流行病学课件2014级临床from6实验研究

医生JamesLind同

服用大蒜、芥末籽、玄参素、秘鲁香液和没药树脂

JamesLind(1716-VitC随机

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随随机 组组

随机随访 施后，随访并比较两组人群的发病()情况或随机 群组

clinicaltrial,(true(true对照干预前瞻

分 析 性 研 究检验假设能力检验假设能力 (true(true(true(clinical（randomizedcontrolledtrial/randomizedclinical(clinical

Populationofpatientsasdefinedbyeligibilitycriteria(populationP)(sampleA)Formalentrytotrial(patientsagreeingtoparticipate:sampleB)

Eligiblepatientswho,forsomereason,werenotenteredinthetrial(oftenrefusedTreatmentgroup Treatmentgroup (样本

符合诊断标准的因(不同意参与试验) 合格人群(apopulationofeligible （agroupofpatientsrecruitedfromthispopulation)least)twotreatmentgroups)isbyrandomization) emeasuresinthetreatmentgroupsarecomparedattheendofthe设立同期对照（theneedforconcurrent随机分配(allocationat ： P P：2 2 (1-EpiCalcEpiCalcEpiCalc：2(ZZ)2： d(1-EpiCalcEpiCalc设立同期对照（theneedforconcurrent随机分配(allocationat（theneedforconcurrent （theneedforconcurrent （theneedforconcurrent 123（theneedforconcurrent （theneedforconcurrent cebo–1958手术治疗502-6 对照设置的问题益，如果对照组不给予治疗，就存在学问题，因此 Obstructivecoronary Excimerlasercoronary Balloonangio arterydisease (Appelmanet 准分子激光冠状动脉血气球扩张血管成形(cockburnetal.,Diabetesmellitusinchildhoodandal.,1989)

Specialeducationclassesinadditiontousualclinicvisits

cebousualclinicvisits设立同期对照（theneedforconcurrent随机分配(allocationatAllocationat AllocationatAllocationatAllocationat

Allocationat、AllocationatAllocationat设立同期对照（theneedforconcurrent随机分配(allocationat

检查的频度； 讲可以完全消除各方面的因素，避免了常复杂，几乎难以实现。

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