththepublishedstandardsofGreulichandPyle.Kneefilmsaresometimesaddedforyoungerchildren.

用X线检查测定不同年龄儿童长骨干骺端骨化中心的出现时间、数目、形态的变化,并标准化,为骨龄。BoneAge骨龄Referencestandardsforbonematurationfacilitateestimationofboneage.

骨龄反映长骨的生长成熟程度

Theboneageislowandiscomparabletotheheightage:Constitutionalgrowthdelay,Endocrinologicshortstature,Undernutrition.

骨龄延迟:生长发育迟缓,生长激素缺乏症,营养不良等Theboneageisnormal(comparedtochronologicalage):Familialshortstature.

骨龄正常:家族性身材矮小DevelopmentofOssificationCenters腕骨骨化中心的出现时间

年龄 骨化中心

3M

头骨、钩骨1岁下桡骨

2~3岁 三角骨

3岁 月骨3.5~5岁

大、小多角骨

5~6岁 舟状骨

7~9岁

豆状骨骨龄测定在临床上有重要意义,骨龄落后见于生长激素缺乏症、呆小病、肾小管酸中毒等;骨龄超前见于中枢性性早熟、先天性肾上腺皮质增生症等。3月头、钩骨;1岁下桡骨(够);加了2与3(三角骨)等约(月骨)多少?答案:大小多(骨)3-5岁周(舟)5舟6下尺骨(6-7岁);逗9豆10全都齐DentitionPrimarydentition(乳牙)Timeoferuptionofprimaryteeth:About6months(4~10months)

ofage,allprimaryteethshouldbeeruptedat2~2.5yearsoldNumberofprimaryteeth:20intotalCalculationoferuptionofprimaryteeth:Numberofprimaryteeth=Age(month)-6TimeAndOrderofDentitionDentitionPermanentteethTimeofgrowingpermanentteethBeginning:at6~7yearsoldFinish:at20~30yearsoldNum

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