β-CGRP-mouse-Calcitonin-gene-related-peptide-2-mouse-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEβ-CGRP(mouse)Cat.No.:HY-P0203BSynonyms:Calcitoningene-relatedpeptide2(mouse);CGRPII(mouse)分⼦式:C₁₆₅H₂₆₅N₄₉O₅₅S₂分⼦量:3879.29Sequence:Ser-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Asp-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Leu-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asp-Val-Gly-Ser-Glu-Ala-Phe-NH2(Disulfidebridge:Cys2-Cys7)SequenceShortening:SCNTATCVTHRLADLLSRSGGVLKDNFVPTDVGSEAF-NH2(Disulfidebridge:Cys2-Cys7)作⽤靶点:CGRPReceptor作⽤通路:GPCR/GProtein;NeuronalSignaling储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性β-CGRP(mouse)⼀种能诱导⾎管舒张的降钙素因相关肽。β-CGRP(mouse)可⽤于⼼⾎管、促炎、偏头痛和代谢研究[1]。REFERENCES[1].WhitbyK,etal.Castanospermine,apotentinhibitorofdenguevirusinfectioninvitroandinvivo.JVirol.2005Jul;79(14):8698-706.[2].XuH,etal.TranscriptionalAtlasofIntestinalImmuneCellsRevealsthatNeuropeptideα-CGRPModulatesGroup2InnateLymphoidCellResponses.Immunity.2019Oct15;51(4):696-708.e9.[3].ArulmaniU,etal.Effectsofthecalcitoningene-relatedpeptide(CGRP)receptorantagonistBIBN4096BSonalpha-CGRP-inducedregionalhaemodynamicchangesinanaesthetisedrats.BasicClinPharmacolToxicol.2004Jun;94(6):291-7.[4].ParkSH,etal.Roleofα-CGRPintheregulationofneurotoxicresponsesinducedbykainicacidinmice.Peptides.2013Jun;44:158-62.[5].McLatchieLM,etal.RAMPsregulatethetransportandligandspecificityofthecalcitonin-receptor-likereceptor.Nature.1998May28;393(6683):333-9.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-58