Angelicin-Isopsoralen-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEAngelicinCat. No.: HY-N0763CAS No.: 523-50-2Synonyms: Isopsoralen分式: CHO分量: 186.16作靶点: Others作通路: Others储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 33.33 mg/mL (179.04 mM; Need ultrason

2、ic)H2O : 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (13.43 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (13.43 mM); Clear solution1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活性 异补脂素 (Angelicin)种天然的三环芳烃化合物，结构上跟补脂素有关，具有抗癌、抗炎、抗病毒等活性。具有

3、细胞毒性，IC50：49.56 M；抑制MHV-68，IC50: 5.39 g/ml (28.95 M)。REFERENCES1. Md. Ataur Rahman, Angelicin induces apoptosis through intrinsic caspase-dependent pathway in human SH-SY5Y neuroblastoma cells.Molecular and Cellular Biochemistry October 2012, Volume 369, Issue 1-2, pp 95-1042. Hye-Jeong Cho, et al.

4、Antiviral activity of angelicin against gammaherpesviruses. Antiviral Research Volume 100, Issue 1, October2013, Pages 75833. Fang Liu, et al. Angelicin regulates LPS-induced inflammation via inhibiting MAPK/NF-B pathways. Journal of Surgical ResearchVolume 185, Issue 1, November 2013, Pages 300309McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: