Tianeptine-sodium-salt - 5-HT Receptor Agonist - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemETianeptine sodium saltCat. No.: HY-90003ACAS No.: 30123-17-2分式: CHClNNaOS分量: 458.93作靶点: 5-HT Receptor作通路: GPCR/G Protein; Neuronal Signaling储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 H2O : 23

2、5 mg/mL (512.06 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.1790 mL 10.8949 mL 21.7898 mL5 mM 0.4358 mL 2.1790 mL 4.3580 mL10 mM 0.2179 mL 1.0895 mL 2.1790 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Tianeptine钠盐是5-HT吸收促进剂。

3、户使本产品发表的科研献 Nat Commun. 2018 Oct 15;9(1):4272.1/2 Master of Small Molecules 您边的抑制剂师www.MedChemESee more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Broqua P; Baudrie V; Chaouloff F Differential effects of the novel antidepressant tianeptine on L-5-hydroxytryptophan (5-HTP)-elicitedc

4、orticosterone release and body weight loss. Eur Neuropsychopharmacol. 1992 Jun;2(2):115-20.2. Orescanin-Dusic Z, et al. Tianeptines effects on spontaneous and Ca2+-induced uterine smooth muscle contraction. Acta Physiol Hung.2012 Jun;99(2):140-7.3. Della FP, Abelaira HM, Rus GZ, Ribeiro KF, Antunes

5、AR, Scaini G, Jeremias IC, Dos Santos LM, Jeremias GC, Streck EL, QuevedoJ.Tianeptine treatment induces antidepressive-like effects and alters BDNF and energy metabolism in the brain of rats.Behav Brain Res.2012 Aug 1;233(2):526-35. Epub 2012 May 31.4. Sohn W, Lee OY, Kwon JG, Park KS, Lim YJ, Kim T

6、H, Jung SW, Kim JI.Tianeptine vs amitriptyline for the treatment of irritable bowelsyndrome with diarrhea: a multicenter, open-label, non-inferiority, randomized controlled study.Neurogastroenterol Motil. 2012Sep;24(9):860-e398.5. Orola L, Veidis MV, Sarcevica I, Actins A, Belyakov S, Platonenko A.The effect of pH on polymorph formation of the pharmaceuticallyactive compound tianeptine.Int J Pharm. 2012 Aug 1;432(1-2):50-6. Epub 2012 Apr 30.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.