Theaflavin _Influenza Virus 抑制剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemETheaflavinCat. No.: HY-N0243CAS No.: 4670-05-7分式: CHO分量: 564.49作靶点: Influenza Virus作通路: Anti-infection储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 H2O : 2 mg/mL (3.54 mM; Need ultrasonic and wa

2、rming)DMSO : 1.42 mg/mL (2.52 mM; Need ultrasonic and warming)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 1.7715 mL 8.8576 mL 17.7151 mL5 mM - - -10 mM - - -请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Theaflavin种天然的甲型流感 (H1N1) 神经氨酸酶抑制剂。IC50 & Target Influenza A (H1N1) v

3、irus 1体外研究Theaflavin, found in green tea, is observed to inhibit H1N1 NA proteins strongly supported by lowest dockingenergy. Theaflavin is a plant product traditionally used for treatment of influenza infection. Green tea is1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEparticularly rich in polyp

4、henolic compounds like Theaflavin. Theaflavin derivatives have shown pronouncedantiviral activity. Theaflavin is found to interact with the amino acid residues like Arg118, Asp151, Asp 152,Arg193, Asp199, Asn344, and Arg430 of NA by forming hydrogen bonds 1.REFERENCES1. Sahoo M, et al. Identification of Suitable Natural Inhibitor against Influenza A (H1N1) Neuraminidase Protein by Molecular Docking.Genomics Inform. 2016 Sep;14(3):96-103.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>