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TuberculosisofBoneandJiont
Tuberculosis(TB)isstillacommoninfectionindevelopingcountries.Afterlungandlymphnode,boneandjointisthenextcommonsiteoftuberculosisinthebody.Itconstituteabout1~4%ofthetotalcasesofTB.Childrenandyoungpeople(<30yearsold)are80%inthepeoplesofTB
Thespineisthecommonestsiteofboneandjoint,constitutingabout50%ofthetotalnumberofTBcases.
Thenextinorderoffrequenyarethehip,thekneeandtheelbow.TBosteomyelitiseffectstheendofthelongbone,unlikepyogenicosteomyelitiswhichaffectsthemetaphysis.Thejointconstitutedabout30%ofthetotalnumberofTBcases.
PathologyTBinfectionoftheboneandsynovialtissueproducessimilarresponseasitproducesinthelungesie.,chronicgranulomatousinflammationwithcaseationnecrosis.Theresponesmaybeproliferative,exudativeorboth.1、Proliferativeresponese:Itischaracterisedbychronicgranulomatousinflammationwithalotoffibrosis.
2、Exudativeresponese:thereisextensivecaseationnecrosiswithoutmuchcellularreaction.
3、CaseationnecrosisNaturalhistoryTheinflammationresultsinlocaltrabecularnecrosisandcaseation.Intheabsenceofadequatebodyresistenceorchemotherapy,thecorticesofthebonegeteroded,andtheinfectedgranulationtissuesandpusfindtheirwaytothesubperiostealandsoft-tissueplane.Heretheypresentascoldabscesses,andmayburstouttoformsinuses.1、Coldabscesses
2、Pathologicalfracture
3、Pannus.Inflammatorysynoviumattheperipheryofthecartilage.Atubercularosteomyelitisinthevicinityofajointmayresultintheinvolvementofthejoint.Lowgradesynovitiswiththickeningofsynovialmembrane.CartilagehavebeenSlowlydestruied.
4、Fibrousankylosis
5、healingInvestigation
1、X-rayexamination:TBosteomylitis、TBarthritis.
2、Bloodexamination
3、SerumELLSAtestforantibodies
4、Synovialfluidaspiration
5、Aspirationofcoldabscess
6、HistopathologicalexaminationfrombiospyorcurettageofalesionTreatment1、Controlofinfection:Anti-TbdrugsincludingRifampicin,INH,thambutol,Pyrazinamide,Strptomycin.Rest.2、Careoftheaffectedpart:ProperpositionofthejiontMobilisationExerciseWeight-bearing:itisstartedgraduallyastheosteoporosissecondarytothediseaseisreversed3、Operativeintervention
Biospy
Treatmentofthecoldabscess
Curettageoftheleision
Jiontdebridement
Synovectomy
Salvageoperations
Decompression
TBofthespineThespineisthecommonestsiteofboneandjiontTB;Thedorso-lumbarregionbeingtheoneaffectedmostfrequentlyTypeofvertebraltuberculosisParadiscalCentralAnteriorPosteriorPathologyThebasicpathologyisthesameasthatinotherboneandjiontTB.Cllopseofthevertebra.Gennerallywedging.ColdabscessClincalfeaturesPainbackpainisthecommonestsyptom.Stiffnesspara-vertebalmusclegointospasmtopreventmovement.ColdabscessParaplegiaDefomitygibbusConstitutionalsymptomfever,weight-lossPhysicalexaminationGaitshortsteptoavoidjerkingthespineAttitudeanddiformityPatientwithcervicalTBhasastiff,straightneck.IndorsalspineTB,thespinebecomeprominent.Para-vertebralswellingTendernessMovementspinemovementislimited.Neurologicalexaminationlevel,severityGeneralexaminationinvestigationX-rayDestructionofthevertebralbody,coldabscess,rarefaction.CTscanMRIBiopsyGeneralinvestigationESR,CRP,TBIGg,ELLSAtest,chestX-raycomplication1、Coldabscess2、Neurologicalcompression(pottparaplegia)Treatment1、stable2、reconstractePrinciplesoftreatmentPrinciplesoftreatmentTopromoterecoveryoftheaffectedneuraltissue,byreversingthecauseresponsibleforcompression,eitherbydrugorbyoperation.Toachivehealingofthevertebrallesion,andtosupportthespinetillthediseasesegmentbecomestable.Decompression.Toundertakerehabilitativemeasurestopreventcontracture,andtoregainstrenghintheaffectedpart.1、Conservativetreatment
drug
2、Operation
debride
decompression
stablespineTuberculosisofthehipPathologyThebasicpathologyissame.Theusualintialisintheboneadjacenttothejionti.e.,eithertheacetabulumortheheadofthefemur.Insomecases,thelesionbegininthesynovinm,butthecartilageandthebonesareaffected.ApurelysynovialTBasseenintheknee,isuncommominthehip.Naturalhistory1、Thesynoviumhypertrophyandeffusion.Thecartilageisdestroyedandthejointbecomefullofpusandgranulationtissues.Thesynoviumgetthickened,oedematous,grayandulcerated.2、MulpiplecavitationSuchcavitiesareformedinthefomralheadandtheacetabulum.Eventuallytheheadandacetabulumgetobsorbed.Thejointdislocatedandtheneckoffomralgetfracture.Thepusmayperforatetheacetabulumandappearasapelvicabscess.3、Healingmaytakeplacebyfibrosis,leadingtoankylisisofthehipinadeformedposition.Clinicalfeature
1、Stiffnessofthehip,itproducesalimp.
2、Pain.Itmaybepainreferredtotheknee.Thechildmaycomplainofnightcry.Thomas征PE:Stiff-hipgait.Lamenessisthefirstsign.MusclewastingSwellingDischargingsinusesDeformityShorteningMovementsactiveandpassivemovementarelimited.StageofTBofthehipStageofsynovitisThereiseffisionintothejiont.Thisstageiscalledthestageofapparentlengthening.StageofthearthritisThisstageiscalledthestageofapparentshortening.StageoferosionThecartilageisdestroyedandtheheadortheacetabulumiserosion.Investigation
X-rayHaziness,Lyticlesion,reductionofjiontspace,Irregularoutline,Acetabularchange.RoutinalinvestigationbiospyPrincipleofTreat
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