靶向分子适配文献总结报告课件

1、Aptamer 应用文献总结靶向药物传递 Aptamer-functionalized PEGPLGA nanoparticles for enhanced antiglioma drug delivery (2011,Biomaterials)AS1411 DNA aptamer 5-TTGGTGGTGGTGGTTGTGGTGGTGGTGG-3胶质瘤细胞（C6 glioma cell ）1、 PEGylated Anti-MUC1 Aptamer-Doxorubicin Complex or Targeted Drug Delivery to MCF7 Breast Cancer Cells

2、（2011，Macrolecular Bioscience）MUC1 DNA aptamer乳腺癌细胞（MCF7）2、 Tumor targeted quantum dot-mucin 1 aptamer-doxorubicin conjugate for imaging and treatment of cancer（2011, Journal of Controlled Release）MUC1 DNA aptamer 5-GCA-GTT-GATCCT-TTG-GAT-ACC-CTG-G-3卵巢癌细胞（ovarian ） 3、 Novel Aptamer-Nanoparticle Bioc

3、onjugates Enhances Delivery of Anticancer Drug to MUC1-Positive Cancer Cells In Vitro（2011，PolS ONE） A modified aptamer S2.2-spacer : 5-GCA GTT GAT CCT TTG GAT ACC CTG GTT CCC TTC CTT CTC TCT TCC TCT CTC CTT CTC TCT TCC TCT CTC CTT C-3 乳腺癌细胞（MCF-7） 4、 Aptamer-Conjugated DNAIcosahedral Nanoparticles

4、As a Carrier of Doxorubicin for Cancer Therapy（2011，ACS NANO）MUC1 aptamerMCF-75、 A liposome-based nanostructure for aptamer directed delivery（2010, Chem. Commun） Sgc8 T淋巴细胞急性白血病细胞（CEM)7、8、 Nanoparticle-Aptamer Bioconjugates: A New Approach for Targeting Prostate Cancer Cells （2010, Chem. Commun） A10

5、 PMSM 前列腺癌细胞（PC3） Quantum Dot-Aptamer Conjugates forSynchronous Cancer Imaging, Therapy, and Sensing of Drug Delivery Based on Bi-Fluorescence Resonance Energy Transfer（2007，NANO LETTERS）A10 PMSM前列腺癌细胞（LNCaP cell）9、10、 Aptamer Biosensor Based on Fluorescence Resonance Energy Transfer from Upconverti

6、ng Phosphors to Carbon Nanoparticles for Thrombin Detection in Human Plasma（2011,Analytical Chemistry） thrombin aptamer (5-NH2- GGTTGGTGTGGTTGG-3) 凝血酶量子点、上转换荧光检测靶向光热治疗、光动力治疗 Gold Nano-Popcorn Attached SWCNT Hybrid Nanomaterial for Targeted Diagnosis and Photothermal Therapy of Human Breast Cancer Ce

7、lls（2011，ACS APPLIED MATERIALS &INTERFACES） S6 aptamer乳腺癌细胞（SK-BR-3） 12、 Regulation of Singlet Oxygen Generation Using Single-Walled Carbon Nanotubes（2008，JACS） B细胞淋巴瘤细胞Romas cell 13、14、 Aptamer-Based Tumor-Targeted Drug Delivery for Photodynamic Therapy（ACS NANO） AS1411 : 5GGTGGTGGTGGTTGTGG TGGTGG

8、TGG-3MCF-7 靶向基因治疗 Molecular imaging of a cancer-targeting theragnostics probe using a nucleolin aptamer- and microRNA-221 molecular beacon-conjugated nanoparticle（2012，Biomaterials） AS1411 5-GGTGGTGGTGGTTGTGGTGGTGG TGG3 胶质瘤细胞（C6 cell）15、Stimuli-responsive releasing of goldnanoparticles and liposomes from aptamerfunctionalized hydrogel（2011，Nanotechnology） 腺苷17、 A hybrid particlehydrogel composite for oligonucleotide-mediated pulsatile protein release（2010，Soft Matter） anti