心脏康复评定

心脏康复评定第1页/共93页CARDIOVASCULAREVALUATIONDR.LiangQi第2页/共93页APATIENTCASEEXAMPLE第3页/共93页1.Whyareyouheretoday?2.Haveyoubeendiagnosedwithacardiacdisorderinthepast?3.Haveyouhadanyspecialteststoexamineyourheartlikeanelectrocardiogram,stresstest,echocardiogram,orcardiaccatheterization?第4页/共93页4.Doyouexperienceanginaorshortnessofbreathatrest,onlywithactivity/exercise,orbothatrestandwithactivity/exercise?第5页/共93页5.Ifyouexperienceanginaorbecomeshortofbreathduringactivityorexercisecouldyoupleasedescribethetypeofactivityorexercisewhichproducesyouranginaorshortnessofbreath?第6页/共93页6.Canyoudescribeyouranginaorshortnessofbreath?Canyouhelpmeunderstandyouranginaorshortnessofbreathbypointingtothenumbers1through4todescribethelevelofanginayouexperienceatrestandexerciseorbypointingtoyourlevelofshortnessofbreathusingthis10-pointscaleorbymarkingthisvisualanalogscale?第7页/共93页7.CouldIfeelyourpulsetodetermineyourheartrateandthestrengthofyourpulse?8.CouldIplacethisfingerprobeonyourindexfingertoobtainanoxygensaturationmeasurement?第8页/共93页9.CouldIplacetheseelectrodesonyourchesttoobtainasimplesingle-leadelectrocardiogram(ECG)?第9页/共93页10.CouldItakeyourbloodpressurewhileyouareseatedandthencompareittothebloodpressurewhileyouarelyingdownandthenstanding?Iwouldalsoliketoobserveyourpulse,oxygensaturation,ECG,andsymptomswhenyouarelyingdownandstanding.第10页/共93页11.CouldIlistentoyourheartandlungswithmystethoscope?WhileIdothisIwillconcentrateonwatchingyourECGsothatIcanidentifyyourheartsoundsandanychangesintheECGwhileyouarebreathingdeeplywhenlisteningtoyourlungs.第11页/共93页12.CouldIplace1ofmyhandsonyourstomachand1handonyourupperchesttodeterminehowyoubreathe?13.CouldIplacemyhandsonthelowermostribsoneachsideofyourchesttodeterminehowyoubreathe?14.CouldIplacemyhandsonyourbacktodeterminehowyoubreathe?15.CouldIwrapmytapemeasurearoundyourchestatseveraldifferentsitestodeterminehowyoubreathe?第12页/共93页16.NowthatIunderstandsomeverybasicinformationaboutthemannerinwhichyoubreathecouldyoupleasebreatheinthemannerIinstructyouviasoundsImake,pressurefrommyhands,methodsIshowtoyou,ordifferentbodypositions?IwilloccasionallyplacemyhandsonyourchestandwrapmytapemeasurearoundyourchesttodeterminehowyoubreatheduringthesesimpletestsandIwillaskyoutoidentifyyourlevelofshortnessofbreathusingthe10-pointscaleorvisualanalogscale—Isthisokwithyou?第13页/共93页17.CouldImeasurethestrengthofyourbreathingmusclebyhavingyouplacethismouthpieceinyourmouthandbreatheinandoutasdeeplyandasforcefullyasyouareable?第14页/共93页18.Iwouldlikeyoutonowperformtheactivityorexercisewhichproducesyouranginaorshortnessofbreath.Couldyoupleasedothisnow?第15页/共93页Thankyouforgivingmethechancetoexamineyoutoday.Iwillcallyourphysiciantogetsomemoreinformationaboutyoulikeelectrocardiogram,echocardiogramandpulmonaryfunctionteststhatyousaidwereperformedlastweekaswellasthearterialbloodgasresults,chestX-ray,andexercisetestresults.第16页/共93页PhysicalTherapyExaminationMedicalInformationandRiskFactorAnalysis

listeningtothepatientspasthistoryandprimarycomplaintsiscriticalintheexaminationprocess.

第17页/共93页ExaminationsofPatientAppearancecategorizedbyspecificsignsandsymptoms第18页/共93页Angina-MethodsToEvaluateAnginafromNonanginalPainIfasuspectedanginalpainchanges(increasesordecreases)withbreathing,palpationinthepainfularea,ormovementofajoint(ie,shoulderflexionandabduction)itisverylikelythatthepainisNOTangina.第19页/共93页Angina-MethodsToEvaluateAnginafromNonanginalPainitcanbeworsenedbyphysicalexerciseoractivity.Therefore,ifthesuspectedanginalpainisunchangedwiththepreviouslycitedmaneuversandthepainoccurredwithexertion,itisSUSPECTforangina.Ifthesuspectedanginalpainisunchangedbythesemaneuvers,ifthepainoccurredwithexertion,andifthepaindecreasesorsubsideswithrest,itisverylikelythatthepainISangina.Finally,ifthesuspectedpaindecreasesorsubsideswithnitroglycerin,itisevenmorelikelythatthepainISangina.第20页/共93页第21页/共93页"Other"SymptomsofHeartDiseasedyspneaFatigueDizzinessLightheadednessPalpitationsasenseofimpendingdoom第22页/共93页第23页/共93页ExaminationsofPatientAppearanceskincoloroftheperipheralextremities.Paleorcyanoticskininthelegs,feet,arms,andfingersisassociatedwithpoorcardiovascularfunction.第24页/共93页ExaminationsofPatientAppearanceDiagonalearlobecrease.Thisphenomenonhasbeeninvestigatedformanyyearsandrecentlywasonceagainfoundtobehighlypredictiveofheartdisease第25页/共93页AnthropometricmeasurementsbodyweightfingerpressureonanedematousareaGirthmeasurementsskin-foldcalipermeasurementscalculationofthebodymassindexmeasurethepercentageofbodyfatandleanmusclemass第26页/共93页Jugularvenousdistensionitisoftenduetoright-sidedheartfailure.第27页/共93页第28页/共93页第29页/共93页PalpationoftheRadialPulsePalpationoftheradialpulsecanprovideimportantinformationaboutthestatusofthecardiovascularsystem.MeasurementoftheSystolicBloodPressureandPulseDuringBreathingandSimplePerturbationsoftheBreathingCycle第30页/共93页MeasurementoftheSystolicandDiastolicBloodPressureandPulseinDifferentBodyPositions第31页/共93页

ToDeterminetheStatusoftheCardiovascularSystem

observationofadecreaseinsystolicanddiastolicbloodpressurewithoutasubsequentincreaseinheartratewhenchangingbodypositionfromsupinetostandingisconsideredapositivesignforautonomicnervoussystemdysfunction..第32页/共93页ToDeterminethe

HealthoftheCardiovascularSystemAcardiovascularsystemthatrespondsrapidlytobodypositionchangeislikelyinabetterstateofhealththanacardiovascularsystemthatrespondssluggishly.Bothanunchangedordecreasedheartrateafterstandingfor30seconds(comparedtotheheartrateat15seconds)issuggestiveofautonomicdysfunction.第33页/共93页asluggishorhypoadaptive(lessthannormal)heartrateandbloodpressureresponseduringachangeinbodypositionsupinetostandingshouldbeconsideredabnormalandsuggestiveofanunhealthycardiovascularsystem.第34页/共93页amoreadaptiverapidincreaseinheartrateandbloodpressureaftermovingfromasupinetostandingposition(approximately30seconds)islikelyassociatedwithahealthiercardiovascularsystem第35页/共93页ExaminationofthePulseandArterialBloodPressure

DuringFunctionalTasksandExerciseFrequentmonitoringoftheheartrateandbloodpressuremaybethebestwaytoexaminethesafetyofexerciseandhelptoestablishguidelinesandproceduresforfunctionalorexercisetraining.第36页/共93页anincreaseinthediastolicbloodpressurewhenthediastolicbloodpressureshouldbedecreased(orlow)isastrongindicatorofcardiovasculardysfunction..第37页/共93页PotentialindirectmeasuresofcardiacfunctionSymptomsandfunctionalclassificationCold,pale,andpossiblycyanoticextremitiesJugularvenousdistensionandperipheraledemaHeartsoundsPulseElectrocardiographyBloodpressure第38页/共93页StandardmeasurementofcardiacfunctionCardiaccatheterizationEchocardiographySwan-GanscatheterizationCentralvenouspressureCardiacenzymesANPandBNPRadiologicevidence第39页/共93页ExerciseTesting第40页/共93页IndicationsforExerciseTesting:DiagnosisofCoronaryArteryDiseaseAssessmentofPrognosisinCoronaryArteryDiseaseEvaluationofFunctionalCapacityEvaluationofTherapyforCoronaryDiseaseDeterminationofExercisePrescription第41页/共93页AbsoluteContraindicationstoExerciseTestingAcuteMI(within2days)High-riskunstableanginaUncontrolledcardiacarrhythmiasActiveEndocarditisSevereaorticstenosisDecompensatedheartfailureAcutepulmonaryembolusorinfarction,DVTAcutenoncardiacdisorderaffectingoraggravatedbyexerciseAcutemyocarditis,pericarditisPhysicaldisabilityprecludessafeandadequatetestInabilitytoobtainconsent第42页/共93页RelativeContraindicationstoExerciseTestingLeftmaincoronarystenosisorequivalentModerateaorticvalvularstenosis(?)ElectrolytedisorderTachyarrhythmiasorBradyarrhythmiasAtrialfibrillationwithuncontrolledventricularresponseHypertrophicCardiomyopathy(?gradient)MentalimpairmentleadingtoinabilitytocooperateHigh-degreeAVblock第43页/共93页ECGLeadPlacementfor

ExerciseTesting第44页/共93页ProtocolsforExerciseTesting第45页/共93页BloodPressureResponses:

ExerciseTestingDependencyoncardiacoutputandperipheralresistanceNormalresponses:IncreaseinSBP(>20-30mmHg)NochangeorfallinDBPInadequateriseinSBP:Myocardialischemia,severeLVsystolicdysfunction,aorticorLVOTobstruction,drugtherapy(ß-blockers)Exercise-InducedHypotension(>10mmHgbelowbaseline)Severemyocardialischemia(50%positivepredictivevalueforleftmainor3-vesseldisease),valvularheartdisease,cardiomyopathynoevidenceofclinicallysignificantheartdisease(dehydration,antihypertensivetherapy,prolongedstrenuousexercise)第46页/共93页HeartRateResponsetoExerciseTestingAcceleratedHeartRateResponse:Deconditioning,prolongedbedrest,anemia,metabolicdisorders,conditionsassociatedwithdecreasedbloodvolumeorlowsystemicvascularresistance,autonomicinsufficencyChronotropicincompetence:Inadequateexerciseeffort,drugtherapy(ß-blockers),PrognosticSignificance:(PeakHR-RestingHR)/(220-age-RestingHR)<0.80(Lauer,1999)PeakHR<130bpm(Ellestad)第47页/共93页EvaluationofExerciseEffortduringExerciseTesting:TheBorgPerceivedExertionScale第48页/共93页ExerciseCapacity-ExerciseTestingMETcapacity1MET=3.5ml/kg/minO2consumptionFunctionalAerobicImpairment(FAI) (BruceProtocolspecific)PredictedMETlevel(nomograms)PredictedVO2(ACSMformulae)PracticalAspects:LackofassociationbetweenLVEFandexercisecapacityPrognosticvalueofdecreasedexercisecapacityandactiveCADPredictorofpatient’sdisability第49页/共93页ExerciseTesting-ComplicationsMIordeath:Upto10per10,000tests(1per2,500)Lifethreateningventriculararrhythmias:0-5per100,000Cardiac:Bradyarrhythmias,tachyarrhythmias,acutecoronarysyndromes,heartfailure,hypotension,syncope,deathNoncardiac:Musculoskeletaltrauma,soft-tissueinjuryMiscellaneous:Severefatigue,dizziness,myalgias第50页/共93页AbsoluteIndicationsforTerminationofExerciseTestST-segmentelevation(>1.0mm)inleadswithoutQ-waves(otherthanV1oraVR)Dropinsystolicbloodpressure>10mmHg(persistentlybelowbaseline)despiteanincreaseinworkload,whenaccompaniedbyanyotherevidenceofischemiaModeratetosevereangina(grades3-4)Centralnervoussystemsymptoms(ataxia,dizziness,nearsyncope)Signsofpoorperfusion(cyanosisorpallor)SustainedventriculartachycardiaTechnicaldifficultiesmonitoringtheECGorsystolicBPPatient’srequesttostop第51页/共93页RelativeIndicationsforTerminationofanExerciseTestSTchanges(horizontalordownsloping>2mm)ormarkedaxisshiftDropinsystolicbloodpressure>10mmHg(persistentlybelowbaseline)despiteanincreaseinworkload,intheabsenceofotherevidenceofischemiaandnopresyncopalsymptomsIncreasingchestpainFatigue,shortnessofbreath,wheezing,legcramps,orclaudicationHypertensiveresponse(SBP>250mmHgand/orDBP>115mmHg)Developmentofbundle-branchblock(LBBB)thatcannotbedistinguishedfromventriculartachycardia;?EvidenceofanteriorischemiaArrhythmiasotherthansustainedventriculartachycardia(frequentmultifocalPVC’s,ventriculartriplets,SVT,heartblock,orbradyarrhythmias)GeneralAppearance(diaphoresis,peripheralcyanosis)第52页/共93页CriteriaforReadingST-SegmentChangesontheExerciseECGSTDEPRESSION:Measurementsmadeon3consecutiveECGcomplexes!STlevelismeasuredrelativetotheP-Qjunction3keymeasurements(P-Qjunction,J-point,60-80msecafterJ-point-use60msecforHR>130bpmWhenJ-pointisdepressedrelativetoP-Qjunctionatbaseline:NetdifferencefromtheJjunctiondeterminestheamountofdeviationWhentheJ-pointiselevatedrelativetoP-Qjunctionatbaselineandbecomesdepressedwithexercise:MagnitudeofSTdepressionisdeterminedfromtheP-QjunctionandnottherestingJpoint第53页/共93页CriteriaforReadingST-SegmentChangesontheExerciseECGSTELEVATION:60msecafterJpointin3consecutiveECGcomplexes第54页/共93页CriteriaforAbnormalandBorderlineST-SegmentDepressionontheExerciseECGABNORMAL:1.0mmorgreaterhorizontalordownslopingSTdepressionat60msecafterJpointon3consecutiveECGcomplexesBORDERLINE:0.5to1.0mmhorizontalordownslopingSTdepressionat60msecafterJpointon3consecutiveECGcomplexes2.0mmorgreaterupslopingSTdepressionat60msecafterJpointon3consecutiveECGcomplexes第55页/共93页MorphologyofST-SegmentDeviation

duringExerciseTesting第56页/共93页ValueofRight-SidedECGLeadsduringExerciseTestingfortheDiagnosisofCAD第57页/共93页HorizontalST-segmentDepressionduringExerciseTesting第58页/共93页DownslopingST-SegmentDepressionduringExerciseTesting第59页/共93页ST-SegmentDepressioninEarlyRecoveryPeriodafterExerciseTesting第60页/共93页UpslopingST-SegmentDepressionduringExerciseTesting第61页/共93页MorphologyofST-SegmentDepressionPredictsSeverityofCoronaryArteryDisease

(Goldschlager,1976)第62页/共93页Exercise-InducedST-SegmentElevationwithPriorAnteriorMyocardialInfarction第63页/共93页Exercise-InducedST-SegmentElevationintheSettingofPriorInferolateralMI第64页/共93页Exercise-InducedAnteriorST-SegmentElevationasReflectionofLADIschemia第65页/共93页Indicationsfor

ExerciseTestingintheDiagnosisofObstructiveCoronaryDiseaseCLASSI:Adultpatients(includingthosewithRBBBorlessthan1mmorrestingST-depression)withanintermediatepretestprobabilityofCAD,basedongender,age,andsymptomsCLASSIIa:PatientswithvasospasticanginaCLASSIIb:PatientswithahighpretestprobabilityofCADbyage,symptoms,andgenderPatientswithalowpretestprobabilityofCADbyage,symptoms,andgenderPatientswithlessthan1mmofbaselineSTdepressionandtakingdigoxinPatientswithECGcriteriaofLVHandlessthan1mmSt-depression第66页/共93页Pre-testProbabilityofCAD

byAge,Gender,andSymptomsTypical/DefiniteAnginaPectorisAge30-39 Men Intermediate(10-90%)Women IntermediateAge40-49 Men High(>90%)Women IntermediateAge50-59 Men HighWomen IntermediateAge60-69Men HighWomen High第67页/共93页Pre-testProbabilityofCAD

byAge,Gender,andSymptomsAtypical/PossibleAnginaPectoris:Age30-39Men Intermediate Women VeryLow(<5%)Age40-49 Men Intermediate Women Low(<10%)Age50-50 Men Intermediate Women IntermediateAge60-69 Men Intermediate Women Intermediate第68页/共93页Pre-testProbabilityofCAD

byAge,Gender,andSymptomsNonanginalChestPain:Age30-39 Men Low Women VeryLowAge40-49 Men Intermediate Women VeryLowAge50-59 Men Intermediate Women LowAge60-69 Men Intermediate Women Intermediate

第69页/共93页Pre-testProbabilityofCAD

byAge,Gender,andSymptomsAsymptomatic:Age30-39Men VeryLow Women VeryLowAge40-49Men Low Women VeryLowAge50-59Men Low Women VeryLowAge60-69Men Low Women Low第70页/共93页Indicationsfor

ExerciseTestingintheDiagnosisofObstructiveCoronaryDiseaseClassIII:PatientswiththefollowingECGabnormalities:WPWsyndrome,electronicallypacedventricularrhythm,greaterthan1mmrestingST-depression,completeLBBBPatientswithadocumentedMIorpriorcoronaryangiographydemonstratingsignificantCADhaveanestablisheddiagnosis(?ischemia,prognosis)第71页/共93页ExerciseTesting;SensitivityandSpecificityfortheDiagnosisofCADSensitivity=[Truepositives/truepositives+falsenegatives]x100Specificity=[Truenegatives/falsepositives+truenegatives]x100StandardExerciseTest(mostlymen)*Sensitivity=68% Specificity=77%PredictiveAccuracy=73%*Basedon1.0mmST-segmentdepression第72页/共93页ExerciseTestingintheDiagnosisofCoronaryArteryDiseaseinWomenECGAnalysisalone:Sensitivity: 46-79%Specificity: 48-86%UseofDukePrognosticScore:LowRiskscore:19.1%CAD>75%stenosis, 3.5%3-vesselorleftmaindiseaseIntermediateRiskscore:34.9%CAD>75%stenosis,12.4%3-vesselorleftmaindiseaseHighRiskScore:89.2%CAD>75%stenosis,46%3-vesselorleftmaindisease第73页/共93页RiskAssessmentandPrognosiswithExerciseTestinginPatientswithSymptomsandPriorHistoryofCADClassI:PatientundergoinginitialevaluationwithsuspectedorknownCADincludingthosewithcompleteRBBBandlessthan1mmofrestingECG(exceptions-ClassIIb)PatientswithsuspectedorknowCADpreviouslyevaluated,nowpresentingwithsignificantchangeinclinicalstatusLow-riskacutecoronarysyndromepatients8-12hoursafterpresentationwhohavebeenfreeofactiveischemiaorheartfailuresymptoms(LevelofEvidence=B)Intermediate-riskacutecoronarysyndromepatients2-3daysafterpresentationwhohavebeenfreeofactiveischemiaorheartfailuresymptoms(LevelofEvidence=B)第74页/共93页RiskAssessmentandPrognosiswithExerciseTestinginPatientswithSymptomsandPriorHistoryofCADClassIIa:Intermediate-riskacutecoronarysyndromepatientswhohaveinitialcardiacmarkersthatarenormal,arepeatECGwithoutsignificantchange,andcardiacmarkers6-12hoursaftertheonsetofsymptomsthatarenormalandnootherevidenceofischemiabyobservation(LevelofEvidence=B)ClassIIb:PatientswiththefollowingECGabnormalities:WPWsyndrome,electronicallypacedventricularrhythm,1mmormoreofrestingST-depression,completeLBBBorIVCDwithaQRSduration>120msecPatientswithastableclinicalcoursewhoundergoperiodicmonitoringtoguidetreatment第75页/共93页RiskAssessmentandPrognosiswithExerciseTestinginPatientswithSymptomsandPriorHistoryofCADClassIII:Patientswithsevereco-morbiditylikelytolimitlifeexpectancyand/orcandidacyforrevascularizationHigh-riskacutecoronarysyndromepatients(LevelofEvidence=c)第76页/共93页Short-termRiskAssessmentforDeathorNonfatalMIinPatientswithAcuteCoronarySyndrome

HIGHRISK(atleastoneofthefollowingfeatures):CharacterofPain: Prolongedongoing(>20min)restchestpainClinicalFeatures:Pulmonaryedema,neworworseningMR,S3ornew/worseningrales,hypotension,bradycardia,tachycardia,age>75yrsECGFindings:AnginaatrestwithtransientSTchanges>0.05mV,BBB(neworpresumednew),sustainedventriculartachycardiaBiochemicalMarkers:Elevatedtroponin-I第77页/共93页Short-termRiskAssessmentforDeathorNonfatalMIinPatientswithAcuteCoronarySyndromeINTERMEDIATERISK:Nohigh-riskfeaturebutmusthaveoneofthefollowing:History:PriorMI,peripheralorcerebrovasculardisease,CABGorprolongedaspirinuseCharacterofPain:Prolonged(>20min)restangina,nowresolved,withmoderatetohighlikelihoodofCADRestangina(<20min)orrelievedbysublingualNTGClinicalFindings:age>70yrsECGFindings:T-waveinversionsgreaterthan0.2mV,pathologicalQ-wavesBiochemicalMarkers:Borderlineelevatedtroponin-I第78页/共93页Short-termRiskAssessmentforDeathorNonfatalMIinPatientswithAcuteCoronarySyndromeLOWRISK:Nohighorintermediateriskfeaturesbutanyofthefollowing:CharacterofPain:

New-onsetorprogressiveCCSCIIIorIVanginainpast2weekswithmoderatetohighlikelihoodofCADECGFindings:

NormalorunchangedECGduringanepisodeofchestdiscomfortBiochemicalMarkers:

Normal第79页/共93页PrognosticFactorsfromExerciseTestingElectrocardiographic:MaximumST-depressionMaximumST-elevationST-depressionslope(morphology)NumberofleadsshowingSTchangesDurationofSTdeviationintorecoveryST/HRindexesExercise-inducedventriculararrhythmiasTimetoonsetofSTdeviation第80页/共93页PrognosticFactorsfromExerciseTestingHemodynamic:MaximumexerciseheartrateMaximumexerciseSBPMaximumexercisedoubleproduct(HRxSBP)Totalexerciseduration(functionalcapacity)ExertionalhypotensionChronotropicincompetenceAbnormalheartraterecovery第81页/共93页HeartRateRecoveryAfterExerciseTestingPredictsOutcomeinCAD

第82页/共93页PrognosticFactorsfromExerciseTestingSymptomatic:Exercise-inducedanginaExercise-inducedsymptoms(SOB,dizziness)Timetoonsetofangina第83页/共93页PrognosticScoreinAssessmentofCardiacEventRiskduringExerciseTestingDukePrognosticScore:TreadmillScore=exercisetimex5(amountofST-segmentdeviation)-4xexerciseanginaindex(0=none,1=presentbutnotlimiting,2=reasontostopthetest)HighRisk:<-11 (5%annualmortality)LowRisk:>+5 (0.5%annualmortality)InformationadditivetocoronaryanatomyandLVEF第84页/共93页DukePrognosticScoreNomogram第85页/共93页CombinedPrognosticFactorsIncreasePredictiveValueofExerciseTestingDatainCAD第86页/共93页IndicationsforExerciseTestingafterMyocardialInfarctionClassI:Beforedischargeforprognosticassessment,activityprescription,evaluationofmedicaltherapy(submaximalversusmaximal,submaximal4-6days)Earlyafterdischargeforprognosticassessment,activityprescription,evaluationofmedicaltherapy,andcardiacrehabilitationifpre-dischargeexercisetestwasnotdone(symptom-limited,about14-21days)Lateafterdischargeforprognosticassessment,activityprescription,evaluationofmedicaltherapy,andcardiacrehabilitationiftheearlyexercisetestwassubmaximal(symptom-limited3-6weeks)第87页/共93页Indi