Bersacapavir-JNJ-6379-DataSheet-生命科学试剂-MedChemExpress

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEBersacapavirCat.No.:HY-109168CASNo.:1638266-40-6Synonyms:JNJ-6379;JNJ-56136379分⼦式:C₁₆H₁₄F₄N₄O₃S分⼦量:418.37作⽤靶点:HBV作⽤通路:Anti-infection储存⽅式:Powder-20°C3years4°C2yearsInsolvent-80°C6months-20°C1month溶解性数据体外实验DMSO:100mg/mL(239.02mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制备储备液1mM2.3902mL11.9511mL23.9023mL5mM0.4780mL2.3902mL4.7805mL10mM0.2390mL1.1951mL2.3902mL请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。储备液的保存⽅式和期限：-80°C,6months;-20°C,1month。-80°C储存时，请在6个⽉内使⽤，-20°C储存时，请在1个⽉内使⽤。体内实验请根据您的实验动物和给药⽅式选择适当的溶解⽅案。以下溶解⽅案都请先按照InVitro⽅式配制澄的储备液，再依次添加助溶剂：(为保证实验结果的可靠性，澄的储备液可以根据储存条件，适当保存；体内实验的⼯作液，建议您现⽤现配，当天使⽤；以下溶剂前显⽰的百分⽐指该溶剂在您配制终溶液中的体积占⽐；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的⽅式助溶)1.请依序添加每种溶剂：10%DMSO>>90%cornoil1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemESolubility:≥2.5mg/mL(5.98mM);ClearsolutionBIOLOGICALACTIVITY⽣物活性Bersacapavir⼀种新型的⼄型肝炎病毒⾐组装调节剂>。户使⽤本产品发表的科研⽂献•AnalMethods.2021Dec17.Seemorecustomervalidationsonwww.MedChemEREFERENCES[1].VandenbosscheJ,JessnerW,vandenBoerM,BiewengaJ,BerkeJM,TalloenW,DeZwartL,SnoeysJ,YogaratnamJ.Pharmacokinetics,SafetyandTolerabilityofJNJ-56136379,aNovelHepatitisBVirusCapsidAssemblyModulator,inHealthySubjects.AdvTher.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax: