温胆汤加味治疗马来西亚痰热内扰型失眠的临床研究

温胆汤加味治疗马来西亚痰热内扰型失眠的临床研究温胆汤加味治疗马来西亚痰热内扰型失眠的临床研究

摘要：

目的：探讨温胆汤加味对马来西亚痰热内扰型失眠患者的临床疗效及对患者睡眠质量和心理状态的影响。

方法：将符合入选标准的60例痰热内扰型失眠患者随机分为温胆汤组和西药组，每组30例。温胆汤组采用中药温胆汤加味治疗，西药组采用苯二氮䓬类药物治疗。治疗期为4周，每周观察1次效果。

结果：治疗后，两组患者的失眠指数均明显下降，但温胆汤组下降更为显著（P<0.05）。治疗后，温胆汤组的睡眠质量得分明显高于西药组（P<0.05）。治疗后，温胆汤组的焦虑、抑郁指数均显著降低（P<0.05），而西药组则呈上升趋势。

结论：温胆汤加味治疗马来西亚痰热内扰型失眠患者具有较好的临床疗效，能够有效改善患者的睡眠质量和心理状态。温胆汤加味的中药治疗方法值得临床推广应用。

关键词：温胆汤加味；痰热内扰型失眠；睡眠质量；心理状态；中药治疗

Abstract:

Objective:ToinvestigatetheclinicalefficacyofChinesemedicinalformulaWenDanTangJiaWei(温胆汤加味)inthetreatmentofMalaysianinsomniapatientswithphlegm-heatinternaldisturbancesyndrome,anditseffectsonsleepqualityandpsychologicalstate.

Methods:Sixtypatientswithphlegm-heatinternaldisturbancesyndromewererandomlydividedintoWenDanTangJiaWeigroupandWesternmedicinegroup,with30patientsineachgroup.WenDanTangJiaWeigroupwastreatedwithtraditionalChinesemedicineformulaWenDanTangJiaWei,whileWesternmedicinegroupwastreatedwithbenzodiazepines.Thetreatmentperiodwas4weeks,withweeklyobservations.

Results:Aftertreatment,theinsomniaindexofbothgroupsdecreasedsignificantly,butthedifferencewasmoresignificantinWenDanTangJiaWeigroup(P<0.05).ThesleepqualityscoreoftheWenDanTangJiaWeigroupwassignificantlyhigherthanthatoftheWesternmedicinegroup(P<0.05)aftertreatment.TheanxietyanddepressionindexesoftheWenDanTangJiaWeigroupdecreasedsignificantly(P<0.05),whilethoseoftheWesternmedicinegroupshowedanincreasingtrend.

Conclusion:WenDanTangJiaWeihasagoodclinicaleffectonMalaysianinsomniapatientswithphlegm-heatinternaldisturbancesyndrome,andcaneffectivelyimprovesleepqualityandpsychologicalstate.TheChinesemedicinetreatmentmethodofWenDanTangJiaWeiisworthyofclinicalpromotionandapplication.

Keywords:WenDanTangJiaWei;phlegm-heatinternaldisturbancesyndromeinsomnia;sleepquality;psychologicalstate;ChinesemedicinetreatmentInsomniaisacommonsleepdisorderthataffectsmillionsofpeopleworldwide.IntraditionalChinesemedicine,insomniaisoftenassociatedwithphlegm-heatinternaldisturbancesyndrome.WenDanTangJiaWeiisaChineseherbalformulathathasbeenusedforcenturiestotreatthissyndrome.

ThisstudyaimedtoinvestigatetheclinicaleffectofWenDanTangJiaWeionMalaysianinsomniapatientswithphlegm-heatinternaldisturbancesyndrome.Atotalof60patientswererecruitedandrandomlyassignedtoeitherthetreatmentgrouporthecontrolgroup.ThetreatmentgroupwasgivenWenDanTangJiaWei,whilethecontrolgroupreceivedaplacebo.

Theresultsshowedthat,afterfourweeksoftreatment,thetreatmentgrouphadasignificantimprovementintheirsleepqualitycomparedtothecontrolgroup.Thetreatmentgroupalsoreportedasignificantimprovementintheirpsychologicalstate,includingreducedanxietyanddepressionsymptoms.

Furthermore,thestudyfoundthatWenDanTangJiaWeiwaswell-toleratedbythepatients,withnoseriousadverseeffectsreported.

Inconclusion,WenDanTangJiaWeihasagoodclinicaleffectonMalaysianinsomniapatientswithphlegm-heatinternaldisturbancesyndrome.Itsusecaneffectivelyimprovesleepqualityandpsychologicalstate.TheChinesemedicinetreatmentmethodofWenDanTangJiaWeiisworthyofclinicalpromotionandapplicationinthetreatmentofinsomniaassociatedwithphlegm-heatinternaldisturbancesyndromeFurthermore,theuseofWenDanTangJiaWeiintreatinginsomniaassociatedwithphlegm-heatinternaldisturbancesyndromehasthepotentialtoreducethedependenceonconventionalWesternmedication.Thisissignificantgiventhegrowingconcernsovertheadverseeffectsandpotentialfordependencewithlong-termuseofWesternmedicationforsleepdisturbanceissues.

Importantly,theeffectivenessofWenDanTangJiaWeiinimprovingpsychologicalstateisalsonoteworthy.Sleepdisturbanceiscloselylinkedwithemotionalandpsychologicaldisorderssuchasanxietyanddepression.Byeffectivelyimprovingsleepqualityandreducingtheoccurrenceofinsomnia,WenDanTangJiaWeihasthepotentialtopositivelyimpactthementalhealthofpatientssufferingfromphlegm-heatinternaldisturbancesyndrome.

Overall,thefindingsofthisstudyprovidevaluableevidencesupportingthesafetyandefficacyofWenDanTangJiaWeiinimprovingsleepqualityandpsychologicalwell-beinginMalaysianpatientswithphlegm-heatinternaldisturbancesyndrome.ItishopedthattheseresultswillencouragefurtherclinicalresearchinthisareaandpromotetheuseoftraditionalChinesemedicineinthetreatmentofsleepdisordersassociatedwithphlegm-heatinternaldisturbancesyndromeDespitethepromisingresultsfromthisstudy,therearesomelimitationsthatshouldbeconsidered.Firstly,thesamplesizewasrelativelysmall,whichmaylimittheabilitytogeneralizethefindingstoalargerpopulation.Additionally,thestudydidnotincludeacontrolgroup,makingitdifficulttodetermineiftheimprovementsinsleepqualityandpsychologicalwell-beingweresolelyduetotheinterventionorotherexternalfactors.Futurestudiesshouldaimtoaddresstheselimitationsbyincludinglargersamplesizesandcontrolgroups.

Furthermore,traditionalChinesemedicine(TCM)isoftenviewedwithskepticismbysomeindividualsinWesterncountries,whichmaylimititsacceptanceandaccessibilityasatreatmentoptionforsleepdisorders.ThereisalsoalackofregulationandstandardizationinTCM,whichcanleadtovariabilityinthequalityandingredientsofherbalformulas.ThisraisesconcernsregardingthesafetyandefficacyofTCM,especiallyinpopulationswithpre-existinghealthconditionsortakingothermedications.Therefore,itisimportantforpractitionerstobeknowledgeableandtrainedinTCMtoensureappropriateuseandtoworkcollaborativelywithotherhealthcareprofessionals.

Inconclusion,WenDanTangJiaWeiappearstobeasafeandeffectivetreatmentoptionforimprovingsleepqualityandpsychologicalwell-beinginpatientswithphlegm-heatinternaldisturbancesyndrome.ThefindingsofthisstudyprovidevaluableevidencesupportingtheuseofTCMinthetreatmentofsleepdisordersassociatedwiththissyndrome.However,furtherresearchisnecessarytoconfirmtheseresultsandaddressthelimitationsofthisstudy.Withincreasededucationandawareness,itishoped