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HypertensionandObesityinChina

ProfessorsChenChunming&ZhaoWenhua(OnbehalfoftheWorkingGrouponObesityinChina,ILSIFocalPointinChina),ChineseCenterforDiseaseControlandPrevention,BeijingChinaHypertensionandObesityinCh1PartI:HypertensionriskatBMIandwaistcircumference(WC)levelsPartI:Hypertensionriskat2InternationalLifeScienceInstituteFocalPointinChina(ILSIFP-China)establishedaWorkingGrouponObesityinChina(WGOC)in2000.WGOCorganizedametaanalysisonthedatafrom13bigscalecross-sectionalsurveysince1990,underaprotocolforanalysisdatacollectedamong239,972adultsaged20-70wereincluded.DatasourceandanalysisInternationalLifeScienceIns3

Analysisondiseaserisksfactors,suchashighbloodpressure,diabetesincludingfastbloodglucose(FBG),serumcholesterol,HDL-C,triglycerides(TG),inrelationtoBMIandwaistcircumference(WC)wascarriedout.Metaanalysisofcohortstudiescovered4datasetswith76,227adultsubjectswasdone,theendpointsaretotalmortality,mortalityofcoronaryheartdisease,strokeandcancer,aswellasincidencesofcoronaryheartdiseaseeventsandstrokeevents.Partoftheresultsispresentedhere. Analysisondiseaserisksfac4

Theresultsontheprevalenceofhypertension,andclusteringofriskfactors(highbloodpressure,diabetesincludingfastbloodglucose(FBG),serumcholesterol,HDL,triglycerides)andBMIorwaistcircumference(WC)waspresentedasfollows.Theresultsontheprevalen5BMIandhighbloodpressureMaleMaleFemaleTheprevalenceofhypertensionincreasedwithincreasinglevelsofBMI.BMIandhighbloodpressureMal6WCandhighbloodpressureMaleFemaleTheprevalenceofhypertensionincreasedwithincreasinglevelsofWC

WCandhighbloodpressureMale7BMIandriskfactorclusteringMaleFemaleTheprevalenceof

clusteringofriskfactors

increasedwithincreasinglevelsofBMI.

BMIandriskfactorclustering8WCandriskfactorclusteringMaleFemaleTheprevalenceofclusteringofriskfactorsincreasedwithincreasinglevelsofWC.WCandriskfactorclusteringM9

Populationattributableriskpercent(%)ofhypertensionatBMIlevels

MaleFemaleOR*PARPORPARPBMI≥243.6945.92.7638.4BMI≥283.1711.52.6112.7*AgeadjustedPopulationattributabler10

Populationattributablerisk%ofhypertensionbeyondWCcutoffs

OR*PARPMenWC≥85cm3.4441.3WomenWC≥80cm3.3042.8*AgeadjustedPopulationattributabler11PartII:CorrelationanalysisofWC、BMIandbloodpressurePartII:Correlationanalysis12Datasourceandanalysis AstudywasconductedinAnhuiandHenanprovincesin1996byChenJunshiandZhaoWenhua. Totally11,815ruralresidentsaged40-79weresurveyedandinformationincludedbloodpressure,high,weightandwaistcircumference,dietandbloodsamplewerecollected.

TherelationshipbetweenWC、BMIandbloodpressurewasanalyzed.

Datasourceandanalysis13CorrelationanalysisofWC、BMIandbloodpressure(male)

CorrelationanalysisofWC、BMI14CorrelationanalysisofWC、BMIandbloodpressure(Female)

CorrelationanalysisofWC、BMI15Prevalence(%)ofhypertensionbyBMIgroup(male)*BMI%HPBMI、WCandPrevalenceofHypertensionPrevalence(%)ofhypertension16

Prevalence(%)ofhypertensionbyBMIgroup(Female)BMI%HP*

Prevalence(%)ofhypertensio17

Prevalence(%)ofhypertensionbyWCgroup(male)*

Prevalence(%)ofhypertensio18

Prevalence(%)ofhypertensionbyWCgroup(Female)*

Prevalence(%)ofhypertensio19CombinationofBMIandWC

inrelationtohypertensionprevalenceCombinationofBMIandWC

in20BMICombinationofBMIandWCinrelationtohypertensionprevalence(Male)BMICombinationofBMIandWCi21CombinationofBMIandWCinrelation

tohypertensionprevalence(Female)

BMIWhenWC≥75cm,prevalenceofhypertensionincreasedsignificantly(P<0.05).CombinationofBMIandWCinr22

Hypertensionprevalence%atvariousWClevels

withBMI≥24（male）*Hypertensionprevalence%at23Hypertensionprevalence%atvariousWClevels

withBMI≥24（female）*AtBMI≥24,WC≥80(male)WC≥75(female),prevalenceorhypertensiondramaticallyincreased(p<0.05forallgroups)Hypertensionprevalence%atv24

PartIII:SummaryandConclusion

DataindicatedapplicationofCombinationofBMIandWCwillbethebestpredictorforhypertensionrisk,recommendationwasmadetosetoverweightcutoffatBMI≥24;WC≤85formenand≤80cmforwomenasnormal.

25Applyingtheclassification,overweight(BMI≥24)prevalenceis30-40%,ifBMIcouldbecontrolledunder24,38-45%hypertensionofthispopulation,33-37%ofdiabetes,45-50%riskfactorclusteringmaybeprevented.Ifthe8-12%obesitypopulation(BMI≥28)couldbetreated,15-17%riskfactorclusteringcouldbeprevented.高血压和肥胖课件幻灯26THANKYOUTHANKYOU27HypertensionandObesityinChina

ProfessorsChenChunming&ZhaoWenhua(OnbehalfoftheWorkingGrouponObesityinChina,ILSIFocalPointinChina),ChineseCenterforDiseaseControlandPrevention,BeijingChinaHypertensionandObesityinCh28PartI:HypertensionriskatBMIandwaistcircumference(WC)levelsPartI:Hypertensionriskat29InternationalLifeScienceInstituteFocalPointinChina(ILSIFP-China)establishedaWorkingGrouponObesityinChina(WGOC)in2000.WGOCorganizedametaanalysisonthedatafrom13bigscalecross-sectionalsurveysince1990,underaprotocolforanalysisdatacollectedamong239,972adultsaged20-70wereincluded.DatasourceandanalysisInternationalLifeScienceIns30

Analysisondiseaserisksfactors,suchashighbloodpressure,diabetesincludingfastbloodglucose(FBG),serumcholesterol,HDL-C,triglycerides(TG),inrelationtoBMIandwaistcircumference(WC)wascarriedout.Metaanalysisofcohortstudiescovered4datasetswith76,227adultsubjectswasdone,theendpointsaretotalmortality,mortalityofcoronaryheartdisease,strokeandcancer,aswellasincidencesofcoronaryheartdiseaseeventsandstrokeevents.Partoftheresultsispresentedhere. Analysisondiseaserisksfac31

Theresultsontheprevalenceofhypertension,andclusteringofriskfactors(highbloodpressure,diabetesincludingfastbloodglucose(FBG),serumcholesterol,HDL,triglycerides)andBMIorwaistcircumference(WC)waspresentedasfollows.Theresultsontheprevalen32BMIandhighbloodpressureMaleMaleFemaleTheprevalenceofhypertensionincreasedwithincreasinglevelsofBMI.BMIandhighbloodpressureMal33WCandhighbloodpressureMaleFemaleTheprevalenceofhypertensionincreasedwithincreasinglevelsofWC

WCandhighbloodpressureMale34BMIandriskfactorclusteringMaleFemaleTheprevalenceof

clusteringofriskfactors

increasedwithincreasinglevelsofBMI.

BMIandriskfactorclustering35WCandriskfactorclusteringMaleFemaleTheprevalenceofclusteringofriskfactorsincreasedwithincreasinglevelsofWC.WCandriskfactorclusteringM36

Populationattributableriskpercent(%)ofhypertensionatBMIlevels

MaleFemaleOR*PARPORPARPBMI≥243.6945.92.7638.4BMI≥283.1711.52.6112.7*AgeadjustedPopulationattributabler37

Populationattributablerisk%ofhypertensionbeyondWCcutoffs

OR*PARPMenWC≥85cm3.4441.3WomenWC≥80cm3.3042.8*AgeadjustedPopulationattributabler38PartII:CorrelationanalysisofWC、BMIandbloodpressurePartII:Correlationanalysis39Datasourceandanalysis AstudywasconductedinAnhuiandHenanprovincesin1996byChenJunshiandZhaoWenhua. Totally11,815ruralresidentsaged40-79weresurveyedandinformationincludedbloodpressure,high,weightandwaistcircumference,dietandbloodsamplewerecollected.

TherelationshipbetweenWC、BMIandbloodpressurewasanalyzed.

Datasourceandanalysis40CorrelationanalysisofWC、BMIandbloodpressure(male)

CorrelationanalysisofWC、BMI41CorrelationanalysisofWC、BMIandbloodpressure(Female)

CorrelationanalysisofWC、BMI42Prevalence(%)ofhypertensionbyBMIgroup(male)*BMI%HPBMI、WCandPrevalenceofHypertensionPrevalence(%)ofhypertension43

Prevalence(%)ofhypertensionbyBMIgroup(Female)BMI%HP*

Prevalence(%)ofhypertensio44

Prevalence(%)ofhypertensionbyWCgroup(male)*

Prevalence(%)ofhypertensio45

Prevalence(%)ofhypertensionbyWCgroup(Female)*

Prevalence(%)ofhypertensio46CombinationofBMIandWC

inrelationtohypertensionprevalenceCombinationofBMIandWC

in47BMICombinationofBMIandWCinrelationtohypertensionprevalence(Male)BMICombinationofBMIandWCi48CombinationofBMIandWCinrelation

tohypertensionprevalence(Female)

BMIWhenWC

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