医学生物化学与分子生物学（17版）学习通超星课后章节答案期末考试题库2023年

医学生物化学与分子生物学（17版）学习通超星课后章节答案期末考试题库2023年AresearchwasstudyingoxidativephosphorylationinasuspentionofcarefullywashedandisolatedmitochondriaATP,ADP,inorganicphosphate,lactate,lactatedehydrogenase,andoxygenwereintroducedtothesuspension,andhewasabletodemonstrateATPproductionwithinthemitochondria.Theresearchwethenaddedoligomycintothemixture,whichstoppedoxygenuptake.Thisoccurredduetowhichofthefollowing?

参考答案:

Inhibition

of

the

proton

translocating

ATPase

Atwoyear-oldboywasbroughtintotheemergencyroom,sufferingfromseverefastinghypoglycemia.Onphysicalexamination,hewasfoundtohavehepatomegaly.Laboratorytestsindicatedthathealsohadhyperlacticacidemiaandhyperuricemia.Aliverbiopsyindicatedthathepatocytescontainedgreaterthannormalamountsofglycogenthatwasofnormalstructure.Thechildwassubsequentlyfoundtobemissingwhichofthefollowingenzymes?

参考答案:

Glucose6-phosphatase

Aninfantwithanenlargedliverhasaglucose6-phosphatasedeficiency.Thisinfant

参考答案:

cannotmaintainbloodglucoselevelseitherbyglycogenolysisorbygluconeogenesis

Casefilestudy（YoucananswerthequestioneitherinChineseorEnglish)A50-year-oldHispanicfemalepresentstoyourclinicwithcomplaintsofexcessivethirst,fluidintake,andurination.Shedeniesanyurinarytractinfectionsymptoms.Shereportsnomedicalproblems,buthasnotseenadoctorinmanyyears.Onexaminationsheisanobesefemaleinnoacutedistress.Herphysicalexamisotherwisenormal.Theurinalysisrevealedlargeglucose,andaserumrandombloodsugarlevelwas320mg/dL.1.Whatisthemostlikelydiagnosis?2.Whatotherorgansystemscanbeinvolvedwiththedisease?3.Whatisthebiochemicalbasisofthisdisease?

参考答案:

504GatewayTime-out504GatewayTime-outnginx

Case

file

study（You

can

answer

the

question

either

in

Chinese

or

English)A68-year-oldfemaleinahypertensivecrisisisbeingtreatedintheintensivecareunit(ICU)withintravenousnitroprussidefor48hours.Thepatient’sbloodpressurewasbroughtbackdowntonormallevels;however,shewascomplainingofaburningsensationinherthroatandmouthfollowedbynauseaandvomiting,diaphoresis,agitation,anddyspnea.Thenursenoticedasweetalmondsmellinherbreath.Anarterialbloodgasrevealedasignificantmetabolicacidosis.Aserumtestsuggestsametaboliteofnitroprusside,thiocyanate,isattoxiclevels.1.Whatisthelikelycauseofhersymptoms?2.Whatisthebiochemicalmechanismofthisproblem?3.Whatisthetreatmentforthiscondition?

参考答案:

504GatewayTime-out504GatewayTime-outnginx

Epinephrineandglucagonhavewhichoneofthefollowingeffectsonglycogenmetabolismintheliver?

参考答案:

Glycogenphosphorylaseisactivated,whereasglycogensynthaseisinactivated.

HowmanynetmoleculesofATParegeneratedintheconversionofglucosetopyruvate?

参考答案:

2

Inwhichcompartmentofthecelldoesglycolysisoccur?

参考答案:

Solublecytoplasm(cytosol)

Mostofthereducingequivalentsutilizedforsynthesisoffattyacidscanbegeneratedfrom

参考答案:

Thepentosephosphatepathway

NADHisrequiredfortheone-stepreactionbywhichpyruvateisconvertedto

参考答案:

lactate

Thecompoundwhichcannotbeconvertedintoglucoseisinanimals.

参考答案:

fattyacid

Thedegradationofglycogennormallyproduces

参考答案:

moreglucose1-phosphatethanglucose

Theelectrontransportchainismadeupoffoursegments(ComplexesI-IVwithO2asthefinalelectronacceptor).Whichstatementbestdescribestheelectrontransportchain?

参考答案:

Electronsflowspontaneouslyfromonecarriertothenext.

ThepentosephosphatepathwaygenerateseachofthefollowingproductsEXCEPT

参考答案:

glucosefromribose5-phosphateandCO2

TheprinciplfunctionoftheTCAcycleisto

参考答案:

transferelectronsfromtheacetylportionofacetylCoAtoNAD+andFAD

Thesynthesisofglucosefrompyruvatebygluconeogenesis:

参考答案:

requirestheparticipationofbiotin.

TheuniquepathwayformatureredbloodcellstoobtainATPis

参考答案:

glycolysis

What

is

the

consequence

of

thermalgenin

effect.

参考答案:

Producingmoreheat

Whichcoenzymeinpyruvatedehydrogenasecomplexservesasthefinalhydrogensacceptor?

参考答案:

NAD+

Whichenzymeisthekeyenzymeinglycogenolysis(glycogendegradation)?

参考答案:

Phosphorylase

WhichoffollowingsubunitismainlyresponsibletocatalyzethesynthesisofATPinATPsynthase?

参考答案:

β

Whichofthefollowingglycolyticenzymesisusedingluconeogenesis?

参考答案:

Aldolase

Whichofthefollowingmetabolicpathwaytakeplaceinthemitochondira?

参考答案:

thesynthesisofketonebody

WhichofthefollowingstatementsaboutglycolysisisTRUE?

参考答案:

Glucokinasecatalyzestheconversionofglucosetoglucose6-phosphateintheliver

WhichoneofthefollowingisaconditiondecreasedtheoxidationofacetylCoAbythecitricacidcycle?

参考答案:

AlowNAD+/NADHratio

Whichoneofthefollowingstatementsconcerningglycolysisiscorrect?

参考答案:

Therate-limitingreactionsarealsotheirreversiblereaction.

三聚氰胺奶粉提高蛋白质浓度的机理是什么？

参考答案:

504GatewayTime-out504GatewayTime-outnginx

下列化合物中除()外都是呼吸链的组成成分。

参考答案:

CoA

为什么对于乙肝患者治疗策略之一是大剂量补充复合维生素？

参考答案:

504GatewayTime-out504GatewayTime-outnginx

为什么摄入过多的果糖能够导致脂肪肝？

参考答案:

.

举例说明蛋白质变性在生活中的应用

参考答案:

504GatewayTime-out504GatewayTime-outnginx

举例说明酶的抑制剂在医学中的应用。

参考答案:

504GatewayTime-out504GatewayTime-outnginx

什么原因可以导致低血糖？

参考答案:

.

以构象病（任一种）为例说明蛋白结构和功能的关系。