Delphinidin-chloride-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEDelphinidinchloride(Standard)Cat.No.:HY-N2409RCASNo.:528-53-0分⼦式:C₁₅H₁₁ClO₇分⼦量:338.7作⽤靶点:Apoptosis;STAT;JAK;EGFR作⽤通路:Apoptosis;JAK/STATSignaling;StemCell/Wnt;Epigenetics;ProteinTyrosineKinase/RTK储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性Delphinidin(chloride)(Standard)Delphinidin(chloride)的分析标准品。本产品⽤于研究及分析应⽤。Delphinidinchloride⼀种可从浆果和红中分离得到的花素。Delphinidinchloride表现出内⽪依赖性⾎管舒张作⽤和抗癌活性。Delphinidinchloride还可以调节JAK/STAT3和MAPK信号传导，从⽽诱导HCT116细胞凋亡。Delphinidinchloride还EGFR的有效抑制剂(IC50:1.3μM)，可关闭下游信号级联。REFERENCES[1].NymanNA,et,al.Determinationofanthocyanidinsinberriesandredwinebyhigh-performanceliquidchromatography.JAgricFoodChem.2001Sep;49(9):4183-7.[2].AndriambelosonE,et,al.Naturaldietarypolyphenoliccompoundscauseendothelium-dependentvasorelaxationinratthoracicaorta.JNutr.1998Dec;128(12):2324-33.[3].ZhangZ,et,al.DelphinidinmodulatesJAK/STAT3andMAPKinasesignalingtoinduceapoptosisinHCT116cells.EnvironToxicol.2021May6.[4].MeiersS,etal.Theanthocyanidinscyanidinanddelphinidinarepotentinhibitorsoftheepidermalgrowth-factorreceptor.JAgricFoodChem.2001Feb;49(2):958-62.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:02