CYT-1010 - Mu-opioid Receptor Agonist - 生命科学试剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemECYT-1010Cat. No.: HY-123534CAS No.: 213769-33-6分式: CHNO分量: 624.73作靶点: Opioid Receptor作通路: GPCR/G Protein; Neuronal Signaling储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 125 mg/mL (200.09

2、 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 1.6007 mL 8.0035 mL 16.0069 mL5 mM 0.3201 mL 1.6007 mL 3.2014 mL10 mM 0.1601 mL 0.8003 mL 1.6007 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄的储备液

3、可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (3.33 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.08 mg/mL (3.33 mM); Clear solutionBIOLOGICAL ACTIVITY1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE物活性

4、CYT-1010种 mu-阿受体激动剂， 响 beta-arrestin 的募集和 cAMP 产抑制，EC50 值分别为 13.1nM、0.0053 nM，详细信息请参考专利献 WO2013173730A2 1。IC50 & Target EC50: 13.1 nM (beta-arrestin), 0.0053 nM (cAMP) 1REFERENCES1. Theodore E. Maione, Novel therapeutic uses of mu-opiate receptor peptides. WO2013173730A2.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 0