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1、重庆医科大学临床学院教案讲稿重庆医科大学临床学院教案及讲稿课程名称皮肤性病学年级2013级七年制授课专业皮肤性病学教 师赵恒光职称讲师授课方式大课示教学时 1题目章节 Contact Dermatitis 教材名称 Dermatovenereology 作者Liu Tong出版社Dean s office of Xi an Jiaotong University November 2004版次First教 学 目 的 要 求1. The definition of Contact Dermatitis.2. The etiology and pathogenesis of Contact De
2、rmatitisa.3. The clinical manifestations of Contact Dermatitis.教 学 难 点1. The etiology and pathogenesis of Contact Dermatitis.2. The clinical manifestations of Contact Dermatitis.3. The treatment of Contact Dermatitis.教 学 重 点1. The definition ofContact Dermatitis.2. The clinical manifestations and so
3、me special sorts of Contact Dermatitis.外语 要求熟练教学 方法 手段多媒体讲述、图谱展示、临床病例分析仝生 经支资料1 .中国临床皮肤病学赵辨等主编,2015年江苏科学技术出版社2 .Anderws Diseases of skin (第十版英文影印版)Richard.B.O等主编,科学出版社教研 室意 见教学组长:教研室主任:年月日教学内容辅助手段 时间分配制表时间:2005年10月7DefinitionContact Dermatitis3分钟Contact dermatitis is an exogenous dermatitis caused b
4、y substance coming in contact with the skin or/and mucosa.Etiology1. Irritant contact dermatitisDefinition: non immunological reaction.Alkalis: cement, ammonium hydroxideAcids: hydrochloric acid, etcSoaps and detergentsMetal salts: copper salts, cobalt salts, etcSolvents:benzene,toluene(methylbenzen
5、e),5分钟xylene, gasoline, etc2. Allergic contact dermatitisAnimals: Skins, hairs and featherPlants: -Lacquer tree, nettle, lemon, pine-appleChemicals:Metals and chemical materials: nickel salts, etcTopical medicine: antibiotics, antiseptic, etc.Cosmetics: hair dye, balsam, lipstick, etc.10分钟Clinical m
6、anifestations1. Irritant contact dermatits(1) Acute irritant contact dermatitisOften caused by strong acid, alkalis, etc.Clinical ManifestationMild reaction: transient erythema or erosion, Edema, inflammation, pain and vesicleSevere cases: exudation, bulla and necrosis(2) Cumulative Irritant Dermati
7、tisMost common typeEtiologyRepeat application of one or more irritantsA single exposure will not give any visible skin reactionManifestationErythema and increasing drynessHyperkeratosisChapping(fissures in the horny layer) to hemorrhagic fissure(crack into dermis)2. Allergic Contact Dermatitis12 分钟E
8、tiology: A prototype of the delayed hypersensitivity reaction (type IV allergic reaction).Stages of allergic contact dermatitisInduction phase(primary response): 4-7days after contact with allergenElicitation phase(secondary response): 2-4days to appearclinically recognized erythema, edema, and vesi
9、culationCommon symptomsErythemaPapulePapulovesicleSevere casesExtreme flare, vesicles and bullaNecrosisLesion only exist at contact areasDiagnosis5分钟Special contact historyContacting areas- clear boundaryClinical manifestationspatch test-Why: The simplest and most reliable teset for CD-When: 2w afte
10、r acute stageStop corticosteroids 1w and antihistamines 2d before test- Where: The forearm flexor side or back- How: Stick the suspicious substance under 1 layer of 4 cm2 gauze or small aluminum cell, 24 to 48 hours later remove and observe the skin reactions.- Result: (-)-(+) oTreatment- Avoidance
11、of the primary cause- Topical steroids will normally be required- Systemic steroids for more severe eczematous reactions:prednison 30-40mg/d- Antihistamine:Wet dressing for acute and exudative eczemacalamine lotion for actue stage without erosion and exudation5分钟小结1. Contact dermatitis is an exogeno
12、us dermatitis caused by substance coming in contact with the skin or/and mucosa.2. The Etiology of Allergic Contact Dermatitis: A prototype of the delayed hypersensitivity reaction (type IV allergic reaction). Stages of allergic contact dermatitis includes Induction phase(primary response): 4-7days
13、after contact with allergen; Elicitation phase(secondary response): 2-4days to appear clinically recognized erythema, edema, and vesiculation3. Diagnosis: Special contact history; Contacting areas- clear boundary; Clinical manifestations4. patch test- Why: The simplest and most reliable teset for CD
14、- When: 2w after acute stage, stop corticosteroids 1w and antihistamines 2d before test- Where: The forearm flexor side or back- How: Stick the suspicious substance under 1 layer of 4 cm2 gauze or small aluminum cell, 24 to 48 hours later remove and observe the skin reactions.-Result: (-) - (+) o思考 题及 预习1. What is the defenition of CD?2. What are the Etiology of Allergic Contact Dermatitis?3. What is the patch test and how to perform it?教案讲稿质量评价表权重评估
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