Pinaverium-bromide - Calcium Channel 抑制剂 - 生命科学试剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEPinaverium bromideCat. No.: HY-111613CAS No.: 53251-94-8分式: CHBrNO分量: 591.42作靶点: Calcium Channel作通路: Membrane Transporter/Ion Channel; Neuronal Signaling储存式: Powder -20C 3 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO

2、: 62.5 mg/mL (105.68 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 1.6908 mL 8.4542 mL 16.9085 mL5 mM 0.3382 mL 1.6908 mL 3.3817 mL10 mM 0.1691 mL 0.8454 mL 1.6908 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验

3、的作液，建议您现现配，当天使；澄的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (3.52 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (3.52 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSol

4、ubility: 2.08 mg/mL (3.52 mM); Clear solution1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活性 Pinaverium bromide种对胃肠道具有选择性的L型 钙通道 阻滞剂，能有效缓解疼痛、腹泻和肠道不适，对肠易激综合征 (IBS) 患者有良好的治疗效果，且不良反应 1。IC50 & Target Calcium channel 1.REFERENCES1. Dai Y, et al. Effect of pinaverium bromide on stress-induced colonic smooth muscle contractility disorder in rats. World J Gastroenterol.2003 Mar;9(3):557-61.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>