EN460-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEEN460Cat. No.: HY-12837CAS No.: 496807-64-8分式: CHClFNO分量: 460.79作靶点: Others作通路: Others储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 16.67 mg/mL (36.18 mM; Need ultrasonic)Mass Solvent1 mg

2、 5 mg 10 mg Concentration制备储备液1 mM 2.1702 mL 10.8509 mL 21.7019 mL5 mM 0.4340 mL 2.1702 mL 4.3404 mL10 mM 0.2170 mL 1.0851 mL 2.1702 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的

3、体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 1.67 mg/mL (3.62 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 1.67 mg/mL (3.62 mM); Clear solutionBIOLOGICAL ACTIVITY1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE物活性 EN460ERO1分抑制剂，IC50值1.9uM。户使本产品发表的科研献

4、 J Exp Clin Cancer Res. 2019 Jan 31;38(1):44.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Blais JD, et al. A small molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1) with selectively reversible thiol reactivity. J BiolChem. 2010 Jul 2;285(27):20993-1003.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: