孟鲁司特对哮喘患儿血浆炎症因子和临床疗效作用

1、孟鲁司特对哮喘患儿血浆炎症因子和临床疗效作用【中图分类号】r256. 1【文献标识码】b【文章编 号】1672-3783 (2013) 11-0593-01【摘要】目的对应用孟鲁司特对患有哮喘的患儿实施 治疗的临床效果进行研究。方法抽取92例患有哮喘的患儿, 随机分为对照组和治疗组，平均每组46例。采用常规哮喘 治疗方案对对照组患儿实施治疗；在常规哮喘治疗方案基础 上加用孟鲁司特钠对治疗组患儿实施治疗。结果治疗组患 儿的哮喘病情治疗效果明显优于对照组；哮喘症状消失时间 和住院治疗总时间明显短于对照组；治疗前后血浆炎症因子 水平和fev1水平的改善幅度明显大于对照组；药物不良反 应率明显低于对照

2、组；治疗后病情再次复发人数明显少于对 照组。结论应用孟鲁司特对患有哮喘的患儿实施治疗的临 床效果非常明显。【关键词】孟鲁司特钠 哮喘治疗血浆炎症因子meng lusi , plasma inflammatory factors and clinical curative effect of children with asthmaabstract objective to apply meng lusi especially for the children with asthma to study the clinical effec t of t rea. tnient. met hods

3、 92 cases of children withasthma, were randomly divided into control group and treatment group, an average of 46 cases in each group. the conventional treatment of asthma treatment for children with the control group ； on the basis of conventional treatment of asthma and with meng lusi sodium in the

4、 treatment group with treatment resuits treatment group of children with asthma disease treatment effect is better than the control group； asthma symptoms disappear time and total time hospitalization obviously shorter than the control group ； before and after treatment plasma level of inflammatory

5、factor levels and fev1 has improved significantly greater than the control group； adverse drug reaction rate significantly lower than the control group ； iliness relapse again after treatment was significantly less than the control group. conclusionapplication of mengwith asthma therapy【key words 】l

6、usi especially for the children clinical effect is very obvious.meng lusi sodium asthma treatment plasma inflammatory factors儿童哮喘是由多种炎症细胞和炎症因子共同参与的一种以气道高反应性为主要特征表现的慢性气道炎症疾病 lo本次研究对患有哮喘的患儿在治疗过程中应用孟鲁司 特钠的临床效果进行研究。现汇报研究过程如下。1资料和方法1.1 一般资料在2010年11月-2012年11月抽取92例患有哮喘的患 儿，随机分为对照组和治疗组。对照组患儿中男25例，女 21例；患儿年龄6-14岁，平均年龄(10.4±1.7)岁；患病 时间6个月-7年，平均患病时间(2.8±1.5)年；治疗组患 儿中男27例，女19例；患儿年龄5-13岁，平均年龄 (10.2±1.8)岁；患病时间4个月-8年，平均患病时间 (2.9±1.3)年。本次研究对象在年龄、性别、患病时间等 自然指标方面进行组间比较p