Fumonisin-B1-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemEFumonisinB1(Standard)Cat.No.:HY-N6719RCASNo.:116355-83-0分子式:C₃₄H₅₉NO₁₅分子量:721.83作用靶点:Acyltransferase;Acyltransferase作用通路:MetabolicEnzyme/Protease储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 FumonisinB1(Standard)是FumonisinB1的分析标准品。本产品用于研究及分析应用。FumonisinB1是一种由Fusariummoniliforme产生的霉菌毒素。FumonisinB1是sphingosineN-acyltransferase(ceramidesynthase)的有效抑制剂，破坏鞘脂从头生物合成。FumonisinB1是最丰富和有毒的伏马菌素[1][2]IC50&Target SphingosineN-acyltransferase[2]REFERENCESHenryMH,etal.ThetoxicityoffumonisinB1,B2,andB3,individuallyandincombination,inchickenembryos.PoultSci.2001Apr;80(4):401-7.ShephardGS,etal.Disruptionofsphingolipidmetabolisminnon-humanprimatesconsumingdietsoffumonisin-containingFusariummoniliformeculturematerial.Toxicon.1996May;34(5):527-34.WangSK,etal.EffectoffumonisinB₁onthecellcycleofnormalhumanlivercells.MolMedRep.2013Jun;7(6):1970-6.HenryMH,etal.ThetoxicityoffumonisinB1,B2,andB3,individuallyandincombination,inchickenembryos.PoultSci.2001Apr;80(4):401-7.ShephardGS,etal.Disruptionofsphingolipidmetabolisminnon-humanprimatesconsumingdietsoffumonisin-containingFusariummoniliformeculturematerial.Toxicon.1996May;34(5):527-34.WangSK,etal.EffectoffumonisinB₁onthecellcycleofnormalhumanlivercells.MolMedRep.2013Jun;7(6):1970-6.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-589559