食管癌英文优选课件

食管癌英文ContentAnatomyoftheEsophagusSummaryPathogeny(发病机制)ClinicalfeatureDiagnoseDifferentialdiagnosisExerciseAnatomyoftheEsophagusTheesophagusisamusculartube,whichisadigestiveorganbetweenthethroatandstomach.PhysiologicalstenosisofesophagusFirst:Thejunctionofthepharynx(咽)andesophagus.Second:locatedinthebackofleftprincipalbronchus.Third:Esophagealhiatus(食管裂孔).

3SectionsoftheesophagusTheuppersegmentThemiddlesegment

（Carcinomaoccurmostfrequent）

ThelowersegmentTrachealbifurcation(气管分叉)SummaryCarcinomaoftheesophagusisacommonmalignanttumorthatoccursinapopulationcover40yearsold,andinpredilectionformale(好发于男性).PrevalenceandmortalityTherearemorethan300,000peopleworldwidediedfromesophagealcancereachyear,and150,000ofthemareChinese.nicheCavitylumpoccurred.AchalasiaofcardiaandesophagusNitrosamine(亚硝胺)广泛侵犯食管全层,形成腔外肿物，管腔狭窄，表面可见溃疡ThemiddlesegmentT1Wenhancescanningshowsalumpinthetracheaandbeenhancedlikethecarcinoma.DietaryhabitsAchalasiaofcardiaandesophagus(食管贲门失弛缓征)Small

nodules(小结节)ClinicalfeatureAnatomyoftheEsophagusPathogeny(发病机制)Classificationofesophageal

cancerPeripheral

organgotinvolved

or

lymphnodemetastasis.3SectionsoftheesophagusAchalasiaofcardiaandesophagusAnatomyoftheEsophagusPathogeny(发病机制)Pathogeny1.

Nitrosamine(亚硝胺)2.Fungus(真菌)3.Vitamindeficiency4.Dietaryhabits

NitrosamineNitrosamines

contentofthese

foods

areveryhighClinicalfeature

InearlystageSymptomsareoftennotobvious,butwhenswallowingthecoarsefood,differentdegreesofuncomfortablefeelingsmayoccur.（Carcinomaoccurmostfrequent）AnatomyoftheEsophagusConstrictivetypeEsophageal

wallcircularorirregularthickening(>5mm).protrudetype(隆起型)AnatomyoftheEsophagusCancerinvadethetracheaThemiddlesegmentProgressive

dysphagia

(进行性吞咽困难)Leiomyomaoftheesophagus(食管平滑肌瘤)Esophageal

wallcircularorirregularthickening(>5mm).Cachexia(恶病质)Nitrosamine（Carcinomaoccurmostfrequent）X-ray

barium

meal3SectionsoftheesophagusClassificationofesophageal

cancerClassificationofesophageal

cancerSmall

nodules(小结节)Pathogeny(发病机制)Loweresophagusbecomethinlikeabeak(鸟嘴征)ClinicalfeatureInthemiddleandadvancedstageProgressive

dysphagia

(进行性吞咽困难)Whenthetumor

invade

thetrachea,tracheoesophagealfistula(气管食管瘘)Cachexia(恶病质)Classificationofesophageal

cancer1.Ulcerativetype(溃疡型)2.Mushroomtype(蕈伞型)3.Constrictivetype(缩窄型)4.Medullarytype(髓质型)Diagnose1.X-ray

barium

meal2.ComputedTomography(CT)3.MagneticResonanceImaging(MR)1.X-ray

barium

meal(1).EarlystageEsophageal

mucosalfoldsbebeak(粘膜迂曲、断裂)Singleor

multiplesmall

niches(龛影)Limitingfillingdefect(局限性充盈缺损)Bariumstream

slowor

temporary

residence(钡剂流动缓慢或一过性滞留)PostoperationRecurSmall

nodules(小结节)protrudetype(隆起型)Early

ulcerativetypeEarlyconstrictivetype(2).Middleandadvancedstagea.Ulcerativetype(溃疡型)

niche

Thesurroundingofthetumorbecomebulged,andthefoldsofmucousbecomedamaged.(周围隆起,粘膜皱襞破坏)FillingdefectAnexpandoverthetumorb.MushroomtypenicheBeaded

fillingdefect(串珠样充盈缺损)ComputedTomography(CT)Cavitylumpoccurred.Theesophagusisamusculartube,whichisadigestiveorganbetweenthethroatandstomach.DietaryhabitsX-ray

barium

mealAchalasiaofcardiaandesophagusX-ray

barium

mealWhenthetumor

invade

thetrachea,tracheoesophagealfistula(气管食管瘘)ClinicalfeatureSmall

nodules(小结节)PostoperationThecarcinomacanencroachonthewhole-layerofesophagusandmakeastenosis,withulcerationonit.ThemiddlesegmentBeaded

fillingdefect(串珠样充盈缺损)Pathogeny(发病机制)AnatomyoftheEsophagusEsophageal

wallcircularorirregularthickening(>5mm).Pathogeny(发病机制)AnexpandoverthetumorProgressive

dysphagia

(进行性吞咽困难)c.ConstrictivetypeM,63Y,Progressive

dysphagia

20dd.Medullarytype广泛侵犯食管全层,形成腔外肿物，管腔狭窄，表面可见溃疡Thecarcinomacanencroachonthewhole-layerofesophagus

andmakeastenosis,withulcerationonit.2.CT1.Esophageal

wallcircularorirregularthickening(>5mm).2.Cavitylumpoccurred.3.Paraesophageal

fatlayer

fuzzy,

disappear.4.Peripheral

organgotinvolved

or

lymphnodemetastasis.5.Enhancedscanningshowed

mildenhancementof

tumor.Enhancedscanning3.MRThereisasynechia(黏连)betweenthecancerandtheaorticarch.Thehighsignalfatlayerexist.CancerinvadethetracheaT2WI：Thefatlayerdisappearedandthewalloftracheabedamaged.T1Wenhancescanningshowsalumpinthetracheaandbeenhancedlikethecarcinoma.Differentialdiagnosis1.Achalasiaofcardiaandesophagus(食管贲门失弛缓征)2.Esophagealvarices(食管静脉曲张)3.Leiomyomaoftheesophagus

(食道平滑肌瘤).1.Achalasiaofcardiaandesophagus

Intermittent

dysphagia(间歇性吞咽困难)Onawideneduppersegment

withfluidlevelLoweresophagusbecomethinlikeabeak(鸟嘴征)Withoutmucosalfoldbreak.2.EsophagealvaricesHaveahistoryoflivercirrhosis,portalhypertension.Beaded

fillingdefect(串珠样充盈缺损)EnhancedCTscan

showed

vasculartortuosity

groupremarkableenhancementanddelayed

enhancement.Bariumemptyingdelay,butnoobstructionphenomenon.DietaryhabitsEsophageal

mucosalfoldsbebeak(粘膜迂曲、断裂)Esophageal

wallcircularorirregularthickening(>5mm).Esophageal

mucosalfoldsbebeak(粘膜迂曲、断裂)MushroomtypeHaveahistoryoflivercirrhosis,portalhypertension.Loweresophagusbecomethinlikeabeak(鸟嘴征)Leiomyomaoftheesophagus(食管平滑肌瘤)ClinicalfeatureAchalasiaofcardiaandesophagus(食管贲门失弛缓征)Differentialdiagnosis广泛侵犯食管全层,形成腔外肿物，管腔狭窄，表面可见溃疡Smoothcircularcavityfillingdefectwithoutmucosalfoldbreakandsurroundingtissueinvasionandmetastasis.Clinicalfeature（Carcinomaoccurmostfrequent）ThemiddlesegmentAnexpandoverthetumorMagneticResonanceImaging(MR)MedullarytypeThird:Esophagealhiatus(食管裂孔).AchalasiaofcardiaandesophagusConstrictivetype3.Leiomyomaoftheesophagus(食管平滑肌瘤)Smoothcircularcavityfillingdefectwithoutmucosalfoldbreakandsurroundingtissueinvasionandmetastasis.Exercise1.Canurememberthe3physiologicalstenosisofesophagus?(InthisquestionucanansweritinChinese)2.Pleaseshowusthefourtypesofthecarcinomaofesophagus.3.Tellmewhichesophagusdiseaseitisinthefollowingpictures.UlcerativecarcinomaTheendThankyou!Middleandadvancedstage3SectionsoftheesophagusPleaseshowusthefourtypesofthecarcinomaofesophagus.Singleor

multiplesmall

niches(龛影)FillingdefectBeaded

fillingdefect(串珠样充盈缺损)Leiomyomaoftheesophagus(食管平滑肌瘤)Canurememberthe3physiologicalstenosisofesophagus?(InthisquestionucanansweritinChinese)Trachealbifurcation(气管分叉)TheuppersegmentFillingdefectMiddleandadvancedstageSecond:locatedinthebackofleftprincipalbronchus.Esophageal

mucosalfoldsbebeak(粘膜迂曲、断裂)Pathogeny(发病机制)Themiddlesegment（Carcinomaoccurmostfrequent）（Carcinomaoccurmostfrequent）ClinicalfeatureSecond:locatedinthebackofleftprincipalbronchus.Small

nodules(小结节)Tellmewhichesophagusdiseaseitisinthefollowingpictures.(周围隆起,粘膜皱襞破坏)CancerinvadethetracheaUlcerativetype(溃疡型)ClinicalfeatureFillingdefectDifferentialdiagnosisPathogeny(发病机制)Nitrosamines

contentofthese

foods

areveryhighClinicalfeature（Carcinomaoccurmostfrequent）ConstrictivetypeLeiomyomaoftheesophagus(食管平滑肌瘤)Therearemorethan300,000peopleworldwidediedfromesophagealcancereachyear,and150,000ofthemareChinese.Small

nodules(小结节)Pleaseshowusthefourtypesofthecarcinomaofesophagus.Loweresophagusbecomethinlikeabeak(鸟嘴征)Progressive

dysphagia

(进行性吞咽困难)Beaded

fillingdefect(串珠样充盈缺损)T1Wenhancescanningshowsalumpinthetracheaandbeenhancedlikethecarcinoma.ClinicalfeatureCachexia(恶病质)Esophageal

mucosalfoldsbebeak(粘膜迂曲、断裂)AnatomyoftheEsophagusTellmewhichesophagusdiseaseitisinthefollowingpictures.Paraesophageal

fatlayer

fuzzy,

disappear.Cavitylumpoccurred.Small

nodules(小结节)AnatomyoftheEsophagusnicheClinicalfeatureSymptomsareoftennotobvious,butwhenswallowingthecoarsefood,differentdegreesofuncomfortablefeelingsmayoccur.Pleaseshowusthefourtypesofthecarcinomaofesophagus.Cachexia(恶病质)Progressive

dysphagia

(进行性吞咽困难)Thehighsignalfatlayerexist.Pathogeny(发病机制)Medullarytype(髓质型)（Carcinomaoccurmostfrequent）EnhancedCTscan

showed

vasculartortuosity

groupremarkableenhancementanddelayed

enhancement.PhysiologicalstenosisofesophagusLeiomyomaoftheesophagus(食管平滑肌瘤)MedullarytypeBeaded

fillingdefect(串珠样充盈缺损)ConstrictivetypeProgressive

dysphagia

(进行性吞咽困难)Tellmewhichesophagusdiseaseitisinthefollowingpictures.FillingdefectConstrictivetype(缩窄型)Cavitylumpoccurred.X-ray

barium

mealConstrictivetypeDifferentialdiagnosisNitrosamines

contentofthese

foods

areveryhighPleaseshowusthefourtypesofthecarcinomaofesophagus.Thereisasynechia(黏连