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窝沟封闭(Pit-and-fissure
sealants)Q.H.
Zhi支清惠窝沟封闭于1967年由CuetoandBuonocore首次报道,今天在牙科被广泛应用和推荐。儿童的点隙窝沟龋流行病学流行率:咬合面龋损占总的龋损的50.9%6~7
years
old12~14
years
old44%65%氟化物防龋对窝沟龋效果不理想窝沟是龋损易发部位咬合面的解剖结构
容易滞留细菌有机塞、食物残渣、菌斑阻塞窝沟点隙,阻止了氟化物的渗透较薄的牙釉质层
对龋病易感窝沟的解剖形态浅而宽,容易清洁深而窄,容易滞留食物残渣和细菌,窝沟的分类V型I
型不易清洁窝沟龋的发展龋损首先发生在侧壁进展至窝沟底部三角形病损进展期预防窝沟龋的历史回顾预防性充填法(Prophylacticodontotomy)制备I类洞,银汞充填窝沟磨除术(Prophylacticodontoplasty)以圆钻磨除深窝沟窝沟封闭(Pit
and
fissure
sealant)窝沟封闭的发展历史第一代:365nm
紫外光固化,操作时间长,效果不理想第二代:Bis-GMA,
化学固化第三代:430~490nm
可见光,方便,效果好3M
Consisesealant第四代:释氟性窝沟封闭剂Pulpdentsealant窝沟封闭适应证萌出少于4年磨牙深的、易滞留、窄的窝沟点隙窝沟有软化和混浊倾向其他牙齿有咬合面或光滑面龋;被封闭牙没有邻面龋患者接受适当的全身性或局部用氟,但仍然龋活跃窝沟封闭非适应证牙齿萌出四年以上,窝沟经常有色素沉着牙齿未完全萌出,有牙龈覆盖除非患者为龋活跃个体,否则前磨牙不作窝沟封闭牙面窝沟浅而宽,自洁作用好患牙有邻面龋,已有咬合面龋洞(需用充填治疗)患者饮用水源不含氟,患者不能配合龋病预防计划封闭剂成分树脂基质Resin
baseBis-GMA稀释剂Thinner
(dicrease
the
viscosity) methyl
methacrylate
(MMA)et
al.引发剂Initiator self-curelight-cure
(430~490nm
visible
light)填料Filling
(increase
the
compressivestrenth,
rigidity
and
abrasive
resistance)颜色Color (easy
to
identify)酸蚀技术1955由Buonocore首先介绍35~38%磷酸恒牙30秒乳牙60
秒有机质含量高 更耐酸酸蚀使光滑的牙釉质表面变得不规则,增加其表面自由能。当液体树脂基质置于不规则的酸蚀表面,树脂通过毛细管作用浸入表面,单体聚合,树脂扣入牙釉质表面。树脂微突的形成是封闭剂-牙釉质粘结的基本机制。酸蚀技术牙釉质酸蚀形成三种微结构形式:釉小柱核心溶解,周围不溶解釉小柱周围溶解,核心完好不典型形态操作步骤牙面清洁Teeth
cleaning酸蚀Acid-etch冲洗吹干Washing
and
evaporation放置封闭剂Sealant
application封闭剂固化Solidify
of
sealants检查Examination操作步骤1.
牙面清洁Teeth
cleaningcleaning
teeth
thoroughlyslow
speed
hand
piece,
mini
dental
brush
orrubbercap,pumice
powderor
dentifrices
withoutfluoride注意:不能使用脂类清洁剂或含填料的磨料必要时去除可疑龋操作步骤2.
酸蚀Acid-etch35%磷酸,2/3
牙尖斜面,恒牙30s,
乳牙60s,注意:轻轻搅拌以保证牙面接触新鲜的酸,不能污染酸蚀面,酸蚀后的白垩色操作步骤3.
冲洗和干燥Washing
and
evaporation彻底冲洗以去除酸及反应产物,以压缩空气或无色酒精干燥注意:不污染酸蚀面,白垩色操作步骤4.
放置封闭剂自凝性Self-cure
sealants:
mixing
for
10s
to
15s,apply
in
45s.光固化Light-cure
sealants:
apply
on
acid-etched
surfaces,fully
penetration
of
sealant
intothe
fissures,enough
thickness
to
provide
enoughcompressive
strenth,
rigidity操作步骤5.
封闭剂的固化Solidify
of
sealants自凝性self-cure
sealants:
1~2
minutes光固化light-cure
sealants:
430~490nm
visiblelight,1mm
distance,
20~40s操作步骤6.
检测及调牙合(必要时)固化情况、粘结、气泡、遗漏点隙、过度封闭、调牙合检查after
3
months,
6
months
or
1
year
interval,脱落重新封闭临床效果临床评价保留率retention
rate=封闭剂保留的牙数/所有检查的牙齿X100%龋降低相对有效率relative
effectiveness
of
decreased
dental
caries=(对照组患龋率-实验组患龋率)/对照组患龋率X100%临床效果Sealants,
by
providing
a
physical
barrier,
inhibitmicroorganisms
and
food
particles
from
collecting
in
pitsand
fissures.
Sealants
are
highly
effective
in
preventingdental
caries
in
pits
and
fissures
of
teeth
when
applied
bytrained
operators.
Sealant
should
be
placed
on
pits
andfissures
of
children’s
and
adolescents’
permanent
teethwhen
it
is
determined
that
the
tooth
or
the
patient
is
at
riskof
developing
caries.
Fissure
sealing
can
be
recommendedas
a
caries
preventive
measure.Judit
S.
Fissuresealing.
Areview,Fogorv
Sz.
2008Aug;101(4):137-46.与临床效果有关的其他因素下颌保留率比上颌高前磨牙保留率比磨牙高大多数脱落发生在前6个月,重新封闭增加了龋病预防效果成功率因牙齿的选择、术者的技巧、工作态度而异系统性评价Systematic
evaluationof
clinical
effectivenessClinical
effectiveness
of
resin
sealants
to
permanent
teethThe
relative
risks
(RR)
to
develop
dental
caries
after
resinsealants
is
0.14,
0.24,
0.30,
and
0.43
at
12,
24,
36,
and48~54
months,
respectively.
Resin
sealants
were
effectivein
caries
prevention.Abovuo-Saloranta,
et
al.
Cochrane
Database
Syst
Rev.1993Systematic
evaluation
of
clinicaleffectivenessClinical
effectiveness
of
resin
sealants
to
permanent
teethThe
relative
caries
risk
reduction
pooled
estimate
of
resin-basedsealants
on
permanent
1st
molars
was
33%
(relative
risk
=
0.67;CI
=
0.55-0.83).
The
effect
depended
on
retention
of
thesealant.
In
conclusion,
the
review
suggests
limited
evidence
thatfissure
sealing
of
1st
permanent
molars
with
resin-basedmaterials
has
a
caries-preventive
effect.
The
evidence
isincomplete
for
permanent
2nd
molars,
premolars
and
primarymolars
and
for
glass
ionomer
cements.Mejare
I,
et
al.
Caries-preventive
effect
of
fissure
sealants:
asystematic
review.
Acta
Odontol
Scand.
2003
Dec;61(6):321-30.Systematic
evaluation
of
clinicaleffectivenessClinical
effectiveness
of
resin
sealants
to
permanent
teethResin
sealants
are
effective
in
preventing
dental
caries
onocclusal
surfaces
of
permanent
teeth.The
evidence
is
incomplete
for
primary
teeth.Systematic
evaluation
of
clinicaleffectivenessClinical
effectiveness
of
glass
ionomer
(GIC)
sealantsOnly
one
parallel
study
used
GIC
sealants.
No
statistic
difference
wasfound
after
24
months.
The
retention
rates
of
different
GIC
weredifferent
and
the
evidence
was
incomplete.
Better
designed
studieswere
needed
to
prove
the
preventive
effect
of
GIC
sealants.Abovuo-Saloranta,
et
al.
Cochrane
Database
Syst
Rev.
1993Systematic
evaluation
of
clinicaleffectivenessComparision
between
self-cure
and
light-cure
sealantsno
significant
difference
between
them
regarding
theretention
rate
and
the
preventive
effectComparision
between
sealants
with
and
without
fluorideno
significant
difference
between
them
regarding
theretention
rate
and
the
preventive
effectComparision
between
GIC
and
resin
sealantsincomplete
evidence
to
show
there’s
a
differenceSystematic
evaluation
of
clinicaleffectivenessThe
accepted
reviews
provided
no
evidence
of
superiority
ofeither
sealant
material.
Six
trials
were
included
for
meta-analysis.
The
pooled
odds
ratio
was
0.96,
95%
CI
0.62-1.49,indicating
no
difference
in
the
caries-preventive
effect
of
GIC
and
resin-based
fissure
sealant
material.
This
systematic
reviewwith
meta-analysis
found
no
evidence
that
either
material
wassuperior
to
the
other
in
the
prevention
of
dental
caries.
Thus,bothmaterialsappearequallysuitablefor
clinicalapplicationasa
fissure
sealant
material.Yengopal
V,
Mickenautsch
S,
Bezerra
AC,
Leal
SC.Caries-preventive
effect
of
glass
ionomer
and
resin-basedfissuresealants
on
permanent
teeth:
a
meta
analysis.
J
Oral
Sci.
2009Sep;51(3):373-82.Systematic
evaluation
of
clinicaleffectivenessPit
and
fissure
sealants
for
preventing
dental
decay
in
thepermanentteeth
of
childrenandadolescents.Ahovuo-Salorant
A,
Cochrane
Database
Syst
Rev.
2008
Oct8;(4):CD001830.OBJECTIVES:The
primary
objective
of
this
review
was
to
evaluate
thecaries
prevention
of
pit
and
fissure
sealants
in
children
andadolescents.Systematic
evaluation
of
clinicaleffectivenessMAINRESULTS:Sixteen
studies
were
included
in
the
review;
7
studies
provided
datafor
comparison
of
sealant
versus
control
without
sealant
and
10studies
for
comparison
of
sealant
versussealant.Systematic
evaluation
of
clinicaleffectivenessMAINRESULTS:Five
split-mouth
studies
and
one
parallelgroup
study
with
5
to
10
yearold
children
found
a
significant
difference
in
favour
of
second
or
thirdgeneration
resin-based
sealants
on
first
permanent
molars,
comparedto
a
control
without
sealant,
witha
pooled
RRof
0.13
(95%
confidenceinterval
(CI)
0.09
to
0.20),
0.22
(95%
CI
0.15
to
0.34),
0.30
(95%CI0.22
to
0.40),
and
0.40
(95%
CI
0.31
to
0.51)
at
12,
24,
36
and
48-54months
followup,
respectively.
Further,
one
of
those
studies
with9years
of
follow
up
found
significantly
more
caries
in
the
control
groupcompared
to
resin
sealant
group;
27%
of
sealed
surfaces
weredecayed
compared
to
77%
of
surfaces
without
sealant.The
results
ofthe
studies
comparing
different
sealant
materials
wereconflicting.Systematic
evaluation
of
clinicaleffectivenessAUTHORS'
CONCLUSIONS:Sealing
is
a
recommended
procedure
to
prevent
caries
ofthe
occlusal
surfaces
of
permanent
molars.
Theeffectiveness
of
sealants
is
obvious
at
high
caries
risk
butinformation
on
the
benefits
of
sealing
specific
to
differentcaries
risks
is
lacking.影响窝沟封闭预防效果的因素窝沟封闭对预防龋病是有效的自凝性封闭剂比光固化的更有效封闭剂的预防效果随时间递减封闭剂和加氟联合预防效果更好Liodra
JC,
et
al.
Factors
influencing
the
effectiveness
of
sealants-ameta-analysis,
Community
Dent
Oral
Epidermal
1993,21:261-8窝沟封闭的其他问题酸蚀后牙面的龋易感性即使封闭剂脱落,酸蚀后牙面在酸性溶液中的溶解度与未酸蚀牙面相近酸蚀后牙面唾液污染唾液污染阻止了树脂微突的形成,造成封闭剂脱落、细菌侵入,引起龋齿以压缩空气、橡皮障或棉卷隔湿唾液污染后重新酸蚀窝沟封闭的其他问题早期窝沟龋的封闭酸蚀
杀死窝沟中的微生物封闭剂
阻止细菌的营养供应酸蚀后少于3%细菌存活在窝沟封闭后早期龋停止进展封闭性充填Sealant
restorationThe
sealant
restoration
is
indicated
primarily
on
theocclusal
surfaces
of
permanent
molars
and
premolars
andmay
also
be
indicated
for
primary
molars.
They
are
mostappropriate
when
the
prepared
cavity
in
a
pit
or
fissure
issmall
and
discrete.
Larger
cavities
wou
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