Hydroxyzine-dihydrochloride - Histamine Receptor Antagonist - 生命科学试剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEHydroxyzine dihydrochlorideCat. No.: HY-B0548ACAS No.: 2192-20-3分式: CHClNO分量: 447.83作靶点: Histamine Receptor作通路: GPCR/G Protein; Immunology/Inflammation; NeuronalSignaling储存式: 4C, protect from light* In solvent : -80C, 6 months;

2、-20C, 1 month (protect fromlight)溶解性数据体外实验 H2O : 150 mg/mL (334.95 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.2330 mL 11.1650 mL 22.3299 mL5 mM 0.4466 mL 2.2330 mL 4.4660 mL10 mM 0.2233 mL 1.1165 mL 2.2330 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存

3、式和期限。BIOLOGICAL ACTIVITY物活性 Hydroxyzine 双盐酸盐是组胺 H1 受体拮抗剂。REFERENCES1. Minogiannis, P., et al., Hydroxyzine inhibits neurogenic bladder mast cell activation. Int J Immunopharmacol, 1998. 20(10): p. 553-63.2. Dimitriadou, V., X. Pang, and T.C. Theoharides, Hydroxyzine inhibits experimental allergic en

4、cephalomyelitis (EAE) and associated1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEbrain mast cell activation. Int J Immunopharmacol, 2000. 22(9): p. 673-84.3. Kan, W.M., et al., Effect of hydroxyzine on the transport of etoposide in rat small intestine. Anticancer Drugs, 2001. 12(3): p. 267-73.4. Morichi, R. and G. Pepeu, A study of the influence of hydroxyzine and diazepam on morphine antinociceptoion in the rat. Pain, 1979.7(2): p. 173-80.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-589559