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1、 2021-6-28 2021-6-29 2021-6-29 2021-6-30 2021-6-30 2021-7-4 2021-7-4 2021-7-14 2021-7-14Miller D, et al. Clinically isolated syndromes suggestive of multiple sclerosis,part I: natural history, pathogenesis,diagnosis,and prognosis. Lancet Neurol 2005;4:281-288Miller D, et al. Clinically isolated synd

2、romes suggestive of multiple sclerosis,part I: natural history, pathogenesis,diagnosis,and prognosis. Lancet Neurol 2005;4:281-288Miller D, et al. Clinically isolated syndromes suggestive of multiple sclerosis,part I: natural history, pathogenesis,diagnosis,and prognosis. Lancet Neurol 2005;4:281-28

3、8Miller D, et al. Clinically isolated syndromes suggestive of multiple sclerosis,part I: natural history, pathogenesis,diagnosis,and prognosis. Lancet Neurol 2005;4:281-288Pelidou S-H, Giannopoulos S,et al Therapeutics and Clinical Risk Management, 2021, 4(3): 627-630Thrower BW. Neurology,2007,68(su

4、ppl 4):s12-s15Thrower BW. Neurology,2007,68(suppl 4):s12-s15Miller D, et al. Clinically isolated syndromes suggestive of multiple sclerosis,part I: natural history, pathogenesis,diagnosis,and prognosis. Lancet Neurol 2005;4:281-288Miller D, et al. Clinically isolated syndromes suggestive of multiple

5、 sclerosis,part I: natural history, pathogenesis,diagnosis,and prognosis. Lancet Neurol 2005;4:281-288研讨1 ：CISMS 复发例数(%) 复发时间(m)MOG/MBP抗体(-) 9/39(23%) 45mMOG抗体(+) 35/42(83%) 15mMOG/MBP抗体(+) 21/22(95%) 7mMiller D, et al. Clinically isolated syndromes suggestive of multiple sclerosis,part I: natural h

6、istory, pathogenesis,diagnosis,and prognosis. Lancet Neurol 2005;4:281-288Miller D, et al. Clinically isolated syndromes suggestive of multiple sclerosis,part I: natural history, pathogenesis,diagnosis,and prognosis. Lancet Neurol 2005;4:281-288Miller D, et al. Clinically isolated syndromes suggesti

7、ve of multiple sclerosis,part I: natural history, pathogenesis,diagnosis,and prognosis. Lancet Neurol 2005;4:281-288Miller D, et al. Clinically isolated syndromes suggestive of multiple sclerosis,part I: natural history, pathogenesis,diagnosis,and prognosis. Lancet Neurol 2005;4:281-288Pelidou S-H, Giannopoulos S,et al.clinically isolated syndromes-predicting and delaying multiple sclerosis.Therapeutics and Clinical Risk Management, 2021, 4(3): 627-6301A1B1C1C1D1D1D2B2C2D2DT2MRACBV双侧桥臂无异常信号双侧桥臂无异常信号ourn

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