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2022-2023年浙江省舟山市公共英语五级(笔试)真题一卷(含答案)学校:________班级:________姓名:________考号:________

一、1.ListeningComprehension(15题)1.Whatisthecharacteristicofspecialtygoods?

A.Theyaregoodsthatcanbeboughtataspecialprice.

B.Theyarespecialkindsofproducts.

C.Theyarecharacterizedintheirbrands.

D.Theyneedspecialeffortstoget.

2.PartC

Directions:Youwillhearatalk.Asyoulisten,answerthequestionsorcompletethenotesinyourtestbookletforQuestions21-30bywritingNOTMORETHANTHREEwordsinthespaceprovidedontheright.YouwillhearthetalkTWICE.

Younowhave1minutetoreadQuestions21-30.

听力原文:ForthoseofyouwhoareeitheralreadystudyingintheUnitedStatesorplanningtooneday,itmightbeinterestingtoknowsomethingabouttheforeignstudentpopulationintheUnitedStates.Fortheacademicyear1995/96therewasasumofapproximately344,000foreignstudentsstudyingintheUnitedStates.Thisfigureof344000mayseemlikeaverylargenumberuntilyoucompareitwiththetotalpopulationof241,000,000.Theforeignstudentpopulationhasbeengrowingforanumberofyearsandisstillgrowing,buttherateofincreasehasdroppedsharplyduringthe1990s.Duringthe1980s,thepopulationgrewquiterapidly.Forexample,between1985and1990.theaverageyearlyincreasewas12.5%.However,thepictureinthe1990sisquitedifferent.Therateofincreasehasdeclinedquitenoticeably.Infact,therateofincreasebetween1994/95and1995/96wasonly0.5%,orone-halfofonepercent.Althoughtheoverallrateofincreasehasdroppedtoonly0.5%.thenumberofstudentsfromsomepartsoftheworldisincreasingwhilethenumberofstudentsfromotherareasisdecreasing.Forexample,duringthissameperiod,thatisbetweentheacademicyears1994/95and1995/96,therewasadecreaseinthenumberofstudentsfromtheMiddleEast,whilethenumberofstudentsfromSouthandEastAsiaincreased.Thesechangesinthenumberofstudentscomingfromdifferentpartsoftheworldnodoubtreflectedchangingeconomicandpoliticalsituations.I'msureyouareawareofmanyofthesechanges,andperhapswecandiscussthematournextmeeting.Fortodaylet'sconfineourtalktofirst,adiscussionoftheoriginofthesestudents,or,inotherwords,wheretheycamefrom;second,thekindsofstudiestheypursue;and,finally,theacademiclevelstheyarefoundin.Ifwehavealittletimeleft,wemightquicklytalkaboutinwhichgeographicareasmostofthemgotoschool.

Let'sdiscusstheoriginsoftheforeignstudentpopulationintheUnitedStatesfortheacademicyear1995/96.Let'sdiscussitinorderfromthoseareassendingthemoststudentstothoseareassendingthefeweststudents.IfwelookatthefiguresprovidedbytheannualcensusofforeignstudentsintheUnitedStatesfortheyear1995/96,weseethatmostoftheforeignstudentsstudyingintheUnitedStatesduringthisyearwerefromSouthandEastAsia.ThisisaratherlargegeographicalareawhichincludessuchconutriesasChina,Korea,Pakistan,India,Malaysia,andIndonesia.Thetotalnumberofstudentsfromthisarea,SouthandEastAsiawas156,830.Inotherwords,roughly2outofevery5foreignstudentscomefromSouthandEastAsia.Almost24000ofthistotalwerefromChina.Malaysiawasclosebehindwithjustalittleover23000students.ThenextlargestnumberofstudentscamefromtheMiddleEast.ThenumberofstudentsfromtheMiddleEastcametoaboutone-thirdthenumberfromSouthandEastAsia.ThefourthlargestnumbercamefromSouthAmerica.NextcanleEurope,Africa,NorthAmerica,andOceania.Let'srecapitulatewhatwe'vesaid.ThelargestnumberofstudentsstudyingintheUnitedStatesduringtheacademicyear1995/96werefromSouthandEastAsia,followedbytheMiddleEast,SouthAmerica,Europe,Africa,NorthAmerica,andOceania.

Whatfieldsaretheselargenumbersofforeignstudentsstudyingin?Itprobablywon'tsurpriseyouthatthelargestnumberareinthefieldofengineering.Infact,21.7%ofthetotalnumberarestudyingengineering.Businessandmanagementisclosebehind,however,withatotalof18.9%.Thethirdmostpopularfieldwasmathematicsand

3.Theystartedworkingin1968basedontheobservationmadebyJung,thefounderof______.

4.Youcanfindyournoseinthedarknessbecauseofyour"feltimage".

A.TrueB.Fasle

5.StudyinginanEnglish-speakingcountryisaveryeffectivewaytolearnEnglish.

A.TrueB.Fasle

6.Chainsdon'tproducetheirowncoursebookmaterial.

A.RightB.Wrong

7.Shiraliprobablyliveduntil168;Tsurbaprobablyliveduntilage160.

A.TrueB.Fasle

8.Ourhumanfriendssometimesmaymakeusbored,butthefriendsinbooksmayalsobehurtbyus.

A.TrueB.Fasle

9.Thepossibilitiesofourliteraryexperiencesarealmostunlimited.

A.TrueB.Fasle

10.PartC

Directions:Youwillhearatalk.Asyoulisten,answerthequestionsorcompletethenotesinyourtestbookletforQuestions21-30bywritingNOTMORETHANTHREEwordsinthespaceprovidedontheright.YouwillhearthetalkTWICE.

Younowhave1minutetoreadQuestions21-30.

听力原文:ForthoseofyouwhoareeitheralreadystudyingintheUnitedStatesorplanningtooneday,itmightbeinterestingtoknowsomethingabouttheforeignstudentpopulationintheUnitedStates.Fortheacademicyear1995/96therewasasumofapproximately344,000foreignstudentsstudyingintheUnitedStates.Thisfigureof344000mayseemlikeaverylargenumberuntilyoucompareitwiththetotalpopulationof241,000,000.Theforeignstudentpopulationhasbeengrowingforanumberofyearsandisstillgrowing,buttherateofincreasehasdroppedsharplyduringthe1990s.Duringthe1980s,thepopulationgrewquiterapidly.Forexample,between1985and1990,theaverageyearlyincreasewas12.5%.However,thepictureinthe1990sisquitedifferent.Therateofincreasehasdeclinedquitenoticeably.Infact,therateofincreasebetween1994/95and1995/96wasonly0.5%,orone-halfofonepercent.Althoughtheoverallrateofincreasehasdroppedtoonly0.5%,thenumberofstudentsfromsomepartsoftheworldisincreasingwhilethenumberofstudentsfromotherareasisdecreasing.Forexample,duringthissameperiod,thatisbetweentheacademicyears1994/95and1995/96,therewasadecreaseinthenumberofstudentsfromtheMiddleEast,whilethenumberofstudentsfromSouthandEastAsiaincreased.Thesechangesinthenumberofstudentscomingfromdifferentpartsoftheworldnodoubtreflectedchangingeconomicandpoliticalsituations.I'msureyouareawareofmanyofthesechanges,andperhapsyoucandiscussthematournextmeeting.Fortodaylet'sconfineourtalktofirst,adiscussionoftheoriginofthesestudents,or,inotherwords,wheretheycamefromsecond,thekindsofstudiestheypursue;and,finally,theacademiclevelstheyarefoundin.Ifwehavealittletimeleft,wemightquicklytalkaboutinwhichgeographicareasmostofthemgotoschool.

Let'sdiscusstheoriginsoftheforeignstudentpopulationintheUnitedStatesfortheacademicyear1995/96.Let'sdiscussitinorderfromthoseareassendingthemoststudentstothoseareassendingthefeweststudents.IfwelookatthefiguresprovidedbytheannualcensusofforeignstudentsintheUnitedStatesfortheyear1995/96,weseethatmostoftheforeignstudentsstudyingintheUnitedStatesduringthisyearwerefromSouthandEastAsia.Thisisaratherlargegeographicalareawhichincludessuchconu-triesasChina,Korea,Pakistan,India,Malaysia,andIndonesia.Thetotalnumberofstudentsfromthisarea,SouthandEastAsiawas156,830.Inotherwords,roughly2outofevery5foreignstudentscomefromSouthandEastAsia.Almost24000ofthistotalwerefromChina.Malaysiawasclosebehindwithjustalittleover23000students.ThenextlargestnumberofstudentscamefromtheMiddleEast.ThenumberofstudentsfromtheMiddleEastcametoaboutone-thirdthenumberfromSouthandEastAsia.ThefourthlargestnumbercamefromSouthAmerica.NextcameEurope,Africa,NorthAmerica,andOceania.Let'srecapitulatewhatwe'vesaid.ThelargestnumberofstudentsstudyingintheUnitedStatesduringtheacademicyear1995/96werefromSouthandEastAsia,followedbytheMiddleEast,SouthAmerica,Europe,Africa,NorthAmerica,andOceania.

Whatfieldsaretheselargenumbersofforeignstudentsstudyingin?Itprobablywon'tsurpriseyouthatthelargestnumberareinthefieldofengineering.Infact,21.7%ofthetotalnumberarestudyingengineering.Businessandmanagementisclosebehind,however,withatotalof18.9%.Thethirdmostpopularfieldw

11.Do-it-YourselfhasbecomeoneofMr.Miller'shobbies.

A.TrueB.Fasle

12.听力原文:Now,letmefirstgiveyouabriefintroductiontotheAmericanpoet,EmilyDickinson.EmilyDickinsonwasAmerica'sbest-knownfemalepoetandoneoftheforemostauthorsinAmericanliterature.BorninAmherst,Massachusetts,Dickinsonwasthemiddlechildofaprominentlawyerandone-termUnitedStatescongressionalrepresentative,EdwardDickinson,andhiswife.EmilyNorcrossDickinson.From1840to1847sheattendedtheAmherstAcademy.andfrom1847to1848shestudiedattheMountHolyokeFemaleSeminary(nowMountHolyokeCollege)inSouthHadley,afewtripstoBostonforeyetreatmentsintheearly1860s。DickinsonremainedinAmherst.livinginthesamehouseonMainStreetfrom1855untilherdeath.Duringherlifetime,shepublishedonlyabout10ofhernearly2,000poems,innewspapers,Civilwarjournais,andapoetryanthology.ThefirstvolumeofPoemsofEmilyDickinsonwaspublishedin1890,afterDickinson'sdeath.

AlthoughfewofDickinson'spoemswereformallypublishedduringherlifetime,sheherself“published”bysendingoutatleastone-thirdofherpoemsinthemorethan1,000lettersshewrotetoatleast100differentcorrespondents.Dickinson'smethodofbindingabout800ofherpoemsinto40manuscript.booksanddistributingseveralhundredoftheminlettersisnowwidelyrecognizedasherparticularform.ofself-publication.Shealsoreadherpoemsaloudtoseveralpeople,includinghercousinsLouiseandFrancesNorcross,overaperiodofthreedecades.

Well.that'sallaboutherlife.Nowshallweconcentrateonherfamouspoem,“SuccessisCountedSweetest”.

InwhichstatewasEmilyDicksonborn?

A.Michigan.B.Ohio.C.Massachusetts.D.Washington.

13.Sugarincoldsweetdrinksslowstheliquidfromgettingintotheblood-stream.

A.TrueB.Fasle

14.WhatwaspotatousedforinEuropeatfirst?

15.Strokevictimssometimesrefusetoregardtheirinjuredsidesaspartsoftheirbodiesbecausetheyareunwillingtoadmittheirdisabilities.

A.RightB.Wrong

二、2.UseofEnglish(10题)16.

【C9】

17.

【C8】

18.(47)

19.(48)

20.

【C10】

21.Psychologiststakecontrastiveviewsofhowexternalrewards,from【31】______praisetocoldcash,affectmotivationandcreativity.Behaviorists,【32】______researchtherelation【33】______actionsandtheirconsequencesarguethatrewardscanimproveperformanceatworkandschool.Cognitiveresearchers,whostudyvariousaspectsofmentallife,maintain【34】______rewardsoftendestroycreativity【35】______encouragingdependence【36】______approvalandgiftsfromothers.

Thelatterviewhasgainedmanysupporters,especially【37】______educators.Butthecarefuluseofsmallmonetaryrewardssparks【38】______ingrade-schoolchildren,suggesting【39】______properlypresentedinducementsindeedaidinventiveness,【40】______toastudyintheJuneJournalofPersonalityandSocialPsychology"Ifkidsknowthey'reworkingfora【41】______andcanfocus【42】______arelativelychallengingtask,theyshowthemostcreativity",saysRobertEisenbergeroftheUniversityofDelawareinNewark."Butit'seasytokillcreativitybygivingrewardsfor【43】______performanceorcreatingtoo【44】______anticipationforrewards."

Ateacher【45】______continuallydrawsattentiontorewardsorwhohands【46】______highgradesforordinaryachievementendsup【47】______discouragedstudents,Eisenbergerholds.【48】______anexampleofthelatterpoint,henotesgrowingeffortsatmajoruniversitiestotightengradingstandardsandrestorefailing【49】Inearliergrades,theuseofso-calledtokeneconomies,in【50】______studentshandlechallengingproblemsandreceiveperformance-basedpointstowardvaluedrewards,showspromiseinraisingeffortandcreativity,theDelawarepsychologistclaims.

(31)

22.

【C5】

23.(43)

24.

【C6】

25.(32)

三、3.ReadingComprehension(15题)26.

______isalongwithmanycomparativelysmallbuildingsoneitherside?

27.Beforeabigexam,asoundnight'ssleepwilldoyoubetterthanporingovertextbooks.That,atleast,isthefolkwisdom.Andscience,intheform.ofbehavioralpsychology,supportsthatwisdom.Butsuchbehavioralstudiescannotdistinguishbetweentwocompetingtheoriesofwhysleepisgoodforthememory.Onesaysthatsleepiswhenpermanentmemoriesform.Theothersaysthattheyareactuallyformedduringtheday,butthen"edited"atnight,toflushawaywhatissuperfluous.

Totellthedifference,itisnecessarytolookintothebrainofasleepingperson,andthatishard.Butafteradecadeofpainstakingwork,ateamledbyPierreMaquetatLiegeUniversityinBelgiumhasmanagedtodoit.TheparticularstageofsleepinwhichtheBelgiangroupisinterestedisrapideyemovement(REM)sleep,whenbrainandbodyareactive,heartrateandbloodpressureincrease,theeyesmovebackandforthbehindtheeyelidsasifwatchingamovie,andbrainwavetracesresemblethoseofwakefulness.Itisduringthisperiodofsleepthatpeoplearemostlikelytoreliveeventsofthepreviousdayindreams.

Dr.MaquetusedanelectronicdevicecalledPETtostudythebrainsofpeopleastheypracticedataskduringtheday,andastheysleptduringthefollowingnight.Thetaskrequiredthemtopressabuttonasfastaspossible,inresponsetoalightcomingoninoneofsixpositions.Astheylearnthowtodothis,theirresponsetimesgotfaster.Whattheydidnotknowwasthattheappearanceofthelightssometimesfollowedapattern—whatisreferredtoas"artificialgrammar".Yetthereductionsinresponsetimeshowedthattheylearntfasterwhenthepatternwaspresentthanwhentherewasnot.

Whatismore,thosewithmoretolearn(i.e.the"grammar",aswellasthemechanicaltaskofpushingthebutton)havemoreactivebrains.The"editing"theorywouldnotpredictthat,sincethenumberofirrelevantstimuliwouldbethesameineachcase.Andtoeliminateanydoubtsthattheexperimentalsubjectswerelearningasopposedtounlearning,theirresponsetimeswhentheywokeupwereevenquickerthanwhentheywenttosleep.

Theteam,therefore,concludedthatthenerveconnectionsinvolvedinmemoryarereinforcedthroughreactivationduringREMsleep,particularlyifthebraindetectsaninherentstructureinthematerialbeinglearnt.Sonow,ontheeveofthatcrucialtest,mathsstudentscansleepsoundlyintheknowledgethatwhattheywillrememberthenextdayarethebasicrulesofalgebraandnottheincoherenttalkfromtheradionextdoor.

Researchersinbehavioralpsychologyaredividedwithregardto______.

A.howdreamsaremodifiedintheircourses

B.thedifferencebetweensleepandwakefulness

C.whysleepisofgreatbenefittomemory

D.thefunctionsofagoodnight'ssleep

28.

Accordingtothepassage,whichofthefollowingisnottrue?

A.SomeAmericanswouldnotacceptthevalueofconservationandenvironmentprotection,becausethisvaluewouldprobablymakethemunemployed.

B.ManyAmericanshavebeenusedtowasting,soitwillbedifficultforthemtoacceptthenewvalueofconservation.

C.SomeoldvaluesarestillhavingaverystronginfluenceonAmericanpeople,althoughtheyareharmfulinthisnewage.

D.MostAmericanshavefullyrealizedtheneedtoprotecttheenvironment,sotheyhavetakenmeasurestorecyclejunkedgoods.

29.PartC

Directions:Answerquestions71-80byreferringtothefollowinggames.

Note:AnswereachquestionbychoosingA,BorCandmarkitonANSWERSHEET1.Somechoicesmayberequiredmorethanonce.

A=TheImperialPalaceB=TheTempleofHeavenC=PotalaPalaceD=JokhangTempleWhichpalaceortemple...

isthespiritualcenterofTibet?71.______

iscircularinthenorthernpartwhilesquareinthesouthernpart?72.______

presentsthelargestandmostcompleteensembleoftraditionalarchitecture?73.______

coversabuildingspaceof90thousandsquaremeters?74.______

istheoldestoneamongthefourinthetext?75.______

canpresentthevisitorthesignificanceofHeavenKitchen?76.______

isacombinationofarchitecturalstylesfromHan,TibetanandNepalese?77.______

wasthereligiousandpoliticalcenterofoldTibet?78.______

isalongwithmanycomparativelysmallbuildingsoneitherside?79.______

presentsanedictsignedwiththeGreatFifth'shandprint?80.______

A

TheImperialPalace

Whatstrikesonefirstinabirds-eyeviewofBeijingproperisavasttractofgoldenroofsflashingbrilliantlyinthesunwithpurplewallsoccasionallyemergingamidthemandastretchofluxurianttreeleavesflankingoneachside.ThatistheformerImperialPalace,popularlyknownastheForbiddenCity,fromwhichtwenty-fouremperorsoftheMingandQingDynastiesruledChinaforsome500years—from1420to1911.TheMingEmperorYongLe,whousurpedthethronefromhisnephewandmadeBeijingthecapital,ordereditsconstruction,onwhichapproximately10,000artistsandamillionworkmentoiledfor14yearsfrom1406to1420.Atpresent,thePalaceisanelaboratemuseumthatpresentsthelargestandmostcompleteensembleoftraditionalarchitecturecomplexandmorethan900,000piecesofcourttreasuresinalldynastiesinChina.

LocatedinthecenterofBeijing,theentirepalacearea,rectangularinshapeand72hectaresinsize,issurroundedbywallstenmetershighandamoat52meterswide.Ateachcornerofthewallstandsawatchtowerwithadouble-eaveroofcoveredwithyellowglazedtiles.

Themainbuildings,thesixgreathalls,onefollowingtheother,aresetfacingsouthalongthecentralnorth-southaxisfromtheMeridianGate,thesouthentrance,toShenwumen,thegreatgatepiercinginthenorthwall.Oneithersideofthepalacearemanycomparativelysmallbuildings.SymmetricallyinthenortheasternsectionliethesixEasternPalacesandinthenorthwesternsectionthesixWesternPalaces.ThePalaceareaisdividedintotwoparts:theOuterCourtandtheInnerPalace.Theformerconsistsofthefirstthreemainhalls,wheretheemperorreceivedhiscourtiersandconductedgrandceremonies,whilethelatterwasthelivingquartersfortheimperialresidence.AttherearoftheInnerPalaceistheImperialGardenwheretheemperorandhisfamilysoughtrecreation.

B

TheTempleofHeaven

TheTempleofHeavenwasinitiallybuiltinYongleYear18oftheMingDynasty(in1420).Situatedinthesouthernpartofthecity,itcoversthetotalareaof273hectares.WiththeadditionsandrebuildingduringtheMing,QingandotherDynasties,thisgrandsetofstructureslookmagnificentandglorious;thedignifiedenvironmentappearssolemnandrespectful.ItistheplaceforbothMingandQingDynasty'sEmperorstoworshipHeavenandprayforgoodharve

30.

Whycanmanypeoplesee“silverlinings”totheeconomicshowdown?

A.Theywouldbenefitincertainways.

B.Thestockmarketshowssignsofrecovery.

C.Suchaslowdownusuallyprecedesaboom.

D.Thepurchasingpowerwouldbeenhanced.

31.Themanbehindthisnotion,JackMaple,isadandywhoaffectsdarkglasses,homburgs(翘边帽)andtwo-toeshoes;yethehasbecomesomethingofalegendinAmerica'spolicedepartments.Forsomeyears,startinginNewYorkandmovingontohigh-crimespotssuchasNewOrleansandPhiladelphia,heandhisbusinesspartner,JohnLinderhavemarketedatwo-tiersystemforcuttingcrime.

First,policedepartmentshavetosortthemselvesout:rootoutcorruption,streamlinetheirbureaucracy,andmakemorecontactwiththepublic.Second,theyhavetoadoptacomputersystemcalledComstatwhichhelpsthemtoanalyzestatisticsofallmajorcrimes.Theseareconstantlykeyedintothecomputer,whichthendisplayswhereandwhentheyhaveoccurredonacolor-codedmap,enablingthepolicetomonitorcrimetrendsastheyhappenandtospothigh-crimeareas.InNewYork,Comstat'sstatisticalmapsareanalyzedeachweekatameetingofthecity'spolicechiefandprecinctcaptains.

MessrsMapleandLinder("specialistsincrime-reductionservices")havenodoubtthattheirsystemisamaincontributortothedropincrime.WhentheyintroduceditinNewOrleansinJanuary1997,violentcrimedroppedby22%inayear;whentheymerelystartedworkinginformallywiththepolicedepartmentinNewark,NewJersey,violentcrimefellby13%.Policedepartmentsarenowlininguptopayasmuchas$50,000amonthforthesetwomentoputthemstraight.

Probablyallthesenewpoliciesandbitsoftechnicalwizardry,addedtogether,havemadeabigdifferencetocrime.Butthereremainanomaliesthatcannotbeexplained,suchasthefactthatcrimeinWashingtonD.C.,hasfallenasfastasanywhere,althoughthepolicedepartmenthasbeencorruptandhopelessand,inlargestretchesofthecity,neitherpolicenorresidentsseemdisposedtofightthecriminalsintheirmidst.

Themoreimportantreasonforthefallincrimerates,manysay,isamuchlesssophisticatedone.Itisafactthatcrimerateshavedroppedastheimprisonmentratesoared.In1997thenationalincarcerationrate,at645per100000peoplewasmorethandoubletheratein1985,andthenumberofinmatesincityandcountyjailsroseby9.4%.almostdoubleitsannualaverageincreasesince1990.Surelysomecriminologistsargue,onesetoffiguresisthecauseoftheother.Itisprecisebecausemorepeoplearebeingsenttoprison,theyclaimthatcrimeratesarefalling.A1993studybytheNationalAcademyofSciencesactuallyconcludedthatthetriplingoftheprisonpopulationbetween1975and1989hadloweredviolentcrimeby10-15%.

Yetcauseandeffectmaynotbesoobviouslylinked.Tobeginwith,thesaleandpossessionofdrugsarenotcountedbytheFBIinitscrimeindex,whichislimitedtoviolentcrimesandcrimesagainstproperty.Yetdrugoffencesaccountformorethanathirdoftherecentincreaseinthenumberofthosejailed;since1980,theincarcerationratefordrugarrestshasincreasedby1000%.Andalthoughaboutthree-quartersofthosegoingtoprisonfordrugoffenceshavecommittedothercrimesaswell,thereisnotyetacrystal-clearconnectionbetweenfillingthejailswithdrug-pushersandadeclineintherateofviolentcrime.Again,thoughnationalfiguresaresuggestive,localonesdiverge:theplaceswherecrimehasdroppedmostsharply(suchasNewYorkCity)arenotalwaystheplaceswhereincarcerationhasrisenfastest.

JackMaplestartedhiscareerin______.

A.PhiladelphiaB.OregonC.NewOrleansD.NewYork

32.(73)

33.At18,AshanthiDeSilvaofsuburbanClevelandisalivingsymbolofoneofthegreatintellectualachievementsofthe20thcentury.Bornwithanextremelyrareandusuallyfataldisorderthatleftherwithoutafunctioningimmunesystem(the"bubble-boydisease",namedafteranearliervictimwhowaskeptaliveforyearsinasterileplastictent),shewastreatedbeginningin1990witharevolutionarynewtherapythatsoughttocorrectthedefectatitsverysource,inthegenesofherwhitebloodcells.Itworked.Althoughherlastgene-therapytreatmentwasin1992,sheiscompletelyhealthywithnormalimmunefunction,accordingtooneofthedoctorswhotreatedher,W.FrenchAndersonoftheUniversityofSouthernCalifornia.Researchershavelongdreamedoftreatingdiseasesfromhemophiliatocancerbyreplacingmutantgeneswithnormalones.Andthedreamingmaycontinuefordecadesmore."Therewillbeagene-basedtreatmentforessentiallyeverydisease,"Andersonsays,"within50years."

It'snotentirelyclearwhymedicinehasbeensoslowtobuildonAnderson'searlysuccess.TheNationalInstitutesofHealthbudgetofficeestimatesitwillspend$432millionongene-therapyresearchin2005,andthereisnoshortageofpromisingleads.Thetherapeuticgenesareusuallydeliveredthroughvirusesthatdon'tcausehumandisease."ThevirusissortoflikeaTrojanhorse,"saysRonaldCrystalofNewYorkPresbyterian/WeillCornellMedicalCollege."Thecargoisthegene."

AttheUniversityofPennsylvania'sAbramsohCancerCenter,immunologistCarlJunerecentlytreatedHIVpatientswithageneintendedtohelptheircellsresisttheinfection.AtCornellUniversity,researchersarepursuinggene-basedtherapiesforParkinson'sdiseaseandararehereditarydisorderthatdestroyschildren'sbraincells.AtStanfordUniversityandtheChildren'sHospitalofPhiladelphia,researchersaretryingtofigureouthowtohelppatientswithhemophiliawhotodaymustinjectthemselveswithexpensiveclottingdrugsforlife.Animalexperimentshaveshowngreatpromise.

Butsomehow,thingsgetlostinthetranslationfromlaboratorytopatient.Inhumantrialsofthehemophiliatreatment,patientsshowaresponseatfirst,butitfadesovertime.Andthefieldhasstillnotrecoveredfromthesetbackitsufferedin1999,whenJesseGelsinger,an18-year-oldwithararemetabolicdisorder,diedafterreceivinganexperimentalgenetherapyattheUniversityofPennsylvania.Someexpertsworrythatthefieldwillbetarnishedfurtherifthenextpeopletobenefitarenotpatientsbutathletesseekinganedge.Thissummer,researchersattheSalkInstituteinSanDiegosaidtheyhadcreateda"marathonmouse"byimplantingagenethatenhancesrunningability;already,officialsattheWorldAnti-DopingAgencyarepreparingtotestathletesforsignsof"genedoping".Buttheprincipleisthesame,whetheryou'retryingtohelpahealthyrunnerrunfasterorallowamuscular-dystrophypatienttowalk."Everybodyrecognizesthatgenetherapyisaverygoodidea,"saysCrystal."Andeventuallyit'sgoingtowork."

ThecaseofAshanthiDesilvaismentionedinthetextto______.

A.showthepromiseofgene-therapy

B.giveanexampleofmoderntreatmentforfataldiseases

C.introducethea

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