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OutlinesGeneralconsiderationsHistoricalperspectiveAnatomyPathophysiologyClinicalfindingsDiagnosisTreatment1急性阑尾炎英文1/1/2023OutlinesGeneralconsiderations1GeneralconsiderationsAbout8%ofpeopleinWesterncountrieshaveappendicitisatsometimeduringtheirlife,withapeakincidencebetween10and30yearsofage.Acuteappendicitisisthemostcommongeneralsurgicalemergency.(10%)2急性阑尾炎英文1/1/2023GeneralconsiderationsAbout8%2GeneralconsiderationsAcuteappendicitishasproteanmanifestations.Itmaysimulatealmostanyotheracuteabdominalillnessandinturnmaybemimickedbyavarietyofconditions.Progressionofsymptomsandsignsistherule—incontrasttothefluctuatingcourseofsomeotherdiseases.3急性阑尾炎英文1/1/2023GeneralconsiderationsAcuteap3Historicalperspective
WillardPackardperformedthefirstsurgeryin1867.In1886,ReginaldFitzdescribedthecharacteristic,clinicalfindingsandpathologyofthedisease,identifiedtheappendixastheprimarycauseofrightlowerquadrantinflammation.Fitzcoinedthetermappendicitisandrecommendedearlysurgicaltreatment4急性阑尾炎英文1/1/2023HistoricalperspectiveWillard4HistoricalperspectiveIn1889,ChesterMcBurneydescribedcharacteristicmigratorypainaswellaslocalizationofthepainalonganobliquelinefromtheanteriorsuperioriliacspinetotheumbilicus.In1894,McBurney
describedarightlowerquadrantmuscle-splittingincisionforremovaloftheappendix.5急性阑尾炎英文1/1/2023HistoricalperspectiveIn1889,5HistoricalperspectiveInthe1940s,themortalityratefromappendicitisimprovedwiththewidespreaduseofbroad-spectrumantibiotics.In1982,LaparoscopicappendectomywasfirstreportedbythegynecologistKurtSemmbuthasonlygainedwidespreadacceptanceinrecentyears.6急性阑尾炎英文1/1/2023HistoricalperspectiveInthe167急性阑尾炎英文1/1/20237急性阑尾炎英文12/28/20227Anatomy&physiologyThebaseoftheappendixislocatedattheconvergenceofthetaeniae(3)ofcolon.Thisanatomicrelationshipfacilitatesidentificationandlocationoftheappendixatoperation.8急性阑尾炎英文1/1/2023Anatomy&physiologyThebaseo89急性阑尾炎英文1/1/20239急性阑尾炎英文12/28/2022910急性阑尾炎英文1/1/202310急性阑尾炎英文12/28/202210Pathophysiology
Obstructionofthelumenisbelievedtobethemajorcauseofacuteappendicitis.Thismaybeduetolymphoidhyperplasia,inspissatedstool,fecalith,vegetablematterorseeds,parasites,oraneoplasm.11急性阑尾炎英文1/1/2023PathophysiologyObstructionof11PathophysiologyObstructionoftheappendiceallumenBacterialovergrowthContinuedsecretionofmucusIntraluminaldistentionandincreasedwallpressure12急性阑尾炎英文1/1/2023PathophysiologyObstructionof12PathophysiologySubsequentimpairmentoflymphaticandvenousdrainagemucosalischemiaThesefindingsincombinationpromotealocalizedinflammatoryprocessthatmayprogresstogangreneandperforation.13急性阑尾炎英文1/1/2023PathophysiologySubsequentimpa13PathophysiologyInflammationoftheadjacentperitoneumgivesrisetolocalizedpainintherightlowerquadrant.Perforationtypicallyoccursafteratleast48hoursfromtheonsetofsymptomsandisaccompaniedbyanabscesscavitywalled-offbythesmallintestineandomentum.14急性阑尾炎英文1/1/2023PathophysiologyInflammationof14Clinicalfindings
Clinicalfindings
15急性阑尾炎英文1/1/2023Clinicalfindings
Clinicalfin15historyandsymptomAppendicitisneedstobeconsideredinthedifferentialdiagnosisofnearlyeverypatientwithacuteabdominalpainThetypicalpresentationbeginswithvagueperi-umbilicalpainfollowedbyanorexia,nauseaandvomiting.Thenlocalizestotherightlowerquadrant.16急性阑尾炎英文1/1/2023historyandsymptomAppendiciti16
historyandsymptomTheclassicpatternofmigratorypainisthemostreliablesymptomofacuteappendicitisFeverensues,followedbythedevelopmentofleukocytosisOccasionalpatientshaveurinarysymptomsormicroscopichematuria17急性阑尾炎英文1/1/2023
historyandsymptomTheclassi17migratorypain18急性阑尾炎英文1/1/2023migratorypain18急性阑尾炎英文12/28/218PhysicalExaminationLow-gradefeveriscommon(~38℃).DiminishedbowelsoundsFocaltenderness(commonlyatMcBurney‘spoint)------locatedonethirdofthedistancealongalinedrawnfromtheanteriorsuperioriliacspinetotheumbilicus
ReboundtendernessVoluntaryguarding19急性阑尾炎英文1/1/2023PhysicalExaminationLow-grade19PhysicalExaminationDunphy'ssign---coughingcauseincreasedpainRovsing'ssign
---painintherightlowerquadrantduringpalpationoftheleftlowerquadrant20急性阑尾炎英文1/1/2023PhysicalExaminationDunphy'ss20PhysicalExaminationPsoassign---painonextensionoftherighthip(retrocecalappendix)Obturatorsign---painoninternalrotationofthehip(pelvicappendix)21急性阑尾炎英文1/1/2023PhysicalExaminationPsoassign21LaboratoryStudiesTheaverageleukocytecountis15*109/L,and90%ofpatienthavecountover10*109/LMorethan75%neutrophilsin¾ofpatients.Acompletelynormalleukocytecountanddifferentialisfoundinabout10%ofpatients.22急性阑尾炎英文1/1/2023LaboratoryStudiesTheaverage22
ImagingstudiesPlainabdominalfilms:maybeusefulforthedetectionofureteralcalculi,smallbowelobstruction,orperforatedulcer,butsuchconditionsarerarelyconfusedwithappendicitis.UltrasonographyandCTscan:behelpfulinpatientswithatypicalsymptoms,suchaschildrenandelderlyperson.23急性阑尾炎英文1/1/2023ImagingstudiesPlainabdomina2324急性阑尾炎英文1/1/202324急性阑尾炎英文12/28/202224A,CTscanoftheabdomendemonstratesanedematous,thickenedappendix(arrow)withobstructingappendicolith(arrowhead).B,CTscanofabdomendemonstratesaperforatedappendixwithacomplexabscessandpelvicfluidcollection(arrow).BL,bladder;UT,uterus.25急性阑尾炎英文1/1/2023A,CTscanoftheabdomendemo25EssentialsofdiagnosisAbdominalmigratorypainAnorexia,nauseaandvomitingLocalizedabdominaltendernessLow-gradefeverLeukocytosis26急性阑尾炎英文1/1/2023EssentialsofdiagnosisAbdomin26DifferentialDiagnosesSometimes,thediagnosisofappendicitismaybedifficult.Mesentericlymphadenitis,gastrointestinalulcerperforationMeckel’sdiverticulitis,ectopicpregnancy,pelvicinflammatorydisease27急性阑尾炎英文1/1/2023DifferentialDiagnosesSometime27Specialcategoryofappendicitisininfants,inchildren,inwemenduringpregnancy,inelderlypeopleinpatientsinfectedwithHIV28急性阑尾炎英文1/1/2023Specialcategoryofappendicit28ComplicationPerforationPeritonitisAppendicealabscesspylephlebitis29急性阑尾炎英文1/1/2023ComplicationPerforation29急性阑尾炎29TreatmentSurgicaltreatment:Mostpatientswithacuteappendicitisaremanagedbypromptsurgicalremovaloftheappendix.(Appendectomy)Non-surgicaltreatment:EarlyStage,Objectiveconditionsarenotallowed,Seriousorganicdisease.(antibiotics)30急性阑尾炎英文1/1/2023TreatmentSurgicaltreatment:3031急性阑尾炎英文1/1/202331急性阑尾炎英文12/28/20223132急性阑尾炎英文1/1/202332急性阑尾炎英文12/28/20223233急性阑尾炎英文1/1/202333急性阑尾炎英文12/28/202233TreatmentLaparoscopicappendectomyofferstheadvantageof:diagnosticlaparoscopyshorterrecoverylessconspicuous
incisions34急性阑尾炎英文1/1/2023TreatmentLaparoscopicappendec34SubjectivetothinkWhat’stheEssentialsofdiagnosisaboutacuteappendicitis?35急性阑尾炎英文1/1/2023SubjectivetothinkWhat’sthe35OutlinesGeneralconsiderationsHistoricalperspectiveAnatomyPathophysiologyClinicalfindingsDiagnosisTreatment36急性阑尾炎英文1/1/2023OutlinesGeneralconsiderations36GeneralconsiderationsAbout8%ofpeopleinWesterncountrieshaveappendicitisatsometimeduringtheirlife,withapeakincidencebetween10and30yearsofage.Acuteappendicitisisthemostcommongeneralsurgicalemergency.(10%)37急性阑尾炎英文1/1/2023GeneralconsiderationsAbout8%37GeneralconsiderationsAcuteappendicitishasproteanmanifestations.Itmaysimulatealmostanyotheracuteabdominalillnessandinturnmaybemimickedbyavarietyofconditions.Progressionofsymptomsandsignsistherule—incontrasttothefluctuatingcourseofsomeotherdiseases.38急性阑尾炎英文1/1/2023GeneralconsiderationsAcuteap38Historicalperspective
WillardPackardperformedthefirstsurgeryin1867.In1886,ReginaldFitzdescribedthecharacteristic,clinicalfindingsandpathologyofthedisease,identifiedtheappendixastheprimarycauseofrightlowerquadrantinflammation.Fitzcoinedthetermappendicitisandrecommendedearlysurgicaltreatment39急性阑尾炎英文1/1/2023HistoricalperspectiveWillard39HistoricalperspectiveIn1889,ChesterMcBurneydescribedcharacteristicmigratorypainaswellaslocalizationofthepainalonganobliquelinefromtheanteriorsuperioriliacspinetotheumbilicus.In1894,McBurney
describedarightlowerquadrantmuscle-splittingincisionforremovaloftheappendix.40急性阑尾炎英文1/1/2023HistoricalperspectiveIn1889,40HistoricalperspectiveInthe1940s,themortalityratefromappendicitisimprovedwiththewidespreaduseofbroad-spectrumantibiotics.In1982,LaparoscopicappendectomywasfirstreportedbythegynecologistKurtSemmbuthasonlygainedwidespreadacceptanceinrecentyears.41急性阑尾炎英文1/1/2023HistoricalperspectiveInthe14142急性阑尾炎英文1/1/20237急性阑尾炎英文12/28/202242Anatomy&physiologyThebaseoftheappendixislocatedattheconvergenceofthetaeniae(3)ofcolon.Thisanatomicrelationshipfacilitatesidentificationandlocationoftheappendixatoperation.43急性阑尾炎英文1/1/2023Anatomy&physiologyThebaseo4344急性阑尾炎英文1/1/20239急性阑尾炎英文12/28/20224445急性阑尾炎英文1/1/202310急性阑尾炎英文12/28/202245Pathophysiology
Obstructionofthelumenisbelievedtobethemajorcauseofacuteappendicitis.Thismaybeduetolymphoidhyperplasia,inspissatedstool,fecalith,vegetablematterorseeds,parasites,oraneoplasm.46急性阑尾炎英文1/1/2023PathophysiologyObstructionof46PathophysiologyObstructionoftheappendiceallumenBacterialovergrowthContinuedsecretionofmucusIntraluminaldistentionandincreasedwallpressure47急性阑尾炎英文1/1/2023PathophysiologyObstructionof47PathophysiologySubsequentimpairmentoflymphaticandvenousdrainagemucosalischemiaThesefindingsincombinationpromotealocalizedinflammatoryprocessthatmayprogresstogangreneandperforation.48急性阑尾炎英文1/1/2023PathophysiologySubsequentimpa48PathophysiologyInflammationoftheadjacentperitoneumgivesrisetolocalizedpainintherightlowerquadrant.Perforationtypicallyoccursafteratleast48hoursfromtheonsetofsymptomsandisaccompaniedbyanabscesscavitywalled-offbythesmallintestineandomentum.49急性阑尾炎英文1/1/2023PathophysiologyInflammationof49Clinicalfindings
Clinicalfindings
50急性阑尾炎英文1/1/2023Clinicalfindings
Clinicalfin50historyandsymptomAppendicitisneedstobeconsideredinthedifferentialdiagnosisofnearlyeverypatientwithacuteabdominalpainThetypicalpresentationbeginswithvagueperi-umbilicalpainfollowedbyanorexia,nauseaandvomiting.Thenlocalizestotherightlowerquadrant.51急性阑尾炎英文1/1/2023historyandsymptomAppendiciti51
historyandsymptomTheclassicpatternofmigratorypainisthemostreliablesymptomofacuteappendicitisFeverensues,followedbythedevelopmentofleukocytosisOccasionalpatientshaveurinarysymptomsormicroscopichematuria52急性阑尾炎英文1/1/2023
historyandsymptomTheclassi52migratorypain53急性阑尾炎英文1/1/2023migratorypain18急性阑尾炎英文12/28/253PhysicalExaminationLow-gradefeveriscommon(~38℃).DiminishedbowelsoundsFocaltenderness(commonlyatMcBurney‘spoint)------locatedonethirdofthedistancealongalinedrawnfromtheanteriorsuperioriliacspinetotheumbilicus
ReboundtendernessVoluntaryguarding54急性阑尾炎英文1/1/2023PhysicalExaminationLow-grade54PhysicalExaminationDunphy'ssign---coughingcauseincreasedpainRovsing'ssign
---painintherightlowerquadrantduringpalpationoftheleftlowerquadrant55急性阑尾炎英文1/1/2023PhysicalExaminationDunphy'ss55PhysicalExaminationPsoassign---painonextensionoftherighthip(retrocecalappendix)Obturatorsign---painoninternalrotationofthehip(pelvicappendix)56急性阑尾炎英文1/1/2023PhysicalExaminationPsoassign56LaboratoryStudiesTheaverageleukocytecountis15*109/L,and90%ofpatienthavecountover10*109/LMorethan75%neutrophilsin¾ofpatients.Acompletelynormalleukocytecountanddifferentialisfoundinabout10%ofpatients.57急性阑尾炎英文1/1/2023LaboratoryStudiesTheaverage57
ImagingstudiesPlainabdominalfilms:maybeusefulforthedetectionofureteralcalculi,smallbowelobstruction,orperforatedulcer,butsuchconditionsarerarelyconfusedwithappendicitis.UltrasonographyandCTscan:behelpfulinpatientswithatypicalsymptoms,suchaschildrenandelderlyperson.58急性阑尾炎英文1/1/2023ImagingstudiesPlainabdomina5859急性阑尾炎英文1/1/202324急性阑尾炎英文12/28/202259A,CTscanoftheabdomendemonstratesanedematous,thickenedappendix(arrow)withobstructingappendicolith(arrowhead).B,CTscanofabdomendemonstratesaperforatedappendixwithacomplexabscessandpelvicfluidcollection(arrow).BL,bladder;UT,uterus.60急性阑尾炎英文1/1/2023A,CTscanoftheabdomendemo60EssentialsofdiagnosisAbdominalmig
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