临床医学文献检索阅读评价与应用

临床医学文献检索、阅读、评价与应用

检索途径Medline检索保存和跟踪检索结果获取全文的途径其他途径Google题目英文关键词filetype:PDF联系作者论坛代理重要工具阅读的目的了解临床证据---CochraneLibrary，ClinicalEvidence，高IFSCI论文最新进展—Pubmed-Abstract研究方法—Methods讲演、兴趣—-精读了解背景---Introduction相互比较---Discussion评价质量---Methods文章的结构TitleandrunningtitleAuthorsandaddressesAbstractKeywordsandabbreviationsIntroductionMaterialsandmethodsResultsDiscussionAcknowledgmentsReferencesTablesandfigures

TitleAbstractFiguresTablesResultsanddiscussionRestofthepaper(J.K.Ladha)影响因子〔ImpactFactor〕发表文章篇数：2021=597，2021=577；合计=11742021年引用次数：2021=4341，2021=4122；合计=8463IF=8463/1174=7.2092021年6月中下旬公布文章质量评价Jadad评分CochraneHandbookCochraneBackReviewGroupCONSORT声明Jadad评分随机分组序列的产生方法2分：计算机或随机数字表1分：提到随机，但未详细说明0分：半随机或未随机双盲2分：描述了实施双盲的具体方法并且被认为是恰当的，如采用完全一致的抚慰剂等1分：试验仅提及采用双盲法0分：试验提及采用双盲，但方法不恰当，如比较片剂与注射剂而未提及使用双伪法退出与失访1分：详细说明了退出与失访的理由0分：没有提及CochraneBack

ReviewGroupFurlanAD,PennickV,BombardierC,vanTulderM,theEditorialBoardoftheCochraneBackReviewGroup.2021UpdatedmethodguidelinesforsystematicreviewsintheCochraneBackReviewGroup.Spine2021;34(18):1929–41.CONSORT清单详细内容引言BroadinformationontopicPreviousresearchNarrowerbackgroundinformationNeedforstudyFocusofpaperHypothesisandPurposeSurgeryisthetreatmentofchoiceforpatientswithdiseasestageIandIInon-smallcelllungcancer(NSCLC)…AnNSCLCmeta-analysiscombinedtheresultsfromeightrandomisedtrialsofsurgeryversussurgeryplusadjuvantcisplatin-basedchemotherapyandshowedasmall,butnotsignificant(p=0.08),absolutesurvivalbenefitofaround5%at5years(from50%to55%).Atthetimethecurrenttrialwasdesigned(mid-1990s),adjuvantchemotherapyhadnotbecomestandardclinicalpractice…Theclinicalrationaleforneo-adjuvantchemotherapyisthree-fold:regressionoftheprimarycancercouldbeachievedtherebyfacilitatingandsimplifyingorreducingsubsequentsurgery;undetectedmicro-metastasescouldbedealtwithatthestartoftreatment;andtheremightbeinhibitionoftheputativestimulustoresidualcancerbygrowthfactorsreleasedbysurgeryandbysubsequentwoundhealing…Thecurrenttrialwasthereforesetuptocompare,inpatientswithresectableNSCLC,surgeryaloneversusthreecyclesofplatinum-basedchemotherapyfollowedbysurgeryintermsofoverallsurvival,qualityoflife,pathologicalstaging,resectabilityrates,extentofsurgery,andtimetoandsiteofrelapse.CONSORT清单详细内容CONSORT清单详细内容〔续一〕CONSORT清单详细内容〔续二〕CONSORT清单详细内容〔End〕CONSORTGroup.CONSORT2021Statement:UpdatedGuidelinesforReportingParallelGroupRandomizedTrials.AnnInternMed.2021;152.DavidMoher,etal.CONSORT2021ExplanationandElaboration:updatedguidelinesforreportingparallelgrouprandomisedtrials.BMJ2021;340:c869评价对象例数n=排除例数n=例，不符合例，拒绝参与例，其它原因例。随机分组例数n=分配至实验组例数n=接受分配例,不接受分配例…分配至对照组例数n=接受分配例,不接受分配例…失访例数n=未依从计划例失访例数n=未依从计划例纳入分析例数n=排除分析例数n=纳入分析例数n=排除分析例数n=CONSORT流程图好文章的要求〔4C〕Clear：思路清晰、逻辑性强、概念清楚、层次清楚、表达清楚、语句通顺Complete：内容完整、结构完整，忌虎头蛇尾Correct：内容正确，数据数据正确、可信，文法