多发性骨髓瘤化疗方案

..word.zl-..word.zl-化疗方案骨髓瘤方案药物剂量用法时间ABVD每28天一周期阿霉素25mg/m2ivd1，15博来霉素10mg/m2ivd1，15XX碱6mg/m2ivd1，15达卡巴嗪375mg/m2ivd1，15BACOP（*为加强方案）阿霉素25mg/m2(*40mg/m2)或ivd1，8每28天一周期EPI40mg/m2(*50mg/m2)环磷酰胺650mg/m2ivd1，8XX新碱1.4mg/m2ivd1，8泼尼松40-60mg/m2pod15-28博来霉素10mg/m2ivd15，22BEACOPP（*为加强方案）阿霉素25mg/m2(*35mg/m2)ivd1每21天一周期环磷酰胺650mg/m2(*1250mg/m2)ivd1依托泊苷100mg/m2(*200mg/m2)ivd1-3XX新碱1.4mg/m2(max2mg/m2)ivd8甲基苄肼100mg/m2pod1-7泼尼松40mg/m2pod1-14

博来霉素10mg/m2ivd8dex-DEAM卡莫司汀60mg/m2ivd2美法仑20mg/m2ivd3依托泊苷200mg/m2iv，Q12hd4-7阿糖胞苷100mg/m2iv，Q12hd4-7地塞米松8mgpo，tidd1-10mini-DEAM卡莫司汀60mg/m2ivd1美法仑30mg/m2（max50mg）ivd5依托泊苷75mg/m2ivd2-5阿糖胞苷100mg/m2iv，Q12hd2-5CHOP14天或21天一阿霉素50mg/m2（或EPIivd1周期环磷酰胺80mg/m2）ivd1XX新碱750mg/m2ivd1泼尼松1.4mg/m2pod1-5CHOP-E100mg每21天一周期阿霉素ivd1环磷酰胺50mg/m2（或EPIivd1XX新碱80mg/m2）ivd1依托泊苷750mg/m2ivd1-3

泼尼松1.4mg/m2Pod1-5CHOP-L-ASP100mg/m2每21天一周期阿霉素100mgivd1环磷酰胺ivd1XX新碱50mg/m2(或EPIivd1泼尼松80mg/m2)pod1-5左旋门冬750mg/m2ivd1,3,7,9,11酰胺酶1.4mg/m2(max2mg)CEOP100mg每21天一周期环磷酰胺6000U/ivd1依托泊苷ivd1XX新碱ivd1泼尼松500mg/m2pod1-5COP37.5mg/m2每14-21天一周环磷酰胺2mgivd1期XX新碱75mg/m2ivd1，8泼尼松pod1-5COPP750mg/m2每28天一周期环磷酰胺1.4mg/m2(max2mg)ivd1，8XX新碱100mgivd1，8丙卡巴肼pod1-14泼尼松600-800mgpod1-14

每21天一周期环磷酰胺100mg/m2ivd1-5XX新碱40mg/m2ivd1泼尼松pod1-5DDP-VP-16400mg/m2每21天一周期顺铂1.4（max2mg）ivd1-3（水100mg化）依托泊苷ivd5-10DHAP30mg/m2每14-21天一周顺铂ivd1期阿糖胞苷40-50mg/m2iv，Q12hd2地塞米松ivd1-4DICE100mg/m2每21天一周期异环磷酰2g/m2ivd1-4胺40mg顺铂ivd1-4依托泊苷1000mg/m2ivd1-4地塞米松pod1-10EPOCH25mg/m2每21天一周期阿霉素60mg/m2iv（连续d1-46-9mg/m296h）依托泊苷iv（连续d1-4CVP1.4mg/m2（max2mg）

10mg/m296h)XX新碱iv（连续d1-450mg/m296h)环磷酰胺ivd5泼尼松0.4mg/m2Pod1-5EPOCH每21天一周期依托泊苷750mg/m2ivd1-4顺铂60mg/m2iv（连续d1-496h)甲泼尼龙60mg/m2ivd1-4阿糖胞苷25mg/m2ivd5FC每28天一周期氟达拉滨500mg/m2ivd1-3环磷酰胺2g/m2ivd1-3FCM每28天一周期氟达拉滨25-30mg/m2ivd1-3米托蒽醌250-300mg/m2ivd1环磷酰胺ivd1-3FCM25mg/m2每28天一周期氟达拉滨6-8mg/m2ivd1-3米托蒽醌200mg/m2ivd1地塞米松iv/pod1-5

每21天一周期吉西他滨10mg/m2ivd1，8顺铂20mgivd1地塞米松ivd1-4GemOx1000mg/m2吉西他滨75mg/m2ivd1奥沙利铂40mgivd1ICE依托泊苷1000mg/m2ivd1-3异环磷酰100mg/m2iv（24h胺输注）d2卡铂100mg/m2ivd2IVE5000mg/m2每21天一周期表阿霉素ivd1异环磷酰按AUC=5,max800mgiv（22h）d1-3胺依托泊苷50mg/m2iv（＞2h）d1-3MACOP-B3000mg/m2每12周重复一阿霉素ivwk1,3,5,7,9,周期200mg/m211环磷酰胺ivwk1,3,5,7,9,50mg/m211GDP25mg/m2

XX新碱ivwk2,4,6,8,1350mg/m20,12博来霉素ivwk4,8,12泼尼松1.4mg/m2（max2mg）powk1-11后逐渐减量10mg/m2wk2,6,10MIME75mg/dMethy-ivd1guazone异环磷酰ivd1-5胺500mg/m2依托泊苷ivd1-3甲氨蝶呤1000mg/m2ivd3MOEP每21天一周期米托蒽醌100mg/m2ivd1-3XX新碱30mg/m2ivd1依托泊苷ivd1-5（7）泼尼松10mgpod1-5（7）MOPP1.4mg/m2（max2mg）每28天一周期氮芥100mgivd1，8XX新碱60mgivd1，8丙卡巴肼pod1-14

泼尼松6mg/m2pod1-14SMILE1.4mg/m2每28天一周期甲氨蝶呤100mg/m2ivd1异环磷酰40mg/m2ivd2-4胺依托泊苷2g/m2ivd2-4地塞米松1500mg/m2ivd2-4L-ASPivd8,10,12,14,100mg/m216,18,20HD-MTX40mg/m2甲氨蝶呤6000U/m2iv（12h）d1HD-AraC阿糖胞苷iv，Q12hd1-3（6）ABCM1-3g阿霉素ivd1卡莫司汀3g/m2ivd1环磷酰胺pod22-25美法仑30mg/m2pod22-25DCEP30mg/m2地塞米松100mg/m2Iv/pod1-4环磷酰胺6mg/m2iv,持续d1-4依托泊苷iv,持续d1-4

顺铂40mg/div,持续d1-4DT-PACE400mg/m2地塞米松40mg/m2iv/pod1-4沙利度胺10mg/m2po维持阿霉素Ivd1-4顺铂40mg/div,持续d1-4环磷酰胺400mg/div,持续d1-4依托泊苷10mg/m2iv,持续d1-4MP10mg/m2每4-6周一周期美法仑400mg/m2pod1-4泼尼松40mg/m2pod1-4M2美法仑10mg/m2pod1-4卡莫司汀50mg/m2ivd1环磷酰胺ivd1XX新碱8mg/m2ivd1泼尼松20mg/m2pod1-7,8-14PEDA400mg/m2顺铂1.2mg/m2ivd1-4依托泊苷40mg/m2,20mg/m2ivd1-4地塞米松ivd1-5阿糖胞苷20mg/m2ivd5

XX新碱40mg/divd1-4阿霉素1g/m2ivd1-4地塞米松pod1-4，0.4mg/m29-12,17-20LD9mg/m2雷利度胺40mgpod1-21地塞米松iv/pod1-4,9-12,17-20LR25mg/d雷利度胺40mg/dpo每月wks1-3利妥昔单ivwks2-5,13-1抗25mg/d6L+DVD雷利度胺375mg/m2pod1-21脂质体阿ivd1霉素XX新碱10mg/divd1地塞米松40mg/m2pod1-4L+MP雷利度胺2mgpod1-21VAD100mg/m2

美法仑40mg/dpod1-4泼尼松pod1-4CTD5-10mg/d沙利度胺0.18-0.25mg/kg/dpod1-28环磷酰胺2mg/kg/dpod1-21地塞米松pod1-4,15-21MPT200mg沙利度胺50mg/d,bidpod1-28美法仑50mg/d,Qodpod1-7泼尼松pod1-7TD100mg/d沙利度胺4mg/m2pod1-28地塞米松40mg/m2pod1-4,9-12,17-20（奇数200mg/d周期）40mg/dpod1-4（偶数周期）TDD沙利度胺40mg/dpod1-28脂质体阿ivd1霉素地塞米松100mg/dpod1-4,9-12,140mg/d 40mg/d 第2-4周..word.zl-40mg/m40mg/m2 7-20..word.zl-TP沙利度胺泼尼松40mg/dpopoQdQodVD硼替佐米200mg/divd1,4,8,11地塞米松50mgivd1-4,9-12,17-20（奇数1.3mg/m2周期）40mg/dd1-4（偶数周期）VMP硼替佐米ivd1,4,8,11,22,25,29,32美法仑ivd1-4泼尼松1.0-1.3mg/m2pod1-4PDA硼替佐米9mg/m2ivd1,4,8,11阿霉素60mg/m2ivd1-4地塞米松iv第1周期：1.3mg/m2d1-4，0,4,5,9mg/m28-11,15-18

期：d1-4VTD硼替佐米ivd1,4,8,11沙利度胺pod