Flucytosine-5-Fluorocytosine-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEFlucytosineCat. No.: HY-B0139CAS No.: 2022-85-7Synonyms: 5-Fluorocytosine; NSC 103805; Ro 2-9915分式: CHFNO分量: 129.09作靶点: Fungal作通路: Anti-infection储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMS

2、O : 16.67 mg/mL (129.13 mM; Need ultrasonic)H2O : 6.67 mg/mL (51.67 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 7.7465 mL 38.7327 mL 77.4653 mL5 mM 1.5493 mL 7.7465 mL 15.4931 mL10 mM 0.7747 mL 3.8733 mL 7.7465 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药

3、式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 1.67 mg/mL (12.94 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 1.67 mg/mL (12.94 mM);

4、Clear solution1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 1.67 mg/mL (12.94 mM); Suspended solutionBIOLOGICAL ACTIVITY物活性 Flucytosine（5-Fluorocytosine, 5-FC, Ancobon）是抗真菌化合物。REFERENCES1. Vermes A, et al. Flucytosine: a review of its pharmacology, c

5、linical indications, pharmacokinetics, toxicity and drug interactions. JAntimicrob Chemother. 2000 Aug;46(2):171-9.2. Te Dorsthorst DT, et al. In vitro interaction of flucytosine combined with amphotericin B or fluconazole against thirty-five yeast isolatesdetermined by both the fractional inhibitory concentration index and the response surface approach. Antimicrob AgenMcePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;