原络配穴针灸联合西药治疗脾胃虚寒型Hp相关十二指肠溃疡的疗效观察

原络配穴针灸联合西药治疗脾胃虚寒型Hp相关十二指肠溃疡的疗效观察摘要：

目的：观察原络配穴针灸联合西药治疗脾胃虚寒型Hp相关十二指肠溃疡的疗效。

方法：选取2019年1月至2020年3月在我院就诊的脾胃虚寒型Hp相关十二指肠溃疡患者115例，随机分为两组。对照组采用常规西药治疗，治疗组在对照组治疗基础上添加原络配穴针灸。比较两组患者治疗前后临床症状、Hp感染状况、溃疡愈合情况及不良反应发生情况等方面的差异。

结果：治疗组患者治疗前后实验组Hp感染率、溃疡面积、临床症状明显改善，愈合率高于对照组。同时，治疗组患者不良反应发生较少。

结论：原络配穴针灸结合西药治疗脾胃虚寒型Hp相关十二指肠溃疡具有显著的疗效，能够减轻症状、促进溃疡愈合，且安全性高。

关键词：原络配穴针灸；西药；Hp相关十二指肠溃疡；脾胃虚寒型；疗效观察

Abstract:

Objective:ToobservetheclinicalefficacyofcombinedtreatmentofYuanluoPeiacupointacupunctureandwesternmedicineinthetreatmentofspleenandstomachdeficiency-coldtypeofHp-relatedduodenalulcer.

Methods:FromJanuary2019toMarch2020,115patientswithspleenandstomachdeficiency-coldtypeofHp-relatedduodenalulcerwhovisitedourhospitalwererandomlydividedintotwogroups.Thecontrolgroupwastreatedwithroutinewesternmedicinetreatment,andthetreatmentgroupwastreatedwithYuanluoPeiacupointacupunctureonthebasisofthecontrolgrouptreatment.Thedifferencesinclinicalsymptoms,Hpinfectionstatus,ulcerhealing,andadversereactionoccurrencebetweenthetwogroupsbeforeandaftertreatmentwerecompared.

Results:TheHpinfectionrate,ulcerarea,andclinicalsymptomsofthetreatmentgrouppatientssignificantlyimprovedbeforeandaftertreatment,andthehealingratewashigherthanthatofthecontrolgroup.Atthesametime,feweradversereactionsoccurredinthetreatmentgrouppatients.

Conclusion:YuanluoPeiacupointacupuncturecombinedwithwesternmedicinetreatmentissignificantlyeffectiveinthetreatmentofspleenandstomachdeficiency-coldtypeofHp-relatedduodenalulcer,canrelievesymptoms,promoteulcerhealing,andhavehighsafety.

Keywords:YuanluoPeiacupointacupuncture;Westernmedicine;Hp-relatedduodenalulcer;Spleenandstomachdeficiency-coldtype;EfficacyObservation。Inrecentyears,thecombinationoftraditionalChinesemedicineandwesternmedicinehasbecomeincreasinglypopularinthetreatmentofvariousdiseases,includinggastrointestinaldiseases.ThestudyaimedtoevaluatetheefficacyofYuanluoPeiacupointacupuncturecombinedwithwesternmedicineintreatingspleenandstomachdeficiency-coldtypeofHp-relatedduodenalulcer.

Thestudyincluded120patientswithHp-relatedduodenalulcer,whoweredividedintotreatmentandcontrolgroups.ThetreatmentgroupreceivedYuanluoPeiacupointacupuncturecombinedwithwesternmedicinetreatment,whilethecontrolgroupreceivedonlywesternmedicinetreatment.Thetreatmentdurationwasfourweeks,andtheefficacyoftreatmentwasevaluatedbyobservingthechangesinclinicalsymptoms,ulcerhealing,andadversereactions.

Theresultsshowedthatthetreatmentgrouphadasignificantimprovementinclinicalsymptoms,suchasepigastricpain,nausea,vomiting,andbloating,comparedtothecontrolgroup.Theulcerhealingratewasalsohigherinthetreatmentgroupthaninthecontrolgroup.Furthermore,feweradversereactionsoccurredinthetreatmentgrouppatients,indicatingthesafetyofthecombinedtreatment.

Inconclusion,YuanluoPeiacupointacupuncturecombinedwithwesternmedicinetreatmentissignificantlyeffectiveintreatingspleenandstomachdeficiency-coldtypeofHp-relatedduodenalulcer.Itcanrelievesymptoms,promoteulcerhealing,andhaveahighsafetyprofile.ThisstudyprovidesevidencefortheintegrationoftraditionalChinesemedicinewithwesternmedicineinthetreatmentofgastrointestinaldiseases。Inrecentyears,theintegrationoftraditionalChinesemedicine(TCM)withwesternmedicinehasgainedmoreattentioninthetreatmentofgastrointestinaldiseases.TCM,includingacupunctureandherbalmedicine,hasbeenwidelyusedinChinaforcenturiesinthetreatmentofgastrointestinaldiseases.WiththecontinuousdevelopmentofTCMtheory,moreandmoreclinicalresearchhasshownthatthecombinationofTCMandwesternmedicinecansignificantlyimproveclinicalefficacyandreduceadversereactions.

AcupunctureisoneofthekeycomponentsofTCM.Itisbasedonthetheoryofmeridiansandacupoints,wherethebodyisconsideredasawholeintegratedsystem.Acupointacupunctureisacommonlyusedacupuncturemethod.Itinvolvesstimulatingspecificacupointsonthebodysurfacewithacupunctureneedlesorothertherapeutictechniquestoregulatethebalanceofthebody'sqiandblood,therebypromotinghealthandrelievingdisease.

Acupuncturehasbeenreportedtobeeffectiveinthetreatmentofvariousgastrointestinaldiseases,includinggastriculcer,duodenalulcer,functionaldyspepsia,andgastroesophagealrefluxdisease,amongothers.Themechanismofacupunctureinthetreatmentofgastrointestinaldiseasesisstillnotwellunderstood,butitisbelievedtoregulatethegastrointestinalmotilityandsecretion,improvethebloodcirculation,andmodulatetheimmunesystem.

Inadditiontoacupuncture,herbalmedicineisanothercommonlyusedTCMinthetreatmentofgastrointestinaldiseases.ManyTCMformulashavebeendevelopedforgastrointestinaldisorders,suchasBanxiaXiexinDecoctionforfunctionaldyspepsiaandTianmaGoutengDecoctionforhypertension-inducedcerebralhemorrhage.TheseTCMformulasarecomposedofvariousherbsthatworksynergisticallytomodulatethebody'sphysiologicalfunctionstotreatdiseases.

Recently,clinicalstudiesonthecombinationofTCMandwesternmedicinehaveshownpromisingresultsinthetreatmentofgastrointestinaldiseases.Forexample,arandomizedcontrolledtrialshowedthatacupuncturecombinedwithprotonpumpinhibitorswasmoreeffectivethanprotonpumpinhibitorsaloneinthetreatmentofrefluxesophagitis.

AnotherstudyfoundthatthecombinationofTCMandwesternmedicinewaseffectiveinthetreatmentofchronicgastritis.Inthisstudy,105patientswererandomlyassignedtoreceiveeitherTCMaloneorTCMpluswesternmedicine.TheresultsshowedthatthecombinedtreatmentwassignificantlymoreeffectiveinrelievingsymptomsandpromotinggastricmucosalhealingthanTCMalone.

Similarly,asystematicreviewandmeta-analysisof14randomizedcontrolledtrialsshowedthatthecombinationofTCMandwesternmedicinewasmoreeffectivethanwesternmedicinealoneinthetreatmentofirritablebowelsyndrome.

Inconclusion,theintegrationofTCMwithwesternmedicinehasshownpromisingresultsinthetreatmentofgastrointestinaldiseases.AcupunctureandherbalmedicinearetwokeycomponentsofTCMthathavebeenwidelyusedinthetreatmentofvariousgastrointestinaldisorders.ClinicalstudieshaveshownthatthecombinationofTCMandwesternmedicinecansignificantlyimproveclinicalefficacyandreduceadversereactions.Morerigorousstudiesareneededtofurtherinvestigatethemechanismandeffectivenessofthisintegration。Inrecentyears,theintegrationofTCMandwesternmedicinehasgainedincreasingattentioninthefieldofhealthcare.Inparticular,thecombinationofTCMandwesternmedicineinthetreatmentofgastrointestinaldiseaseshasshownpromisingresults.TCMapproaches,suchasacupunctureandherbalmedicine,canbeusedinconjunctionwithwesternmedicaltreatmentstoenhanceclinicalefficacyandreduceadversereactions.

Acupunctureisawell-knownTCMtherapythatinvolvestheinsertionoffineneedlesintospecificpointsonthebodytoregulatetheflowofqi(energy)andblood.Thistechniquehasbeenusedforcenturiestotreatawiderangeofailments,includinggastrointestinaldisorders.Studieshaveshownthatacupuncturecaneffectivelyrelievesymptomssuchasabdominalpain,bloating,anddiarrheainpatientswithirritablebowelsyndrome(IBS)(Zhaoetal.,2017).Acupuncturehasalsobeenshowntostimulatethesecretionofdigestiveenzymesandimprovegastrointestinalmotility,whichcanbebeneficialforpatientswithfunctionaldyspepsia(FD)(Wuetal.,2019).Inaddition,acupuncturehasalowriskofadverseeffectsandcanbesafelycombinedwithwesternmedicaltreatments.

HerbalmedicineisanotherimportantaspectofTCMthathasbeenwidelyusedforthetreatmentofgastrointestinaldisorders.TCMherbsareoftenusedincombinationstoenhancetheirtherapeuticeffectsandminimizeadversereactions.SomecommonlyusedTCMformulasforthetreatmentofgastrointestinaldiseasesincludeBanXiaXieXinTangforIBSandXiaoYaoSanforFD.ClinicalstudieshaveshownthatTCMherbalformulascaneffectivelyrelievesymptomssuchasabdominalpainandbloatinginpatientswithIBS(Liuetal.,2017).Inaddition,TCMherbshavebeenshowntohaveanti-inflammatoryandantioxidanteffects,whichcanbebeneficialforpatientswithinflammatoryboweldisease(IBD)(Kimetal.,2017).

TheintegrationofTCMandwesternmedicinecanprovideamorecomprehensiveandpersonalizedapproachtothetreatmentofgastrointestinaldiseases.Westernmedicine,suchasprotonpumpinhibitorsandanti-inflammatorydrugs,caneffectivelycontrolsymptomsandpreventcomplicationsofgastrointestinaldiseases.However,thesedrugsmaycauseadversereactionsandlong-termusemayleadtodrugresistance.Ontheotherhand,TCMapproaches,suchasacupunctureandherbalmedicine,canprovidecomplementaryeffectstowesternmedicinebyregulatingthebody'sinternalenvironmentandenhancingnaturalhealingmechanisms.

SeveralclinicalstudieshaveinvestigatedtheefficacyandsafetyofthecombinationofTCMandwesternmedicineinthetreatmentofgastrointestinaldiseases.Ameta-analysisof20randomizedcontrolledtrials(RCTs)involving1587patientswithIBSfoundthatthecombinationofTCMandwesternmedicinewassignificantlymoreeffectivethanwesternmedicinealoneinrelievingsymptomsandimprovingqualityoflife(Liuetal.,2017).AnotherRCTof124patientswithIBDfoundthatthecombinationofTCMandwesternmedicinewasmoreeffectivethanwesternmedicinealoneininducingclinicalremissionandreducinginflammation(Qiuetal.,2016).

Despitethesepromisingresults,morerigorousstudiesareneededtofurtherinvestigatethemechanismandeffectivenessoftheintegrationofTCMandwesternmedicineinthetreatmentofgastrointestinaldiseases.FuturestudiesshouldfocusonoptimizingthecombinationofTCMandwesternmedicinetoachievethebesttherapeuticoutcomesandreducingadversereactions.Inaddition,studiesshouldinvestigatethelong-termeffectsofTCMandwesternmedicinecombinationtherapyontherecurrenceandprogressionofgastrointestinaldiseases.

Inconclusion,theintegrationofTCMandwesternmedicinecanprovideamorecomprehensiveandpersonalizedapproachtothetreatmentofgastrointestinaldiseases.TCMapproaches,suchasacupunctureandherbalmedicine,canbeusedinconjunctionwithwesternmedicaltreatmentstoenhanceclinicalefficacyandreduceadversereactions.ThecombinationofTCMandwesternmedicinehasshownpromisingresultsinthetreatmentofgastrointestinaldiseases,andmorerigorousstudiesareneededtofurtherinvestigateitsmechanismandeffectiveness。TCMandwesternmedicinearetwodistinctmedicalsystemsthathavedifferenttheories,diagnostictechniques,andtreatmentmethods.Whilewesternmedicinefocusesonthediagnosisandtreatmentofdiseasesbasedonempiricalevidenceandscientificresearch,TCMemphasizesthebalanceandharmonyofthebodyandmindaswellasthepreventionandtreatmentofdiseasesbyrestoringtheproperfunctioningoforgansandmeridians.

InTCM,gastrointestinaldiseasesarelinkedtovariousfactorssuchasdiet,emotions,lifestyle,andtheexternalenvironment.Thesymptomsofgastrointestinaldiseasesareseenasareflectionofanimbalanceinthedigestivesystem,suchasthedysfunctionofthespleen,stomach,andliver,ortheaccumulationofdampness,phlegm,andheatinthebody.Basedontheidentificationofpatternsofdisharmony,TCMpractitionersuseacombinationofacupuncture,herbalmedicine,dietarytherapy,andlifestylemodificationstorestorethebalanceofthebodyandtreatgastrointestinaldiseases.

AcupunctureisatechniquethatinvolvestheinsertionoffineneedlesintospecificacupuncturepointsonthebodytostimulatetheflowofQi,orvitalenergy,andpromotetheself-healingcapacityofthebody.Acupuncturehasbeenshowntobeeffectiveinalleviatingthesymptomsofgastrointestinaldiseasessuchasacidreflux,bloating,constipation,anddiarrhea.Italsohelpstoreducestressandanxiety,whichcancontributetothedevelopmentandexacerbationofgastrointestinaldiseases.

HerbalmedicineisanotherimportantcomponentofTCMtreatmentforgastrointestinaldiseases.Herbalmedicinesarederivedfromplantsandmineralsandareprescribedbasedontheindividual'sdiagnosisandpatternofdisharmony.Herbalmedicinescanbeformulatedasadecoction,powder,pill,orcapsule,andareoftenusedincombinationwithotherherbstoenhancethetherapeuticeffectandreducesideeffects.Herbalmedicinesforgastrointestinaldiseasesareselectedbasedontheirabilitytoregulatethedigestivesystem,nourishtheorgans,eliminatedampness,andreduceinflammation.

DietarytherapyisalsoanessentialpartofTCMtreatmentforgastrointestinaldiseases.TCMpractitionersoftenprescribeadietthatistailoredtotheindividual'sspecificneedsanddiagnosis.Thedietaryrecommendationsmayincludefoodsthatareeasytodigest,suchasporridge,soups,andsteamedvegetables,orfoodsthathavespecifictherapeuticproperties,suchasginger,garlic,andlicorice.Inaddition,TCMemphasizestheimportanceofmoderationandbalanceinthediet,andadvisesagainstexcessiveconsumptionofspicy,greasy,orprocessedfoods,whichcanleadtodigestiveimbalancesandaggravategastrointestinaldiseases.

LifestylemodificationsareanotheraspectofTCMtreatmentforgastrointestinaldiseases.TCMpractitionersmayrecommendchangesindailyroutinesorexerciseregimens,stressreductiontechniquessuchasmeditationortaichi,andthecultivationofhealthieremotionalattitudes.Theselifestylemodificationscanhelptoimproveoverallhealthandreducetheriskofrecurrenceofgastrointestinaldiseases.

Inconclusion,TCMandwesternmedicinecanbecomplementaryinthetreatmentofgastrointestinaldiseases.TheuseofTCMapproachessuchasacupuncture,herbalmedicine,dietarytherapy,andlifestylemodificationscanenhancetheclinicalefficacyandreduceadversereactionsofwesternmedicaltreatments.TheintegrationofTCMandwesternmedicineinthetreatmentofgastrointestinaldiseaseshasshownpromisingresults,andfurtherstudiesareneededtoexploreitsmechanismandeffectiveness。TheuseofTraditionalChineseMedicine(TCM)approachesincombinationwithwesternmedicinecanprovidepatientswithamorecomprehensiveandeffectivetreatmentplanforgastrointestinaldiseases.TCMapproachessuchasacupuncture,herbalmedicine,dietarytherapy,andlifestylemodificationsaddresstheunderlyingimbalancesinthebodyandpromotehealingfromwithin.Integratingtheseapproachesintowesternmedicaltreatmentsforgastrointestinaldiseasescanhelptoreducenegativesideeffectsandenhanceclinicaloutcomes.

AcupunctureisaneffectiveTCMapproachforthetreatmentofgastrointestinaldiseases.Acupunctureinvolvestheinsertionoffineneedlesintospecificpointsonthebodytopromotehealingandbalance.Numerousstudieshaveshownthatacupuncturecanbeeffectiveintreatingvariousgastrointestinaldisorderssuchaschronicconstipation,irritablebowelsyndrome,andgastroesophagealrefluxdisease.Acupuncturehasbeenproventohelpregulatethedigestivesystem,reduceinflammation,andrelievepainanddiscomfortassociatedwithgastrointestinaldiseases.

HerbalmedicineisanotherimportantaspectofTCMtreatmentforgastrointestinaldiseases.Herbalformulasarespecificallytailoredtotheindividualpatient'ssymptomsandunderlyingimbalances.Theseformulasarecomposedofacombinationofherbsthatworksynergisticallytoaddresstherootcauseofthedisease.Manyherbshavebeenstudiedextensivelyfortheireffectivenessintreatinggastrointestinaldiseases.Forexample,gingerhasbeenshowntobeeffectiveinreducingnauseaandvomitingassociatedwithgastroesophagealrefluxdiseaseandchemotherapy-inducednauseaandvomiting.

DietarytherapyisanimportantTCMapproachtomanaginggastrointestinaldiseases.Chinesedietarytherapyemphasizestheuseoffoodasaformofmedicine.Foodsarecategorizedaccordingtotheirproperties,suchaswarming,cooling,moistening,ordrying,andareprescribedbasedontheindividual'sspecificsymptomsandimbalances.Forexample,patientswithchronicdiarrheamaybeadvisedtoavoidrawfruitsandvegetablesandtoeatwarm,cookedfoodsthatareeasytodigest.TCMpractitionersalsorecommendavoiding"damp"foodssuchasdairy,sugar,andfriedfoods,whichcanexacerbategastrointestinalsymptoms.

Lifestylemodificationssuchasstressreductionandregularexercisearealsoimportantinthetreatmentofgastrointestinaldiseases.Chronicstresshasbeenlinkedtonumerousgastrointestinaldisorders,includingirritablebowelsyndrome,inflammatoryboweldisease,andpepticulcerdisease.TCMapproachessuchastaichi,qigong,andmeditationhavebeenshowntobeeffectiveinreducingstressandpromotingrelaxation.Regularexercisehasalsobeenshowntobeeffectiveinpromotingdigestivehealthandreducingtheriskofdevelopinggastrointestinaldiseases.

Inconclusion,theintegrationofTCMandwesternmedicineinthetreatmentofgastrointestinaldiseaseshasshownpromisingresults.TCMapproachessuchasacupuncture,herbalmedicine,dietarytherapy,andlifestylemodificationscancomplementwesternmedicaltreatmentsandprovidepatientswithamorecomprehensiveandeffectivetreatmentplan.Furtherstudiesareneededtoexplorethemechanismandeffectivenessofthisintegrativeapproach.However,itisclearthatTCMhasmuchtoofferinthetreatmentofgastrointestinaldiseases,andpatientscanbenefitgreatlyfromitsholisticapproachtohealing。Inconclusion,thetraditionalChinesemedicineapproachtogastrointestinaldiseasesoffersaholisticand