Garenoxacin-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemEGarenoxacin(Standard)Cat.No.:HY-17460RCASNo.:194804-75-6分子式:C₂₃H₂₀F₂N₂O₄分子量:426.41作用靶点:Bacterial;Topoisomerase;DNA/RNASynthesis;Antibiotic作用通路:Anti-infection;CellCycle/DNADamage储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 Garenoxacin(Standard)是Garenoxacin的分析标准品。本产品用于研究及分析应用。Garenoxacin(BMS284756)是一种具有口服活性的喹诺酮类抗生素(antibiotic)，对各种革兰氏阳性和革兰氏阴性细菌、厌氧菌和复养微生物具有广泛的活性。REFERENCESWaitesKB,etal.Invitrosusceptibilitiestoandbactericidalactivitiesofgarenoxacin(BMS-284756)andotherantimicrobialagentsagainsthumanmycoplasmasandureaplasmas.AntimicrobAgentsChemother.2003Jan;47(1):161-5.InceD,etal.DualtargetingofDNAgyraseandtopoisomeraseIV:targetinteractionsofgarenoxacin(BMS-284756,T-3811ME),anewdesfluoroquinolone.AntimicrobAgentsChemother.2002Nov;46(11):3370-80.ZhaoX,etal.Mutantpreventionconcentrationofgarenoxacin(BMS-284756)forciprofloxacin-susceptibleor-resistantStaphylococcusaureus.AntimicrobAgentsChemother.2003Mar;47(3):1023-7.Azoulay-DupuisE,etal.Activitiesofgarenoxacinagainstquinolone-resistantStreptococcuspneumoniaestrainsinvitroandinamousepneumoniamodel.AntimicrobAgentsChemother.2004Mar;48(3):765-73.FukudaY,etal.TherapeuticeffectsofgarenoxacininmurineexperimentalsecondarypneumoniabyStreptococcuspneumoniaeafterinfluenzavirusinfection.DiagnMicrobiolInfectDis.2014Feb;78(2):168-71.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-5895