TCS-359 - FLT3 抑制剂 - 生命科学试剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemETCS 359Cat. No.: HY-13907CAS No.: 301305-73-7分式: CHNOS分量: 360.43作靶点: FLT3作通路: Protein Tyrosine Kinase/RTK储存式: 4C, protect from light* In solvent : -80C, 6 months; -20C, 1 month (protect fromlight)溶解性数据体外实验 DMSO : 14.29 mg/mL (39

2、.65 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.7745 mL 13.8723 mL 27.7446 mL5 mM 0.5549 mL 2.7745 mL 5.5489 mL10 mM 0.2774 mL 1.3872 mL 2.7745 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；

3、澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 1.43 mg/mL (3.97 mM); Suspended solution; Need ultrasonic2. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 1.43 mg/mL (3.97 mM); Clear solutionBIOLOGICAL ACTIVITY1/2 Master of Small Molecu

4、les 您边的抑制剂师www.MedChemE物活性 TCS 359是FLT3抑制剂，IC50为42 nM。户使本产品发表的科研献 Oncotarget. 2016 May 17;7(20):29131-42.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Patch RJ, et al. Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg Med Chem Lett. 2006 Jun15;16(12):3282-6.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: