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杨雄里院士神经生物学家,1963年上海科技大学生物系毕业,1963-1999年在中国科学院上海生理研究所工作,历任研究实习员、助理研究员、副研究员、研究员、所长。1980-1982年在日本进修并获学术博士学位。1985-1987年先后在美国哈佛大学、贝勒医学院从事合作研究。2000年创建复旦大学神经生物学研究所并任所长。曾任中国生理学会理事长,亚太地区生理学联合会第一副主席。长期从事视觉神经机制的研究,在几个层次上对视网膜中的信息传递的调控进行系统研究并有数项新发现。1989年获中科院自然科学一等奖,1991年当选为中国科学院院士,2001年获何梁何利科技进步奖。现为ProgressinNeurobiology等国内外学术刊物编委或主编。根据所给的研究结果(确实有困难的同学可自选一篇论文):1.为该论文拟一个标题并撰写论文前言、材料和方法、结果、讨论部分的概要(i.e.outline:限前言不多于4句、材料和方法不多于5个标题、结果不多于6句、讨论不多于5句)。2.为该论文选一个最适合的杂志,按照该杂志的投稿要求,以你的名义和通讯作者的身份给该杂志写一封全真(除了不用邮寄给该杂志)的投稿信(coverletter),投稿信写法可参照参考书和鲁白教授的ppt.3.按照所投稿杂志的要求撰写论文摘要(可不做)(自选论文的同学请附所依据的论文全文)写下你认为最好的一个报告的报告人的名字(本学期最佳被告人).写好姓名和学号打印,2006年1月4日前交西7号楼160/168陈晓青)。日后本作业所依据的论文全文和所发表的杂志等信息将上载到课程网页上供大家参考.作业二科研论文撰写和送审过程中导师和学生的互动杨雄里复旦大学神经生物学研究所导师与学生对第三稿进行讨论后,由导师拟就第四稿,交回学生再评论和修改。对学生的评论和修改意见作认真考虑后,拟就第五稿(半定稿),请学生评论、修改。导师最后定稿(第六稿),并对英文作仔细润色。由学生严格按投寄杂志的要求整理定稿、送审。本研究室科研论文撰写的程序杂志主编对送审论文的说明信(coverletter)四种类型不作任何修改即表示接收。表示接收的意图,但指出需作修改。不明确表示“收”或“拒”。退稿。From:"NeuroReport"<nr@lww.co.uk>

To:<xlyang@>

Sent:Wednesday,June18,20036:19PM

Subject:NeuroReport:DecisiononVoltage-gatedK+channelsubunitsoncholinergicanddopaminergicamacrinecells

18Jun2003

DearDr.Yang,

Submissionno.:NR-D-03-00757

Articletitle:Voltage-gatedK+channelsubunitsoncholinergicanddopaminergicamacrinecells

Correspondingauthor:Dr.Xiong-LiYang

YourpaperhasbeenseenbyourreviewersandIhavereceivedfromtheSectionEditorafavourablerecommendation.IampleasedtoletyouknowthatwewillthereforepublishitinthenextissueofNeuroReporttobecompiled.Thereisnospecificcriticismofthepaperandnorequestsofrevision(andthismakesamostpleasantandunusualchangefromourroutine;congratulations!).

Adecisionisnotyetbeenmadeonthecoveroftheissuebutwewilltakeintoconsiderationthefigurethatyouareofferingforthepurpose.Ifyourpictureischosen(thechancesarehigh),Iwillneedanadhocfigurelegend,thatcouldbereadandunderstoodwithoutdirectreferencetothepaperitself;itcouldbequitelong,butithastobeextremelyclear.Willyouhaveagoatit?.

ThankyouforsendingthisinterestingpapertoourJournal.

Kindregards.

Yourssincerely,

GiorgioGabella,MDDSc

EditorinChief

NeuroReport

LocalizationofKvsubunitsinretinalamacrinecells

CholinergicDopaminergicKv3.1bKv4.3回复论文评审意见的程序导师和学生对评审意见逐条进行讨论,决定如何答复,是否需作补充实验。由学生拟出答复意见。Zhang,D.Q.andYang,X.L.(1998)GABAmodulatescolor-opponentbipolarcells.BrainRes.,792:319-323.Lu,T.Shen,Y.andYang,X.L.(1998)DesensitizationofAMPAreceptorsonhorizontalcellsisolatedfromcruciancarpretina.NeurosciRes.,31:123-135.Shen,Y.andYang,X.L.(1999)ZincmodulationofAMPAreceptorsmayberelevanttosplicevariantsincarpretina.NeuroscienceLett.,259:177-180.Shen,Y.,Lu,T.andYang,X.L.(1999)ModulationofdesensitizationatglutamatereceptorsinisolatedcruciancarphorizontalcellsbyconcanavalinA,cyclothiazide,aniracetamandpepa.,Neuroscience,89:1979-1990.Zhang,D.Q.,Yang,R.andYang,X.L.(1999)SuppressionofsustainedandtransientonsignalsofamacrinecellsbyGABAismediatedbydifferentreceptorsubtypes.ScienceinChina,Ser.C.42:395-400.Zhang,J.andYang,X.L.(1999)GABAbreceptorsinMullercellsofthebullfrogretina.NeuroReport,10:1833-1836.Li,P.,Yang,X.L.(1999)Zn2+differentiallymodulatesglycinereceptorsversusGABAreceptorsinisolatedcarpretinalthird–orderneurons.NeuroscienceLett.,269:75-78.Han,M.H.andYang,X.L.(1999)Zn2+differentiallymodulateskineticsofGABAcvsGABAareceptorsincarpretinalbipolarcells.NeuroReport,10:2593-2597.Yang,X.L.Gao,F.andWu,S.M.(1999)ModuationofhorizortalcellfunctionbyGABAaandGABAcreceptorsindark-andlight-adaptedtigersalamanderretina.VisualNeuroscience.16:1-13.Publications(1998~Present)Yang,X.L.Shen,Y.,Han,M.H.andLu,T.(1999)PhysiologicalandPharmacologicalCharacterizationofGlutamateandGABAReceptorsintheRetina.KoreanJournalofPhysiologyandPharmacology,3:461-469.Du,J.L.andYang,X.L.(1999)Retinalbipolarcell——Amodelforthestudyofneuronalsignalintegration.ChineseScienceBulletin.44:1737-1743.Yang,X.L.,Shen,Y.andHan,M.H.(1999)Glutamateandγ-aminobutyricreceptorsandtheircharacteristicsinretina.ChineseScienceBulletin,44:1548-1556.Yang,X.L.Gao,F.andWu,S.M.(1999)ModulationofhorizortalcellfunctionbyGABAaandGABAcreceptorsindark-andlight–adaptedtigersalamanderretina.VisualNeuroscience.1-13.Shen,Y.,andZhou,Y.andYang,X.L.(1999)CharacterizationofAMPAreceptorsonisolatedamacrine-likecellsincarpretina.Eur.J.Neurosci.,11:4233-4240.Xu,H.P.andYang,X.L.(1999)DifferentialmodulationbyGABAofsignalsfromred–andgreen–sensitiveconesinthecarpretina.BrainResBul.,51:493-497.Zhao,J.W.,Du,J.L.,Li,J.S.andYang,X.L.(2000)ExpressionofGABAtransportersonbullfrogretinalMüllercells.Glia31:104-117Du,J.L.andYang,X.L.(2000)SubcellularlocalozationandcomplementsofGABAAandGABAcreceptorsonbullfrogretinalbipolarcells.J.Neurophysiol.,84:666-676Xu,H.P.,Zhao,J.W.andYang,X.L.(2003)Cholinergicanddopaminergic

amacrinecellsdifferentiallyexpresscalciumchannelsubunitsintheratretina.Neuroscience,118:763-768.Tian,M.,Chen,L.,Xie,J.X.,Yang,X.L.andZhao,J.W.(2003)Expressionpatternsofinwardlyrectifyingpotassiumchannelsubunitsinratretina.

Neurosci

Lett.,345:9-12.Tian,M.,Xie,J.X.,Zhao,J.W.andYang,X.L.(2003)Differentialexpressionofvoltage-gatedpostssiumchannelsubunitsoncholinergicanddopaminergic

amacrinecellsinratretina.NeuroReport,14:1763-1766Li,G.L.andYang,X.L.(2003)Glycinergicinputtocarpretinalganglioncellsmaybemediatedbyglycinereceptorswithhomologouskinetics.

BrainRes.,991:171-179Shen,Y.Zhang,A.J.andYang,X.L.(2003)Uncouplingofhorizontalcellsaltersthereceptivefieldsofretinalbipolarcells.NeuroReport,14:2159-2163Huang,H.,Luo,D.G.,Shen,Y.,Zhang,A.J.,Yang,RandYang,X.L.(2004)AMPAreceptorisinvolvedintransmissionofconesignaltoONbipolarcellsincarpretina.BrainRes.,1002:86-9340.Huang,H.,Luo,D.G.,Shen,Y.,Zhang,A.J.,Yang,RandYang,X.L.(2004)AMPAreceptorisinvolvedintransmissionofconesignaltoONbipolarcellsincarpretina.BrainRes.,1002:86-9341.Yang,X.L.,(2004)CharacterizationofreceptorsforglutamateandGABAinretinalneurons.ProgressinNeurobiology.73:127-150Du,J.L.,Yang,X.L.(2002)Bullfrogretinalbipolarcellsmayexpressheterogeneousglycinereceptorsatdendritesandaxonterminals.NeuroscienceLetters322:177-181.Yang,X.L.,Fan,GandWu,S.M.(2002)Non-linear,high-gainandsustained–to-transientsignaltransmissonfromrodstoamacrinecellsindark-adaptedretinaofAmbystoma.J.Physiol.,539:239-251.Du,J.L.,Yang,X.L.(2002)Glycinergicsynaptictransmissiontobullfrogretinalbipolarcellsisinput-specific.Neuroscience,113:779-784.Xu,H.P.,Zhao,J.W.,Yang,X.L.(2002)Expressionofvoltage-dependentcalciumchannelsubunitsintheratretina.Neurosci.Lett1.

329:297-300.Luo,D.G.,Li,G.LandYang,X.L(2002)Zn2+modulateslightresponsesofcolor-opponentbipolarandamacrinecellsinthecarpretina.BrainRes.Bull.,

58:461-468.Xu,H.P.,Yang,X.L.(2002)DifferenteffectsoflowCa2+onsignaltransmissionfromrodsandconestobipolarcellsincarpretina.BrainRes.,957:136-143.Luo,D.G.,Yang,X.L.(2002)SuppressionbyzincoftransientOFFresponsesofcarpamacrinecellstoredlightismediatedbyGABAAreceptors.BrainRes.,958:222-226.Du,J.L.,Xu,L.Y.,andYang,X.L.(2002)GlycinereceptorsandtransportersonbullfrogretinalMüllercells.NeuroReport.13:1653-1656.42.Cao,L.H.,Yu,Y.C.,Zhao,J.W.,andYang,X.L.(2004)ExpressionofnatriureticpeptidesinratMullercells.Neurosci.Lett.365:176-17943.Chen,L.,Yu,Y.C.,Zhao,J.WandYang,X.L*(2004)Inwardlyrectifyingpotassiumchannelsinratretinalgangli

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