Dienogest-STS-557-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEDienogestCat. No.: HY-B0084CAS No.: 65928-58-7Synonyms: STS 557分式: CHNO分量: 311.42作靶点: Progesterone Receptor; Autophagy作通路: Others; Autophagy储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 2

2、5 mg/mL (80.28 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 3.2111 mL 16.0555 mL 32.1110 mL5 mM 0.6422 mL 3.2111 mL 6.4222 mL10 mM 0.3211 mL 1.6055 mL 3.2111 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建

3、议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (8.03 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (8.03 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oil1/2 Maste

4、r of Small Molecules 您边的抑制剂师www.MedChemESolubility: 2.5 mg/mL (8.03 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Dienogest(STS-557)孕酮受体激动剂，有服的宫内膜活性，可作于宫内膜异位。REFERENCES1. Oettel M, et al. Effect of ethinyl estradiol-dienogest combination on serum androgen concentrations. Zentralbl Gynakol.1997;119(12):5

5、97-606.2. Meena R, et al. Extended intervention time and evaluation of sperm suppression by dienogest plus testosterone undecanoate in malerat. Contraception. 2012 Jan;85(1):113-21.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-58955