2022年四川省乐山市公共英语五级(笔试)

2022年四川省乐山市公共英语五级(笔试)学校:________班级:________姓名:________考号:________

一、1.ListeningComprehension(15题)1.WanghassomeexperienceaboutCAD.

A.TrueB.Fasle

2.PartB

Directions:Youwillhear3conversationsortalksandyoumustanswerthequestionsbychoosingA,B,CorD.YouwillheartherecordingONLYONCE.

听力原文：W：Doyouenjoyyourwork?Doyouenjoymeetingpeople?

M：Yes．Sometimes．I'vegottobehonest．Sometimes．

W：So，somepeopleyoulikeandsomeyoudon't?

M：Yeah，it’slikealotofthings，meetingthegeneralpublic．Yougetgooddays，andyougetbaddays．ButIdoenjoythejob．Ilikethefreedomofthejob，beingself-employed．

W：Doyouevergetdifficultpassengers?

M：Yes，sometimes．

W：Whatsortofthingsdotheygetupto?

M：Iwouldsaysometimesalotofdifficultpassengersarepeoplewhodon'tgoincabsalotandthey'reunfamiliarwithprocedures．especiallyifyouworknights．Peopledrinkingortheextrasthatwouldbeincludedonthetariffafteracertaintimeofnight．

W：Youmeantheyarguewithyouovermoney?

M：Yes，thatcanhappen．Ortheway…thegoodthingis，peoplecanargueaboutthewaythatyougoonacertainroutebecausetheyalwaysknowbetter．Butninetimesoutoftentheroutethattheytakeyouonisfarlongerso，youknow，they'retheeventuallosers．

W：Soifyoudohaveadifficultpassengeryouwanttogetridof．whatdoyoudo?

M：I'dstopthecabandtellthemtogetout．

W：Doesthatoftenhappen?

M：Mmm，it'shappenedtomethreetimes．Andthey'vegotout．SoI，Imyselfhaven'thadalotofproblemswithdifficultpeople，youknow．

W：Whenyoupickuptouristsaspassengers，whatkindofplacesdotheyliketogoto?

M：IsupposethemostfamouslandmarkisBuckinghamPalace．theTowerofLondon，maybeHarrods；butcertainlyBuckinghamPalace．

Whatdoesthemando?

A.Ataxi-driver．

B.Abusdriver．

C.Apoliceman．

D.Atouristguide．

3.AlldirectorsontheBoardarefull-timeemployeesinthecompany.

A.TrueB.Fasle

4.Thespeakerwillintroducesixdepartmentalmanagersonebyone.

A.TrueB.Fasle

5.Astrokevictimcanputglovesonbothhishands.

A.TrueB.Fasle

6.Backinhisowncountry,Mr.WangstudiedC-languageandchemistry.

A.TrueB.Fasle

7.Youcanfindyournoseinthedarknessbecauseofyour"feltimage".

A.RightB.Wrong

8.Paulcouldreachalltheswitchesbecausetheywereoriginallyinstalledattherightheightofhim.

A.TrueB.Fasle

9.Howmuchtimedothemanandthewomanhavebeforetheyaddresstheclass?

A.Lessthantenminutes.

B.Abouttwentyminutes.

C.Forty-fiveminutes.

D.Overanhour.

10.Studentscanenjoyasimplebookingandenrolmentprocedureinsomechains.

A.TrueB.Fasle

11.Afterdeliveringthenewinformation,whyshouldthespeakeralsogivehisaudiencesometime?

12.PartA

Directions:Youwillhearatalk.Asyoulisten,answerQuestions1-10bycirclingTRUEorFALSE.YouwillhearthetalkONLYONCE.Younowhave1minutetoreadQuestions1-10.

听力原文：W:Comein,please.

M:Goodmorning,Dr.Wilson.

W:Goodmorning,Wang.Hownicetomeetyouagain.Takeaseat...whydon'tyou,please.Whendidyougettotheuniversity?

M:Iarrivedyesterday.

W:Well...areyoulivinginthecollege?

M:No,IamwithanEnglishfamily...actually...becauseIwanttoimprovemyspeaking.

W:Oh,fine.Right,didyoutakealanguageproficiencytestbeforeyoucame?

M:Yes.Uhh...myOverallBandis6,but...unfortunatelymyspeakingscoreisonly5.

W:OK,youknow,hereinthisuniversity,youhavetotakeourownEnglishtestbeforeyouattendanylectures.So,firstofall,whatwe'vegottodois,wehavetomakeanarrangementforthetestdate.Umm...willtomorrowbeallrightforyou?

M:Yeah,Ihavetimetomorrowmorning.

W:Good,then.Tomorrowatten.Idon'tthinkthetestwillbeanyproblemforyou.Now,let'smakesureyoumakegooduseofyourtimehere.Let'sputitlikethis.Whatexactlydoyouwanttoaccomplishinthenext12months?

M:I'minterestedincomputerlanguagetranslation,Imean,fromEnglishtoChineseandChinesetoEnglish.I'lltry,ifpossible,toproducesoftwareoradevicewhichcanserveasaninterpreter.

W:Yes,couldyoubeabitmorespecificabout...er...thedevice?

M:Forinstance,whenyoutalktothedeviceinEnglishitwilltranslateyourwordsintoChineseandviceversa.

W:Uhuh...doyoumeanit'llbeascompetentas...er...ahumaninterpreter?

M:Yes...well,I'llletitdealwithgeneralsituations,atleast.

W:Fascinating...andhowbigwillthedeviceitselfbe,doyouthink?

M:Thesizeofacigarettepack,Ithink.Sopeoplecanputitintheirpocket.

W:Really?Well,thatcouldbeaPh.Dproject.Tellmewhatyouhavedonesofar.

M:Inmyfouryearsofundergraduatestudy,Istudiedelectronics,advancedmathematics,hardwaredesigning,somecomputerlanguagesandprogramwriting.

W:Yes,buthaveyoudoneanypracticaljobs?Imean,haveyouwrittenanyprogramsforpracticaluse?

M:IhadbeeninvolvedinaprojectforCADinashipyard.

W:Computeraideddesign.Thatwasprobablyagoodexperience,but,unfortunately,itmaynothelpyourpresentprojectmuch.AreyoufamiliarwiththeC-language?

M:No.

W:Uhuh...thephoneticprocessingsystem,doyouknowhowsuchasystemworks?

M:Whatdoyoumeanby"phoneticprocessingsystem"?

W:Well,youknow,Englishisspokenbydifferentpeoplewithdifferentaccents.YourEnglishaccentisdifferentfrommine,andofcoursemineisnotthesameasmycolleagues'.SoasIseeit,yourdevicewouldhavetobeabletorecogniseandunderstanddifferentaccents.

M:Oh,Isee.IthinkIcanlearntheC-languageandthephoneticprocessingsystemhere.

W:Well,that'sprobablytrue,butyou'vegotonlytwelvemonthsandyouwantadegree,don'tyou?M:Yes.

W:OK,sothere'retwowaysofstudyingforadegreehere.Youeithertakesixcourses,passtheirexamsandhaveyourdissertationacceptedortheotherwayisyoudosomeresearchworkandsubmityourprojectreport.M:IthinkI'lltakethesecondway,

W:Fine,butareyousureyoucanfinishyourprojectintwelvemonths?

M:Idon'tknow,butIcanworktwelvehoursperdayandsevendaysperweek.

W:Well,I'dsuggestyouspendsometimeinourlibrary,tryingtofindoutwhatotherstudentshavedonebeforeandperhapsreconsideryourownproject,tosomeextent.Youmightnarrowyourresearcharea,concentratingonsolvingoneortwomajorproblems.And,it'dbeagoodideatotalktoyourcolleaguesinthelab,first.Anyway,I'msurewecanworkoutsomethinggood.ShallIseeyouagaininthreedays'time?

M:A11rig

A.TrueB.Fasle

13.Accordingtothespeaker,whatdoesamanagerhavetotreateveryoneofhisstaffas?

14.Whathasgivenwomenanindependenceinformingafamily?

15.Whichpowerdoesthemansuggest?

A.Waterpower.

B.Windpower.

C.Solarpower.

D.Electronicalpower.

二、2.UseofEnglish(10题)16.(34)

17.(41)

18.(50)

19.

【C19】

20.(38)

21.

【C18】

22.(40)

23.

【C4】

24.

【C11】

25.

【C6】

三、3.ReadingComprehension(15题)26.

WhatadvicemightMaquetgivetothosewhohaveacrucialtestthenextday?

A.Memorizinggrammarwithgreatefforts.

B.Studytextbookswithcloseattention.

C.Havetheirbrainimagesrecorded.

D.Enjoytheirsleepatnightsoundly.

27.

Whichofthefollowingistrueaccordingtothetext?

A.TheHartspreferapublicuniversitytoaprivateone.

B.Itismucheasiertopaythetuitionatpresent.

C.Allstudentscangettheaidpackage.

D.Traditionalscholarshipsarestillattractivetosomefamilies.

28.PartB

Directions:Inthefollowingarticlesomeparagraphshavebeenremoved.ForQuestions66-70,choosethemostsuitableparagraphfromthelistA-Ftofitintoeachofthenumberedgaps.Thereisoneparagraphwhichdoesnotfitinanyofthegaps.MarkyouranswersonANSWERSHEET1.

Inthefollowingarticlesomeparagraphshavebeenremoved.ForQuestions66～70,choosethemostsuitableparagraphfromthelistA～Ftofitintoeachofthenumberedgaps.Thereisoneparagraphwhichdoesnotfitinanyofthegaps.

A．Thereremained,however,the“easier”labor—thelaborthatrequiredthehumaneyes,ears,judgmentandmindbutnosweating.Itneverthelesshaditsmiseries,forittendedtobedull,repetitious,andboring.Andthereisalwaysthesoursenseofendlesslydoingsomething.unpleasantundercompulsion.

B．Foronething,muchofhumaneffortthatistodayputinto“mimingtheworld”willbeunnecessary.Withcomputers,robotsandautomation,agreatdealofthedailygrindwillappeartoberunningitself.Thisisnothingstartling.ItisatrendthathasbeenrapidlyonitswayeversinceWorldWarⅡ.

C．Andnowwestandatthebrinkofachangethatwillbethegreatestofall,forworkinitsoldsensewilldisappearaltogether.Tomostpeople,workhasalwaysbeenanefforffulexercisingofmindorbody—compelledbythebitternecessityofearningthenecessitiesoflife—plusanoccasionalperiodofleisureinwhichtorestorhavefun.

D．Clearlytherewillbeapainfulperiodoftransition,onethatisstartingalready,andonethatwillbeinfullswingasthe21stcenturybegins.

E．Inthefirstplace,thecomputeragewillintroduceatotalrevolutioninournotionsofeducation,andisbeginningtodosonow.Thecomingofthecomputerwillmakelearningfun,andasuccessfullystimulatedmindwilllearnquickly.Itwillundoubtedlyturnoutthatthe“average”childismuchmoreintelligentandcreativethanwegenerallysuppose.Therewasatime,afterall,whentheabilitytoreadandwritewasconfinedtoaverysmallgroupof“scholars”andalmostallofthemwouldhavescoutedthenotionthatjustaboutanyonecouldlearntheintricaciesofliteracy.Yetwithmasseducationgeneralliteracycametobeafact.

F．Thismeansthatthedull,theboring,therepetitious,themind-stultifyingworkwillbegintodisappearfromthejobmarket—isalreadybeginningtodisappear.This,ofcourse,willintroducetwovitalsetsofproblem—isalreadyintroducingthem.

Periodicallyinhistory,therecomeperiodsofgreattransitioninwhichworkchangesitsmeaning.Therewasatime,perhaps10,000yearsago,whenhumanbeingsstoppedfeedingthemselvesbyhuntinggameandgatheringplants.andincreasinglyturnedtoagriculture.Inaway,thatrepresentedtheinventionof“work”.

Then,inthelatterdecadesofthe18thcentury,astheIndustrialRevolutionbeganinGreatBritain,therewasanothertransitioninwhichthesymbolsofworkwerenolongerthehoeandtheplow;theywerereplacedbythemillandtheassemblyline.66．______

WiththeIndustrialRevolution,machinery—poweredfirstbysteam,thenbyelectricityandinternalcombustionengines—tookoverthehardphysicaltasksandrelievedthestrainonhumanandanimalmuscles.

67．______

Andyet,suchjobshavebeencharacteristicofthehumanconditioninthefirstthree-quartersofthe20thcentury.They'vemadetoolittledemandonthehumanmindandspirittokeepthemfreshandalive,madetoomuchdemandforanymachinetoservethepurposeuntilnow.

Theelectroniccomputer,inventedinthe1940'sandimprovedatbreakneckspeed,wasamachinethat,forthefirsttime,seemedcapableofdoingworkthathaduntilthenbeenthepreserveofthehumanmind．Withthecoming

29.PartC

Directions:Answerquestions71-80byreferringtothefollowinggames.

Note:AnswereachquestionbychoosingA,BorCandmarkitonANSWERSHEET1.Somechoicesmayberequiredmorethanonce.

Answerquestions71～80byreferringtothefollowinggames.

Note:AnswereachquestionbychoosingA,B,CorDandmarkitonANSWERSHEET1.Somechoicesmayberequiredmorethanonce.

A=BOOK1B=BOOK2C=BOOK3D=BOOK4

Whichbook(s)say(s)that...

theclimateaffectsthefuturesustainableagriculturaldevelopment?71.______

environmentalcontrolisrelatedwiththenationalrevenues?72.______

theenvironmentalproblemsarenotcausedovernight?73.______

avarietyofspeciesareonthedecrease?74.______

agricultureisalsoafactorforfiledegradationofenvironment?75.______

pollutioncanbecontrolledbyincreasingtheproductioncostofpollutinggoods?76.______

pollutioncontrolneedsthesupportoftechnologyandtechniques?77.______

provideslessonsforagriculture,trade,landu~eandtaxpolicyfromaneconomicperspective?78.______

thedegradationofenvironmentcausesthechangeofclimate?79.______

theapproachestoresearchshouldbeadjustedtothechangingsituation?80.______

ABOOK1

Thebookoffersacomprehensiveperspectiveontheconsequencesandpossiblepolicysolutionsforclimaticchangeaswemoveintothetwenty-firstcentury.Itassessestheimpactofpotentialfeatureglobalclimatechangeonagricultureandtheneedtosustainagriculturalgrowthfortheeconomicdevelopment.

Thebookbeginsbyexaminingtheroleofinternationalresearchinstitutionsinovercomingenvironmentalconstraintsonsustainableagriculturalgrowthandeconomicdevelopment.Theauthorsthendiscusshowagriculturalresearchsystemsmayberestructuredtorespondtoglobalenvironmentalproblemssuchasclimatechangeandlossofgeneticdiversity.Thediscussionthenextendstoconsiderenvironmentalaccountingandindexing,toillustratehowenvironmentalqualitycanbeincludedformallyinmeasuresofnationalincome,socialwelfareandsustainability.Thethirdpartofthebookfocusesontheeffectsofandpolicyresponsestoclimatechange.Chaptersinthispartexaminetheeffectofclimatechangeonproduction,trade,landusepatternsandlivelihoods.Theyconsiderimpactsonthedistributionofincomebetweendevelopedanddevelopingcountriesremainamajoreconomicactivity.Authorstakeonaneconomy-wideperspectivetodrawlessonsforagriculture,trade,landuseandtaxpolicy.

BBOOK2

Theozonelayeristhreatenedbychemicalemissions;theclimateisendangeredfromfossilanddeforestation,andglobalbiodiversityisbeinglostbyreasonofthousandsofyearsofhabitatconversions.Globalenvironmentalproblemsariseoutoftheaccumulatedimpactsfrommanyyears'andmanycountries'economicdevelopment.Inordertoaddresstheseproblemsthestatesoftheworldmustcooperatetomanagetheirdevelopmentprocessestogether--thisiswhataninternationalenvironmentalagreementmustdo.Butcantheworld'scountriescooperatesuccessfullytomanageglobaldevelopment?Howshouldtheymanageit?Whoshouldpayfortheprocess,aswellasfortheunderlyingproblems?

Thisbookpresentsanexaminationofboththeproblemandtheprocessunderlyinginternationalenvironmentallawmaking:therecognitionofinternationalinterdependence,thenegotiationofinternationalagreementsandtheevolutionofinternationalresourcemanagement.Itexaminesthegeneralproblemofglobalresourcemanagementbymeansofgeneralprinciplesandcasestudiesandby

30.

TheGTE'sexampleshowsthat______.

A.efficienttechnologyiscost-effective

B.manymeetingsinacompanyareunnecessary

C.manypositionslikethatofatypistcanbedoneawaywith

D.itdoesn'tcostmuchtoautomatethefacilitiesofacompany

31.PartC

Directions:Answerquestions71-80byreferringtothefollowinggames.

Note:AnswereachquestionbychoosingA,BorCandmarkitonANSWERSHEET1.Somechoicesmayberequiredmorethanonce.

A=RotherhitheB=BarnesC=WillesdenD=King'sCrossWhichcity…

usedtohavelotofproblemssuchasdrugs,streetcrime,etc.?71.______

hastheunpopularstyle.ofarchitecture?72.______

hasthemostexpensiveproperties?73.______

offersbigout-fashionedhousesatlowerprice?74.______

islocatedinaquietresidentialarea?75.______

sawabigincreaseinpricelastyear?76.______

willbuildalotofnewfacilities?77.______

isestimatedtobeagoodinvestment?78.______

encouragesnight-lifecultureforyoungpeople?79.______

createsenergeticmulti-culturalatmosphere?80.______

A

Rotherhithe

Rotherhithemaybemostfamousforitscongestedtunnelbutmanyyoungbuyersarewarmingtoitsriversidecharms.

Itisstillmuchcheaperthanitswatersideneighbors.Thehousingstockispredominately1980sflats,manyarrangedincul-de-sacs(死胡同)andclosesaroundSurreyQuaysRoad.

TheunpopulararchitecturehasledtotheareabeingcalledtheMiltonKeynesofLondonbutpropertiesarespaciousandunfashionablestyle.haskeptpricesdown.

PaulMitchell,ofestateagentsAlexNeil,says,"Thereispreciouslittleperiodproperty,butyouwillgetfarmoreforyourmoneyherethanaVictorianhousewithlotsoforiginalfeaturesdowntheroadinBermondsey."

SurryQuaysshoppingcenterprovidesalltheamenitiesofahighstreetbuttheareaislackinginfun.However,SouthwarkCouncilisintalkstodevelopthe"nighttimeeconomy"whichcouldwellleadtoanincreaseinbarsandrestaurantstocaterfortiegrowingnumberofyoungprofessionalresidents.

"Itispossibletogetagoodthree-bedroomhouseinRotherhithefor280,000,"saysSumineJordaan-Robinson,ofagentsBurwoodMarsih,"Abouteightminutes;walkfromtheJubileelinewhichwillhaveyouinBondstreetin15minutes.TherearerotthatmanyareasinLondonwherethatispossible."

B

Barnes

BarnessitsjustacrosstheriverfromHammersmithinsouthwestLondon,butitcouldnotbemoredifferentfromthenoiseandbustleoftheoppositebank.

IthasbeencalledoneofthelasttrueLondon"villages"withhappyresidentskeepingitsoldschoolcharmsquietfromnoseyoutsidersandpotentialdevelopers.

BeingbytheriverandpredominatelyresidentialgivesBarnesanattractivelylazyvibe.Ithasatraditionalvillagegreencompletewithidyllicduckpondandquaintpub.ThehighstreetisaboutasfarfromthePoundShopandPrimarkambienceofitsneighborsasispossible.

ButbuyingintoBarnesisnotcheap."Familyhousesaresnappedupincrediblyquickly,"claimsChrisCarney,salesnegotiatoratBoileausestateagents."Itisveryhardtogetpropertiesofthissize,withoutsidespacesoclosetoLondon,whichiswhytheyareexpensive."

LargedetachedVicuorianhousesonthetwomainroads,CastlenauandLonsdale,normallyhavebetweenfiveandsevenbedrooms,gardensof120ftandoffstreetparking.Thesesellforanythingbetween￡2millionand￡5million.Bythevillagegreentherearerowsofimmaculateterraced

32.

Thevalueofcompetitionworksagainstthespiritofnationalcooperationinthat______.

A.itmakespeoplenotbelieveinthegovernment

B.itcausespeopletosuspectbutnottotrusteachother

C.itmakespeopleevenunabletocooperatewellonlocallevels

D.itencouragespeopletogainsuccessthroughindividualhardwork

33."TheissueofonlineprivacyintheInteractagefoundnewurgencyfollowingtheSept.11terroristattacks,sparkingdebateoverstrikingthecorrectbalancebetweenprotectingcivillibertiesandattemptingtopreventanothertragicterroristact.Whilepreventingterrorismcertainlyisofparamountimportance,privacyrightsshouldnotbedeemedirrelevant.

Inresponsetotheattacks,Congressquicklypassedlegislationthatincludedprovisionsexpandingfightsofinvestigatorstointerceptwire,oralandelectroniccommunicationsofallegedhackersandterrorists.CivillibertiesgroupsexpressedconcernsovertheprovisionsandurgedcautioninensuringthateffortstoprotectournationdonotresultinbroadgovernmentauthoritytoerodeprivacyrightsofU.S.citizens.Nevertheless,causingfurtherconcerntocivillibertiesgroups,theDepartmentofJusticeproposedexceptionstotheattorney-clientprivilege.OnOct.30,AttorneyGeneralJohnAshcroftapprovedaninterimagencyrulethatwouldpermitfederalprisonauthoritiestomonitorwireandelectroniccommunicationsbetweenlawyersandtheirclientsinfederalcustody,includingthosewhohavebeendetainedbutnotchargedwithanycrime,wheneversurveillanceisdeemednecessarytopreventviolenceorterrorism.

Inlightofthisbroadeningefforttoreachintocommunicationsthatwerepreviouslybelievedtobe"off-limits",theissueofonlineprivacyisnowanevenmorepressingconcern.Congresshastakensomelegislativestepstowardensuringonlineprivacy,includingtheChildren'sOnlinePrivacyProtectionAct,andprovidedprivacyprotectionsforcertainsectorsthroughlegislationsuchastheFinancialServicesModernizationAct.Thelegislationpassedtodatedoesnot,however,provideastatutoryschemeforprotectinggeneralonlineconsumerprivacy.Lackingdefinitivefederallaw,somestatespassedtheirownmeasures.Butmuchofthislegislationisincompleteornotenforced.Moreover,itbecomesunworkablewhenstatescreatedifferentprivacystandards;theInternetdoesnotknowgeographicboundaries,andcompaniesandindividualscannotbeexpectedtocomplywithdiffering,andattimesconflicting,privacyroles.

Ananalysisearlierthisyearof751U.S.andinternationalWebsitesconductedbyConsumersInternationalfoundthatmostsitescollectpersonalinformationbutfalltotellconsumershowthatdatawillbeused,howsecurityismaintainedandwhatrightsconsumershaveovertheirowninformation.

Ataminimum,CongressshouldpasslegislationrequiringWebsitestodisplayprivacypoliciesprominently,inform.consumersofthemethodsemployedtocollectclientdata,allowcustomerstooptoutofsuchdatacollection,andprovidecustomeraccesstotheirowndatathathasalreadybeencollected.AlthoughvariousInternetprivacybillswereintroducedinthe107thCongress,thefocusshiftedtoexpandinggovernmentsurveillanceinthewakeoftheterroristattacks.Plainly,governmenteffortstopreventterrorismareappropriate.Exactlyhowtheseexigentcircumstanceschangethenatureoftheonlineprivacydebateisstilltobeseen.

Concerningtheprotectionofprivacyandincreasedsurveillanceofcommunication,theauthorseemstoinsiston______.

A.thepriorityoftheformeraction

B.theexecutionofthelatterattheexpenseoftheformer

C.tighteningbothpoliciesatthesametime

D.abalancebetweenthetwoactions

34.

FromDr.Dustan'sstudywecaninferthat_____.

A.alow-saltdietmaybeprescribedforsomepeople

B.theamountofsaltintakehasnothingtodowithone'sbloodpressure

C.thereductionofsaltintakecancureahypertensivepatient

D.anextremelylow-saltdietmakesnodifferencetoanyone

35.At18,AshanthiDeSilvaofsuburbanClevelandisalivingsymbolofoneofthegreatintellectualachievementsofthe20thcentury.Bornwithanextremelyrareandusuallyfataldisorderthatleftherwithoutafunctioningimmunesystem(the"bubble-boydisease",namedafteranearliervictimwhowaskeptaliveforyearsinasterileplastictent),shewastreatedbeginningin1990witharevolutionarynewtherapythatsoughttocorrectthedefectatitsverysource,inthegenesofherwhitebloodcells.Itworked.Althoughherlastgene-therapytreatmentwasin1992,sheiscompletelyhealthywithnormalimmunefunction,accordingtooneofthedoctorswhotreatedher,W.FrenchAndersonoftheUniversityofSouthernCalifornia.Researchershavelongdreamedoftreatingdiseasesfromhemophiliatocancerbyreplacingmutantgeneswithnormalones.Andthedreamingmaycontinuefordecadesmore."Therewillbeagene-basedtreatmentforessentiallyeverydisease,"Andersonsays,"within50years."

It'snotentirelyclearwhymedicinehasbeensoslowtobuildonAnderson'searlysuccess.TheNationalInstitutesofHealthbudgetofficeestimatesitwillspend$432millionongene-therapyresearchin2005,andthereisnoshortageofpromisingleads.Thetherapeuticgenesareusuallydeliveredthroughvirusesthatdon'tcausehumandisease."ThevirusissortoflikeaTrojanhorse,"saysRonaldCrystalofNewYorkPresbyterian/WeillCornellMedicalCollege."Thecargoisthegene."

AttheUniversityofPennsylvania'sAbramsohCancerCenter,immunologistCarlJunerecentlytreatedHIVpatientswithageneintendedtohelptheircellsresisttheinfection.AtCornellUniversity,researchersarepursuinggene-basedtherapiesforParkinson'sdiseaseandararehereditarydisorderthatdestroyschildren'sbraincells.AtStanfordUniversityandtheChildren'sHospitalofPhiladelphia,researchersaretryingtofigureouthowtohelppatientswithhemophiliawhotodaymustinjectthemselveswithexpensiveclottingdrugsforlife.Animalexperimentshaveshowngreatpromise.

Butsomehow,thingsgetlostinthetranslationfromlaboratorytopatient.Inhumantrialsofthehemophiliatreatment,patientsshowaresponseatfirst,butitfadesovertime.Andthefieldhasstillnotrecoveredfromthesetbackitsufferedin1999,whenJesseGelsinger,an18-year-oldwithararemetabolicdisorder,diedafterreceivinganexperimentalgenetherapyattheUniversityofPennsylvania.Someexpertsworrythatthefieldwillbetarnishedfurtherifthenextpeopletobenefitarenotpatientsbutathletesseekinganedge.Thissummer,researchersattheSalkInstituteinSanDiegosaidtheyhadcreateda"marathonmouse"byimplantingagenethatenhancesrunningability;already,officialsattheWorldAnti-DopingAgencyarepreparingtotestathletesforsignsof"genedoping".Buttheprincipleisthesame,whetheryou'retryingtohelpahealthyrunnerrunfasterorallowamuscular-dystrophypatienttowalk."Everybodyrecognizesthatgenetherapyisaverygoodidea,"saysCrystal."Andeventuallyit'sgoingtowork."

ThecaseofAshanthiDesilvaismentionedinthetextto______.

A.showthepromiseofgene-therapy

B.giveanexampleofmoderntreatmentforfataldiseases

C.introducetheachievementofAndersonandhisteam

D.explainhowgene-basedtreatmentworks

36.PartA

Directions:ReadthefollowingtextsandanswerthequestionswhichaccompanythembychoosingA,B,CorD.MarkyouranswersonANSWERSHEET1.

Whenitcomestotheslowingeconomy,EllenSperoisn'tbitinghernailsjustyet.Butthe47-year-oldmanicuristisn'tcutting,fillingorpolishingasmanynailsasshe'dliketo,either.Mostofherclientsspend$12to$50weekly,butlastmonthtwolongtimecustomerssuddenlystoppedshowingup.Speroblamesthesofteningeconomy."I'magoodeconomicindicator,"shesays,"Iprovideaservicethatpeoplecandowithoutwhenthey'reconcernedaboutsavingsomedollars."SoSperoisdownscaling,shoppingatmiddle-browDillard'sdepartment