RS-AMPA-hydrochloride-racemic-AMPA-hydrochloride-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemE(RS)-AMPAhydrochlorideCat.No.:HY-100815ECASNo.:2922283-04-1Synonyms:(±)-AMPAhydrochloride分子式:C₇H₁₁ClN₂O₄分子量:222.63作用靶点:iGluR作用通路:MembraneTransporter/IonChannel;NeuronalSignaling储存方式:-20°C,sealedstorage,awayfrommoisture*Insolvent:-80°C,6months;-20°C,1month(sealedstorage,awayfrommoisture)溶解性数据体外实验DMSO:125mg/mL(561.47mM;Needultrasonic)SolventMass1mg5mg10mgConcentration制备储备液1mM4.4918mL22.4588mL44.9176mL5mM0.8984mL4.4918mL8.9835mL10mM0.4492mL2.2459mL4.4918mL请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。储备液的保存方式和期限：-80°C,6months;-20°C,1month(sealedstorage,awayfrommoisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。BIOLOGICALACTIVITY生物活性 (RS)-AMPA((±)-AMPA)hydrochloride是一种谷氨酸类似物，是一种有效的选择性兴奋性神经递质L-谷氨酸(L-glutamicacid)激动剂。(RS)-AMPAhydrochloride不会干扰海藻酸或NMDA受体的结合位点。REFERENCES1/2 MasterofBioactiveMolecules—您身边的抑制剂大师www.MedChemEHösliL,etal.EffectsoftheglutamateanalogueAMPAanditsinteractionwithantagonistsonculturedratspinalandbrainstemneurones.NeurosciLett.1983Mar28;36(1):59-62.SommerB,etal.Flipandflop:acell-specificfunctionalswitchinglutamate-operatedchannelsoftheCNS.Science.1990Sep28;249(4976):1580-5.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax:021