纪立农从高血糖与糖尿病周围神经病变的关系反思和控制策略

从高血糖与糖尿病周围神经病变的关系反思研究和控制策略北京大学人民医院

纪立农ChinaCardiometabolicRegistries2Nation-wide,prospective,registryseriesdesignedtobetterunderstandclinicaloutcomesof

currenttreatmentofcardiovascularandmetabolicdiseasesinrealworldsettingsOrganizedbyChineseMedicalDoctorAssociationsSupervisedbyCCMRInternationalAdvisoryBoardManagedbyVitalStrategicResearchInstitute

ChinaCardiometabolicRegistries

研究者会议

2011年5月14-15日中国2型糖尿病患者心血管疾病危险因素的纵向队列研究

中国老年学学会（GSC）主办

中国医师协会心血管内科医师分会(CCCP)协办中国医师协会内分泌及代谢科医师分会(CEA)协办中国心血管代谢病系列研究(CCMR)组织及专家委员会

指导华斯泰生命策略研究所/上海华斯泰医学咨询有限公司(VSRI)执行默沙东(中国)有限公司赞助NationwideAssessmentofCardiovascularRiskFactors--BloodPressure,BloodLipid,andBloodGlucoseinChinesePatientswithType2DiabetesLinongJi

PekingUniversityPeople’sHospital

OnbehalfofCCMRAdvisoryBoardJietal.AJM，2013，inpressStudyObjectives–PrimaryPrimaryObjectiveToassessthelevelofcontrolofCVDriskfactors,includingbloodpressure,bloodlipid,andbloodglucose,inoutpatientswithtype2DMin6representativeregionsinChinaandinthreetiersofhospitalsToidentifythegapbetweenrealworlddiabetesmanagementsituationandstandardofcare4Jietal.AJM，2013，inpressStudyObjectives-SecondarySecondaryObjectivesToassesstheproportionofmicrovascularandmacrovasclardiabeticcomplicationsinoutpatientswithtype2DMToassessreal-lifetreatmentpatternsinoutpatientswithtype2DMToassesstheproportionofhypoglyecemiaunderthecurrenttreatmentToassesstheinfluencingfactors(hospitalclassification,regionaldistribution,medicalhistory,educationallevelandothers)onDMtreatmentoutcomes5Jietal.AJM，2013，inpressNon-interventional,observational,cross-sectionaldesignType2diabetesdiagnosedfor6monthsorlongerAmbulatorypatientsfromendocrinology,cardiology,nephrologyclinicsinall3tiersofhospitals(Tier1,2,and3)locatedinall6mainregionsinChinaEstimatedsamplesizewas25,000patientsinordertohavesufficientpowertodetectthedifferenceoftheprimaryassessmentineachregion666StudyDesignTargetedtoenroll25,000patientsJietal.AJM，2013，inpressDistributionofParticipatingHospitals7NumberofsitesineachregionwasproportionaltothepopulationintheregionNationalRegionsTier1Tier2Tier3SUMNorthEast46616North46818East57618NorthWest45514SouthWest59721CentralSouth45716SUM263839103Jietal.AJM，2013，inpressCharacteristicsofstudysubjects8NumberPercentage(%)All25454100.0Age(yr)<651385554.5

>651159945.5GenderMale1195547.0Female1349953.0ResidentUrban2277689.5Rural267810.5BMI(kg/m2)<241061741.7

>241483558.3Meanage=62.6+/-11.9yearsJietal.AJM，2013，inpressDistributionofCVDRiskFactors28%ofthepatientshadT2Donly60%ofthepatientsalsohadHTN(T2D+HTN)About42%ofthepatientsalsohadDYLP(T2D+DYLP)About30%ofthepatientshad“3B”:highbloodglucose,bloodlipid,

andbloodpressure(T2D+HTN+DYLP)9T2D=type2diabetes,HTN=hypertension,DYLP=dyslipidemiaJietal.AJM，2013，inpressDi糠ab左et艳es揪D源ur钥at塔io痕n找an脚d纤Co敢mp四li怒ca钻ti胜on躲s10Pr纺ev誉al授en正ce盛o斜f攀di柔ab脆et利ic采c杰om拘pl球ic撒at乎io鬼ns俱i拌s滋pr庙op搜or漫ti差on呈al炕t纺o吉du制ra毛ti她on茶o螺f引di借ab涨et皮es(%创)Du前ra缓ti冤on趁o泼f吼Di嫁ab喷et糠esJi汽e赢t藏al监.尤A冶JM，20匹13，in躬p锁re与ssDi愁ab和et本ic悠C错om挡pl日ic稻at水io废ns意a蜡nd喊C钞VD寒Ri均sk翼F座ac酿to茫rs11(%地)Ji确e唐t心al他.军A禁JM，20卵13，in酷p姜re春ssCa翅ll凉ag源ha计nBC，et添a政l.Co满ch看ra冻neDa经ta外ba伤se杠S颜ys妇t位Re盟v.20甲12Ca雕ll慕ag训ha料nBC，et玻a忽l.Co钞ch括ra料neDa降ta幅ba诸se糠S盐ys士t领Re绸v.20久12Ca锦ll样ag扣ha逢nBC，et蹈a纸l.Co贸ch翼ra狠neDa涂ta羡ba家se罗S托ys胞t裙Re喂v.20呀12Ca他ll由ag落ha伍nBC，et啦a蹄l.Co本ch咏ra馆neDa闻ta射ba弃se司S墓ys碰t翅Re什v.20更12Ca挺ll驻ag别ha叫nBC，et套a输l.Co盲ch铺ra重neDa辜ta斤ba用se鬼S落ys瞧t离Re举v.20体12Ca搂ll秤ag嘱ha屋nBC，et搬a德l.Co阴ch赛ra个neDa螺ta区ba雪se跳S队ys晨t种Re催v.20叔12Ca年ll迹ag板ha童nBC，et拍a欠l.Co凳ch货ra历neDa伙ta酷ba的se独S虏ys侨t臂Re卖v.20棒12Ca鼓ll赤ag坐ha郑nBC，et扑a拖l.Co蛛ch瞒ra跌neDa捧ta缩慧ba坚se忌S辅ys镇t睁Re讽v.20蛙12Ca抛ll醉ag看ha考nBC，et浊a殿l.Co鸟ch培ra劝neDa嫁ta土ba亚se汤S在ys展t状Re唱v.20慕12Ca仓ll朽ag延ha洁nBC，et鲜a东l.Co餐ch嫌ra租neDa教ta攀ba加se圆S描ys皂t足Re糖v.20兼12Ca局ll影ag名ha歉nBC，et逆a脊l.Co沃ch跑ra转neDa绵ta支ba伶se蜻S乖ys崖t舍Re虽v.20多12Ca饱ll煎ag守ha追nBC，et语a目l.Co贩ch院ra摔neDa迈ta惰ba键se境S爱ys傲t份Re距v.20到12Gæ搞de吧,含P.眼e异t.逐a匠l.掀N发E跃ng独l欠JMe扮d勒20各03勾;3毅48壳:3撑83泡-3猴93Re计su虾lt朋s梳fr生om堆P差at煎ie叉nt杰s嚷wi喊th针T提yp挣e2Di盆ab情et千es泉-ST创EN躲O2Di金ab虫et止ic累N泽eu仿ro茶pa侨th办y腿in尿T露yp吵e煎2落Pa降ti性en闲tsPa行ti量en基tsca扛n阴be刮c眼la粗ss朱if政ie药d评in峡to2gr撒ou康psba裳se船d阿onmy爆el校in惹at绢ed叹f圈ib逮er访d最en勺si系tylo洪ssov赔er岸5踩2防we攻ek所sMF倡DSu砌ra锦lne碧rv筒ebi靠op愉si占es配o派f顿42淡7pa迎ti秋en比tsTRIGLYCERIDESWi叔gg狼in贤e密t生al蜓,挨Di图a