L-Glutamic-acid-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEL-Glutamicacid(Standard)Cat.No.:HY-14608RCASNo.:56-86-0分⼦式:C₅H₉NO₄分⼦量:147.13作⽤靶点:EndogenousMetabolite;iGluR;Ferroptosis;Apoptosis作⽤通路:MetabolicEnzyme/Protease;MembraneTransporter/IonChannel;NeuronalSignaling;Apoptosis储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性L-Glutamicacid(Standard)L-Glutamicacid的分析标准品。本产品⽤于研究及分析应⽤。L-Glutamicacidisanexcitatoryaminoacidneurotransmitterthatactsasanagonistforallsubtypesofglutamatereceptors(metabolicrhodophylline,NMDA,andAMPA).L-GlutamicacidhasanagonisteffectonthereleaseofDAfromdopaminergicnerveendings.L-Glutamicacidcanbeusedinthestudyofneurologicaldiseases[1][2][3][4][5].IC50&TargetDA[1].REFERENCES[1].LiberatoreF,etal.PermissiveroleformGlu1metabotropicglutamatereceptorsinexcitotoxicretinaldegeneration.Neuroscience.2017Nov5;363:142-149.[2].GiorguieffMF,etal.PresynapticeffectofL-glutamicacidonthereleaseofdopamineinratstriatalslices.NeurosciLett.1977Oct;6(1):73-7.[3].BogaPekmezekmekA,etal.L-GlutamicacidmonosodiumsaltreducestheharmfuleffectoflithiumonthedevelopmentofXenopuslaevisembryos.EnvironSciPollutResInt.2020Nov;27(33):42124-42132.[4].CroceN,etal.HydrochloricacidalterstheeffectofL-glutamicacidoncellviabilityinhumanneuroblastomacellcultures.JNeurosciMethods.2013Jul15;217(1-2):26-30.[5].SalyhaN,etal.Protectiveroleofl-glutamicacidandl-cysteineinmitigationthechlorpyrifos-inducedoxidativestressinrats.EnvironToxicolPharmacol.2018Dec;64:155-163.McePdfHeight1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemECaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-379