AV-105-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEAV-105Cat. No.: HY-120947CAS No.: 1205550-99-7分式: CHNOS分量: 612.73作靶点: Others作通路: Others储存式: Pure form -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 62.5 mg/mL (102.00 mM; Need ultrasonic)Mass Solvent

2、1 mg 5 mg 10 mg Concentration制备储备液1 mM 1.6320 mL 8.1602 mL 16.3204 mL5 mM 0.3264 mL 1.6320 mL 3.2641 mL10 mM 0.1632 mL 0.8160 mL 1.6320 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 AV-105种 Florbetapir (18F)-放射性标记的 slyrylpyridine 磺酸酯前体。AV-105 可以合成 18F-放射性标记的化合物，可于脑神经退性疾病的正电发射断

3、层扫描 (PET) 成像。体外研究 The AV-105 synthesis method utilizes a primary tosylate instead of a primary mesylate as an active leavinggroup. Use of the tosylate precursor for radiofluorination is beneficial, at least for the reason that the tosylategenerated during the radiofluorination reaction is readily re

4、moved by chromatographic means from the 18F-radiolabeled imaging product 1.1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEREFERENCES1. Tyler Benedum, et al. Synthesis of 18f-radiolabeled styrylpyridines from tosylate precursors and stable pharmaceutical compositionsthereof. WO2010078370A1.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: