Isoxsuprine-hydrochloride-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEIsoxsuprinehydrochloride(Standard)Cat.No.:HY-B1270RCASNo.:579-56-6分⼦式:C₁₈H₂₄ClNO₃分⼦量:337.84作⽤靶点:AdrenergicReceptor;iGluR作⽤通路:GPCR/GProtein;NeuronalSignaling;MembraneTransporter/IonChannel储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性Isoxsuprinehydrochloride(Standard)Isoxsuprinehydrochloride的分析标准品。本产品⽤于研究及分析应⽤。Isoxsuprinehydrochlorideβ肾上腺素受体激动剂，对于⼦宫肌层和胎盘的β肾上腺素受体的Ki值分别为13.65μM和3.48μM。Isoxsuprinehydrochloride也⼀种NMDA受体拮抗剂。IC50&TargetKi:13.65μΜ(myometrialbeta-adrenergicreceptor),3.48μΜ(placcntalbeta-adrenergicreceptor)[1]NMDAreceptor[3]REFERENCES[1].FalkayG,etal.Affinityoftocolyticagentsonhumanplacentalandmyometrialbeta-adrenergicreceptors.JPerinatMed.1986;14(2):109-13.[2].KretschyN,etal.Invitroinhibitionofbreastcancerspheroid-inducedlymphendothelialdefectsresemblingintravasationintothelymphaticvasculaturebyacetohexamide,isoxsuprine,nifedipinandproadifen.BrJCancer.2013Feb19;108(3):570-8.[3].HillJW,etal.Identificationofisoxsuprinehydrochlorideasaneuroprotectantinischemicstrokethroughcell-basedhigh-throughputscreening.PLoSOne.2014May7;9(5):e96761.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:02