肝海绵状血管瘤英文·精品课件

肝脏海绵状血管瘤

CavernousHemangiomaofLiver

Outline

mostcommon

benign1%-20%indifferentplaceF〉M90%solitary

CavernousHemangiomaofLiverClinicalsymptomsMostofthemnevercause

symptomsorhealthproblems.andareincidentallydiscoveredatmedicalexamination,surgery,orautopsy(尸检).rightupperabdominalpain、pain,nausea(恶心)、enlargementoftheliver；

Pathologicalappearance

Cavernoushemangiomaisresultedfromendothelialcellsproliferation（增殖）.

Thetumorconsistsinlarge(cavernous)spaces,linedbytumorendothelialcells，Theseinterconnectedspacesarefilledwithbloodandseparatedbyafibroustissue。

Oralcontraceptives（口服避孕药）andsteroids(类固醇)may

acceleratethegrowthofahemangioma.Whetherornotthesedrugsactuallyinducetheformationofthehemangiomaisunclear.Causes+C20’’动脉期contrast-enhancedCTscanarterial

phaseThelesionappearsperipheralnodularenhancement（边缘结节状强化），thecenterofthelesiontypicallyremainshypodense.

+C5’延迟期

delayed

phase

The

wholelesionishomogeneousenhancement,thedensityis

higherorequaltothesurroundingnormalliver(sometumorshavelow-densitycenterwhichrepresentfibreorthrombus).

Diagnosis（MRI）T1WIT1WIsmooth,lobulated,homogeneous,sometimesseptatedhypointensemassrelativetotheliverNonenhancedMRIscansT2WImarkedlyhyperintensemass，

thesignalintensityofthelesionissimilartothatofthecerebrospinalfluid.‘lightbulb’sign灯泡征T2WIcontrast-enhancedMRIscan

Theseimagesdemonstratetheprogressive,centripetalcontrastenhancementinahemangioma.

早出晚归快进慢出o

hemangiomascandemonstrateimmediatehomogeneousenhancement(lesions<1.5cm)o

nodularcentripetalenhancementpatternprogressingtohomogeneity(lesions1.5-5cm)o

nodularcentripetalenhancementwithpersistentcentralhypointenseregion(lesions>5cm)

Differentialdiagnosis肝囊肿Hepaticcyst

原发性肝癌primaryhepaticcarcinoma

肝转移瘤

hepaticmetastatictumornonenhancement‘bulley