Toll-like-receptor-modulator - Toll-like Receptor (TLR) Modulator - 生命科学试剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEToll-like receptor modulatorCat. No.: HY-10018CAS No.: 926927-42-6分式: CHFNO分量: 348.27作靶点: Toll-like Receptor (TLR)作通路: Immunology/Inflammation储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO :

2、 100 mg/mL (287.13 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.8713 mL 14.3567 mL 28.7134 mL5 mM 0.5743 mL 2.8713 mL 5.7427 mL10 mM 0.2871 mL 1.4357 mL 2.8713 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次

3、添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 3.5 mg/mL (10.05 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 3.5 mg/mL (10.05 mM); Clear solution3. 请依序添加每种溶剂： 1

4、0% DMSO 90% corn oil1/2 Master of Small Molecules 您边的抑制剂师www.MedChemESolubility: 3.5 mg/mL (10.05 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Toll-like receptor modulator种 TLR7/8 调节剂，能够调节免疫功能。IC50 & Target TLR7/8 1体外研究 Toll-like receptor modulator (Compound 7) is a modulator of TLR7/8, which modulates immune function 1.REFERENCES1. Doherty, George A, et al. 8-substituted benzoazepines as toll-like receptor modulators. US 8153622 B2.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>