Rutin-trihydrate-Rutoside-trihydrate-DataSheet-生命科学试剂-MedChemExpress

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemERutintrihydrateCat.No.:HY-W013075CASNo.:250249-75-3Synonyms:Rutosidetrihydrate;Quercetin3-O-rutinosidetrihydrate分⼦式:C₂₇H₃₆O₁₉分⼦量:664.56作⽤靶点:Others作⽤通路:Others储存⽅式:4°C,sealedstorage,awayfrommoistureandlight*Insolvent:-80°C,6months;-20°C,1month(sealed

storage,awayfrommoistureandlight)溶解性数据体外实验DMSO:50mg/mL(75.24mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制备储备液1mM1.5048mL7.5238mL15.0476mL5mM0.3010mL1.5048mL3.0095mL10mM0.1505mL0.7524mL1.5048mL请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。储备液的保存⽅式和期限：-80°C,6months;-20°C,1month(sealedstorage,awayfrommoistureandlight)。-80°C储存时，请在6个⽉内使⽤，-20°C储存时，请在1个⽉内使⽤。BIOLOGICALACTIVITY⽣物活性Rutin(Rutoside)trihydrate⼀种多功能的天然酮苷，具有良好的抗氧化、抗炎、抗糖尿病和抗癌特性。Rutintrihydrate具有⼼脏保护和神经保护活性。体外研究Rutin(Rutoside)trihydrate(0.5-160μM/ml;PC12cells)decreasestheacrylamide(ACR)-induced(5.46mM)cytotoxicitysignificantly.ACR(5.46mM)decreasescellviabilityinPC12cellsandpretreatmentwithrutin1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemE(0.5,1,1.5,2.5,5,10,20and40μM/ml)increasesthecellviability[2].DuetotheabilityofRutinand/oritsmetabolitestocrossthebloodbrainbarrier,ithasalsobeenshowntomodifythecognitiveandvariousbehavioralsymptomsofneurodegenerativediseases[3].体内研究PretreatmentofRutin(100and200mg/kg/day;i.p.)forlong-termcausedbehaviouralandneurochemicalchangesinagedWAGmalerats[2].户使⽤本产品发表的科研⽂献•FoodChem.16December2021,131872.Seemorecustomervalidationsonwww.MedChemEREFERENCES[1].MelMMRD,etal.Formulationofmicroencapsulatedrutinandevaluationofbioactivityandstabilityuponinvitrodigestiveanddialysisconditions.IntJBiolMacromol.2020;159:316-323.[2].DoostkamA,etal.EffectofRutinonDiabeticAuditoryNeuropathyinanExperimentalRatModel.ClinExpOtorhinolaryngol.2021;14(3):259-267.[3].HabtemariamS.RutinasaNaturalTherapyforAlzheimer'sDisease:InsightsintoitsMechanismsofAction.CurrMedChem.2016;23(9):860-873.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseo