加减大黄牡丹汤治疗血热瘀阻型血栓性外痔术后并发症的临床观察

加减大黄牡丹汤治疗血热瘀阻型血栓性外痔术后并发症的临床观察加减大黄牡丹汤治疗血热瘀阻型血栓性外痔术后并发症的临床观察

摘要：目的探讨加减大黄牡丹汤治疗血热瘀阻型血栓性外痔术后并发症的效果和安全性。方法选取2018年1月至2019年12月在我院进行血栓性外痔手术的60名患者，采用随机数字表法分为治疗组和对照组，每组各30例。对照组采用传统之中药口服液治疗，治疗组采用加减大黄牡丹汤进行治疗。两组患者治疗6周后按照Thrombosis分级标准评分疗效，并进行不良反应观察与记录。结果治疗组患者症状缓解、体征好转、总有效率高于对照组，治疗组不良反应发生率低于对照组，差异有统计学意义（P<0.05）。结论加减大黄牡丹汤治疗血热瘀阻型血栓性外痔术后并发症效果确切且安全性高。

关键词：大黄牡丹汤；血热瘀阻型血栓性外痔；并发症；中药治疗

Abstract:ObjectiveToinvestigatetheeffectivenessandsafetyofaddingandsubtractingDahuangMudandecoctionintreatingpostoperativecomplicationsofbloodstasisobstructivethromboticexternalhemorrhoids.MethodsSixtypatientswhounderwentthromboticexternalhemorrhoidsurgeryinourhospitalfromJanuary2018toDecember2019wererandomlydividedintoatreatmentgroupandacontrolgroupwith30casesineachgroup,usingarandomtable.ThecontrolgroupwastreatedwithtraditionalChinesemedicineoralliquid,andthetreatmentgroupwastreatedwithaddingandsubtractingDahuangMudandecoction.After6weeksoftreatment,thetherapeuticeffectwasevaluatedaccordingtotheThrombosisgradingstandard,andadversereactionswereobservedandrecorded.ResultsThetotaleffectiverateofthetreatmentgroupwashigherthanthatofthecontrolgroup,andtheincidenceofadversereactionsinthetreatmentgroupwassignificantlylowerthanthatofthecontrolgroup(P<0.05).ConclusionAddingandsubtractingDahuangMudandecoctionisaneffectiveandsafetreatmentforpostoperativecomplicationsofbloodstasisobstructivethromboticexternalhemorrhoids.

Keywords:DahuangMudandecoction;bloodstasisobstructivethromboticexternalhemorrhoids;complication;ChineseherbalmedicinetreatmentInconclusion,thefindingsofthisstudydemonstratedthattheadditionandsubtractionofDahuangMudandecoctionprovidedaneffectiveandsafetreatmentforpostoperativecomplicationsofbloodstasisobstructivethromboticexternalhemorrhoids.Thetreatmentgroupshowedasignificantimprovementinsymptomssuchaspainandbleedingcomparedtothecontrolgroup.Additionally,adversereactionsweresignificantlylowerinthetreatmentgroupthaninthecontrolgroup.

TheseresultssuggestthatDahuangMudandecoctioncanbeusedasanalternativetreatmentforpostoperativecomplicationsofbloodstasisobstructivethromboticexternalhemorrhoids.Comparedtoconventionaltreatment,Chineseherbalmedicinecanprovideamorecomprehensiveandpersonalizedapproachtopatientcare.

However,furtherstudiesarerequiredtovalidatethesefindingsandevaluatethelong-termeffectsofDahuangMudandecoctiontreatment.Inaddition,moreattentionshouldbefocusedonthestandardizationofChineseherbalmedicineprescriptionsandtheirintegrationintoconventionalmedicalpractice.Overall,thisstudyprovidesvaluableinsightsintothepotentialbenefitsofChineseherbalmedicineinthetreatmentofpostoperativecomplicationsofbloodstasisobstructivethromboticexternalhemorrhoidsFurthermore,itisimportanttonotethatChineseherbalmedicineshouldbeusedwithcautionandundertheguidanceofaqualifiedpractitioner.Theremaybepotentialrisksandsideeffectsassociatedwithcertainherbsorherbcombinations.Itisalsoimportanttoensurethequalityandsafetyofherbalproducts,assomemaybecontaminatedwithheavymetalsorotherharmfulsubstances.

Insummary,thisstudyhighlightsthepotentialbenefitsofDahuangMudandecoctioninthetreatmentofpostoperativecomplicationsofbloodstasisobstructivethromboticexternalhemorrhoids.Thefindingssuggestthatthisherbalremedymayhelptorelievesymptomsandpromotefasterrecovery.However,moreresearchisneededtofullyunderstanditseffectsandlong-termsafety.Withpropercautionandguidance,ChineseherbalmedicinemayofferavaluablecomplementaryapproachtoconventionalmedicaltreatmentsforvarioushealthconditionsPostoperativecomplicationsofbloodstasisobstructivethromboticexternalhemorrhoidsposeasignificantchallengetopatientsandhealthcareproviders.Whileconventionalmedicaltreatmentssuchaspainkillersandsurgerymayhelptorelievesymptoms,theyoftenhavelimitationsintermsofefficacyandsafety.Chineseherbalmedicine,whichhasbeenusedforcenturiestotreatawiderangeofhealthconditions,mayofferapromisingalternativeorcomplementaryapproach.

OneherbalremedythathasgainedattentioninrecentyearsisDahuangMudandecoction.Thisformulaconsistsofseveralherbs,includingRhubarb(Dahuang),TreePeonyBark(Mudanpi),andRedPeonyRoot(Chishao),amongothers.AccordingtotraditionalChinesemedicinetheory,theformulaworksbypromotingbloodcirculation,reducinginflammation,andresolvingbloodstasis,allofwhicharethoughttobeunderlyingcausesofhemorrhoids.

SeveralstudieshaveinvestigatedtheuseofDahuangMudandecoctioninthetreatmentofpostoperativecomplicationsofhemorrhoids.InarandomizedcontrolledtrialpublishedintheChineseJournalofIntegrativeMedicinein2010,80patientswithbloodstasisobstructivethromboticexternalhemorrhoidswererandomlyassignedtoreceiveeithertheherbalformulaoraplacebo.Aftereightweeksoftreatment,theresearchersfoundthattheherbalgrouphadsignificantlygreaterimprovementsinpain,bleeding,swelling,andothersymptomscomparedtotheplacebogroup.Noseriousadverseeffectswerereported.

AnotherstudypublishedintheJournalofTraditionalChineseMedicinein2014reportedsimilarfindings.Inthistrial,60patientswithbloodstasisobstructivethromboticexternalhemorrhoidswererandomlyassignedtoreceiveeithertheherbalformulaoraconventionalmedicationcalledDaflon.Afterfourweeksoftreatment,bothgroupsshowedsignificantimprovementsinsymptoms,buttheherbalgrouphadbetteroutcomesintermsofpain,bleeding,andinflammation.Theauthorsnotedthattheherbalformulamayofferasaferandmorecost-effectivealternativetoDaflon.

Whilethesefindingsarepromising,itisimportanttonotethatmoreresearchisneededtofullyunderstandtheeffectsandsafetyofDahuangMudandecoction.Manyfactorscaninfluencetheoutcomesofherbalmedicine,includingthequalityanddosageoftheherbs,thedurationoftreatment,andindividualvariationsinresponse.Giventhathemorrhoidscanbeachronicconditionthatrequiresongoingmanagement,itisimportantforpatientstoworkwithaqualifiedhealthcareproviderwhoisknowledgeableaboutChineseherbalmedicine.

InadditiontoDahuangMudandecoction,severalotherChineseherbalformulashavebeenusedforhemorrhoids,suchasXiaozhidecoction,LiuweiDihuangpill,andShenqiFuzhenginjection,tonameafew.Mostoftheseformulasconsistofmultipleherbsthatworksynergisticallytoaddresstheunderlyingimbalancesinthebody,ratherthantargetingisolatedsymptoms.SomeherbscommonlyusedintheseformulasincludeRadixSophoraeFlavescentis(Kushen),RadixSalviaeMiltiorrhizae(Danshen),andRadixAngelicaeSinensis(Danggui).

Itisworthnotingthatlikeanyformofmedicine,Chineseherbalmedicineisnotwithoutrisks.Someherbsmayinteractwithmedications,affectbloodpressureorbloodsugarlevels,orcauseallergicreactionsincertainindividuals.Therefore,itisimportanttoworkwithalicensedherbalistorhealthcareproviderwhocanguidepatientsthroughtheprocessofselectingandusingherbalremediessafelyandeffectively.

Inconclusion,DahuangMudandecoctionmayofferapromisingalternativeorcomplementaryapproachtoconventionalmedicaltreatmentsforpostoperativecomplicationsofbloodstasisobstructivethromboticexte