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★
Result
showedthat
both
oils
contain
alkane,
alcohol,
ester,
ketone,
acid,
phenolandalkene,['estə]酯['fiːnɒl]石碳酸;苯酚andthe
maincomponents主要成分are
tricosane,pentacosane二十五烷and
heptacosane.['traikəsein]二十三烷
[hep'tækəsein]二十七烷
★Aldosteroneisahormonesecretedbytheadrenal
cortex肾上腺皮质thatregulateselectrolyte[ə'driːn(ə)l]
['kɔːteks][ɪ'lektrəlaɪt]电解质andwaterbalancebyincreasingtherenal
['riːn(ə)l]肾(脏)的retention保留,滞留ofsodium
['səʊdɪəm]钠andtheexcretion[ɪk'skriːʃ(ə)n;ek-]
排泄(物);分泌(物)ofpotassium
[pə'tæsɪəm]钾.※-ose糖saccharide糖;糖类
['sækəraɪd]
monose单糖
monosaccharide
[mɒnə(ʊ)'sækəraɪd]
pentose戊糖
['pentəus]
ribose核糖
['raɪbəʊz;-s]deoxyribose脱氧核糖
[dɪ,ɒksɪ'raɪbəʊz;-s]
hexose['heksəus]己糖
glucose葡萄糖
['gluːkəʊs;-z]
fructose果糖
['frʌktəʊz;-s]
diose二糖,双糖
disaccharide[dai'sækəraid]
maltose麦芽糖['mɔːltəʊz;-s;mɒlt-]sucrose蔗糖['s(j)uːkrəʊz;-əʊs]
lactose乳糖['læktəʊz;-s]
cellobiose纤维二糖
[,seləu'baiəuz]
★Allcarbohydrate[kɑːbə'haɪdreɪt]碳水化合物foods,astheyaredigested,eventuallybreakdownintosimplesugars(monose),suchasglucoseandfructose.★Sucroseisadisaccharide(diose)composedofonemolecule['mɒlɪkjuːl]分子ofglucoseandonemoleculeoffructose.★Themostimportantrepresentativesofdisaccharidesaresucrose,lactose,maltoseandcellobiose.★Glucosewithasix-carbon-atomaldehydesugaristermedanaldohexose.2.
transferase转移酶
['trænsf(ə)reɪz;'trɑːns-]methyltransferase,MT甲基转移酶[,meθil'trænsfəreis]◆phenylethanolamine-N-methyltransferase苯乙醇胺phenylethylamine苯乙胺◆T['kætɪtʃɒl;-kɒl]儿茶酚氧位甲基转移酶catecholamine儿茶酚胺[,kætɪ'kəʊləmiːn]transaminase=aminotransferase转氨酶,氨基转移酶[træn'zæmɪneɪz(s)][ə,miːnəʊ'trænsfəreɪs]acetyltransferase乙酰转移酶kinase激酶['kaɪneɪz]
★
Nitric
['naɪtrɪk](含)氮的oxide(NO)
plays
animportant
role
in
cardiovascularsystem.[,kɑːdɪəʊ'væskjʊlə]心血管的
Nitric
oxide
synthase(NOS)is
thekeyenzymeduringthe
synthesis
['sɪnθɪsɪs]合成process
ofNO.
★Maltasecancatalyzethehydrolysisofmaltose
['kætəlaɪz]催化[haɪ'drɒlɪsɪs]水解作用
totwo
glucoses.
★
Amylase
and
lipase
valuestypically
willbe
elevated
in
the
early
or
acute
stage
ofpancreatitis.pancreas
['pæŋkrɪəs]胰腺[,pæŋkrɪə'taɪtɪs]胰腺炎
★The
salicylate
hydroxylasecan
catalyze
the
[sə'lɪsɪlət]水杨酸[hai'drɔksileis]羟化酶
decarboxylationandhydroxylationof
salicylate
to
[‘diːkɑː,bɒksɪ’leɪʃən]脱羧
[haidrɔksi‘leiʃən]
羟基化
form
catechol.★
Lowtemperature
reducedthe
activities
ofthe
enzymes
related
to
fiber
synthesis,includingphenylalaninedeaminase,polyphenol
oxidase,
[,fiːnaɪl'æləniːn;fenɪl-]
苯(基)丙氨酸[di'æmineis]脱氨(基)酶cinnamyl
alcoholdehydrogenase肉桂醇脱氢酶and
[si'næmil]
肉桂基
cinnamon['sɪnəmən]肉桂
peroxidase[pə'rɒksɪdeɪz]过氧化物酶.
★Someimportantcatecholamines儿茶酚胺类
suchas
epinephrine,norepinephrine
anddopamine[,epɪ'nefrɪ(ː)n]肾上腺素,[,nɔːrepɪ'nefrɪ(ː)n]去甲肾上腺素
canbemetabolized[mɪ'tæbəlaɪz]代谢
bycatechol-O-methyltransferase(COMT)andmonoamineoxidase(MAO).
★Acetylcholineisakindofneurotransmitters.[,njʊərəʊtrænz'mɪtə]
神经递质Itissynthesizedinthecytoplasmfrom['sɪnθəsaɪz]合成['saɪtə(ʊ)plæz(ə)m]
细胞质
acetyl-CoAandcholinethroughthecatalyticaction胆碱
[,kætə'lɪtɪk]起催化作用的
oftheenzyme-cholineacetyltransferase(ChAT).
胆碱乙酰转移酶Acetyl-CoAissynthesizedinmitochondriawhich
[,maɪtəʊ'kɒndrɪə]线粒体,
arepresentinlargenumbersinthenerveending.Acetylcholinesterase(AChE)isanenzymethatcatalyzesthehydrolysisofacetylcholinetocholineandacetate.Aspirin
(acetylsalicylicacid;ASA)◆Clinicaluses临床应用:Analgesia镇痛,Antipyresis解热,andAnti-inflammatory抗炎Effects
analgesia
[,æn(ə)l'dʒiːzɪə]n.痛觉缺失
algesia
[æl'dʒi:ziə,-siə]痛觉,感觉过敏
anti-inflammatoryadj.抗炎的n.抗炎药inflammatory[ɪn'flæmət(ə)rɪ]adj.炎症性的
★Aspirinisemployedformildtomoderatepainofvariedoriginbutisnoteffectiveforsevere
visceral['vɪs(ə)r(ə)l]内脏的
pain.
AspirinandotherNSAIDs(NonsteroidalAnti-inflammatoryDrugs非甾体抗炎药)
nonsteroidal[,nɔnstə'rɔidəl]非甾类化合物的,非类固醇的steroid
['stɪərɒɪd;'sterɒɪd]类固醇;甾族化合物havebeencombinedwithopioidanalgesics
opioid['əʊpɪɒɪd]类鸦片,阿片样物质,阿片类
analgesic[,æn(ə)l'dʒiːzɪk;-sɪk]镇痛药
fortreatmentofcancerpain,wheretheiranti-inflammatoryeffectsactsynergistically协同地
synergistic[,sɪnə'dʒɪstɪk]adj.协同的,协作的,协同作用withtheopioidstoenhanceanalgesia镇痛.High-dosesalicylateareeffectivefortreatmentofrheumaticfever风湿热,
rheumatoid类风湿性
arthritis
andotherinflammatoryjoint关节
conditions.rheumatic[rʊ'mætɪk]
风湿病(患者);风湿病的,风湿病引起的rheumatoid['ruːmətɒɪd]
患风湿症的,类风湿性的arthritis[ɑː'θraɪtɪs]关节炎B.OtherEffects★Aspirindecreasestheincidence
发病率oftransientischemicattacks短暂性脑缺血发作,unstableangina不稳定型心绞痛,coronaryarterythrombosis冠状动脉血栓形成withmyocardialinfarction心肌梗死,心肌梗塞,andthrombosisaftercoronaryarterybypassgrafting冠状动脉旁路移植术.Epidemiologicstudies流行病学研究
suggestthatlong-termuseofaspirinatlowdosageisassociatedwithalowerincidenceofcoloncancer结肠癌,possiblyrelatedtoitscyclooxygenase(COX)-inhibitingeffects.
★
Sodiumnitroprussideisapowerfulparenterally(parenteral
[pə'rent(ə)r(ə)l]肠胃外的,不经肠道的,注射用药物的)
administeredvasodilatorthatisusedintreating给药[,veɪzəʊ'daɪleɪtə]血管舒张药hypertensiveemergencies高血压急症aswellassevereheartfailure.★
Nitroprussidedilatesbotharterialandvenous
[daɪ'leɪt]使扩大动脉的['viːnəs]静脉的vessels,resultinginreducedperipheralvascularresistance外周血管阻力andvenousreturn.Theactionoccursasaresultofactivationofguanylylcyclase鸟苷酸环化酶,eitherviareleaseofnitricoxideorbydirectstimulationoftheenzyme.bisulfate硫酸氢盐◆ammoniumbisulfateNH4HSO4sulfite亚硫酸盐◆sodium,potassium+sulfite
bisulfite亚硫酸氢盐
◆potassiumbisulfiteKHSO3
sulfide硫化物
◆hydrogensulfide
H2S
★
Thereare
six
common
airpollutants:
ozone
['əʊzəʊn]臭氧,
nitrogen
dioxide,carbonmonoxide,
lead铅,
sulfur
dioxide
and
particulatematter粉尘.
★Hydrogen
sulfide
is
a
molecule
consisting
of
twohydrogen
atoms
and
onesulfur
atom.
★
Pharmacologyisanimportantsubjectstudyingtheinteractionsthatoccurbetweenalivingorganismandsomechemicalsandtheeffectsofthosechemicalsonthenormalandabnormalbiochemicalfunctionsoftheorganism.Thetwomainareasofpharmacologyarepharmacodynamicsandpharmacokinetics.Pharmacologyisanexperimentaldiscipline,whichdealswith
howdrugsinteractwithinbiologicalsystemsbyperformingexperimentalstudiesinvitro
[in'vi:trəu,-'vi-]在体外,在试管内,exvivo间接体内法,体外andinvivo
[in'vi:vəu,-'vai-]在体内.
★Pharmacologyresearchisdividedintopre-clinicalandclinicaltrials.Theformerinvolvesinvitro(testtubeorcellculture)andinvivo(animal)experiments,whichproducecriticalpreliminaryresults.Theseresultsformthebasisforevaluationofdrugcandidatesandtheirpotentialforfurtherdevelopmentintonewdrugs.Thelatteristheclinicaltestingofdrugcandidatesinhumansubjects,thiswillnormallyproceedthroughfourphasesofclinicalstudies.★Drugdevelopmentsconsiderationsarefirst,thesafetyofthedrugs;second,theeffectivenessoftreatmentsandthird,thehighselectivityofdrugs.Intheprocessofdrugdevelopments,pharmacologyplaysacrucialroleintargetdiscoveryandevaluation,drugmechanismelucidation阐明,drugstructuraloptimization,targetproteinrecognition,drugsynergism['sɪnədʒɪzəm]协同作用andtoxicitiesassessment.Pharmacokinetics(PK)★
Pharmacokinetics(PK)includestwointerrelatedprocesses.Thefirstprocessisdrugabsorption,distribution,metabolism
(biotransformation)andexcretion(ADME),andanotheristheevaluationofthequantitativekineticprocessesofADMEbykineticprinciplesandmathematicalmodels.★Absorptionisthepassageofthedrugfromitssiteofadministration给药intotheblood.Besidesgastrointestinal
[,gæstrəʊɪn'testɪn(ə)l]tract胃肠道thereareseveralotherroutesforabsorptionsuchasintramuscular[,ɪntrə'mʌskjʊlə]肌肉内的
orsubcutaneous[,sʌbkjuː'teɪnɪəs]皮下的
adminstration,andattimes,throughlungorskin,etc.Distributionisthedeliveryofdrugtothetissue.Toreachitssiteofaction,adrugmustcrossanumberofbiologicalbarriers(blood-brainbarrier,placental
[plə'sɛntl]barrier胎盘屏障,etc)andthepredominantlylipid['lɪpɪd]membranes脂质膜.Bothmetabolismandexcretioncanbeviewedasprocessesresponsibleforeliminationofdrug(parentandmetabolite
[mɪ'tæbəlaɪt]代谢物)fromthebody.Drugmetabolismchangesthechemicalstructureofadrug,thisaltereddrugproductiscalledadrugmetabolite,whichisfrequentlybutnotuniversallylesspharmacologicallyactive.Metabolismalsorendersthedrugcompoundmorewatersolubleandthereforemoreeasilyexcreted.TheADMEprocessesofadruginvolveitspassageacrossacellmembrane.Thephysicalandchemicalpropertiesofthedrugmoleculesandthecellmembranesthataffectthistransferarethuscriticalinunderstandingthedisposition
[dɪspə'zɪʃ(ə)n]处置ofdrugsinthehumanbody.
Therearetwowaysthatdrugmoleculespassthroughthemembrane:eitherbypassiveprocessesorbymechanismsinvolvingtheactive
participaitonofcomponentsofthemembrane.★Mathematicalmodelsareoftenusedtodescribethekinetics[kɪ'netɪks;kaɪ-]动力学ofdrugelimination.Thesemainlyincludefirstorderkinetics,zeroorderkineticsandMichaelis-MentenkineticswithimportantPK
parameters参数[pə'ræmɪtə(r)z]suchast1/2,Vd,AUC,F,CLtot,Cssetc.
t1/2:half-lifeF:bioavailability[,baɪəʊə,veɪlə'bɪlɪti]生物利用度
Vd:apparentvolumeofdistribution
AUC:areaundertheconcentration-timecurveCLtot:totalbodyclearance
Css:steady-stateplasmaconcentrationPhaseⅠandphaseⅡMetabolism★DrugbiotransformationreactionsareclassifiedaseitherphaseⅠfunctionalization[,fʌŋkʃənəlai'zeiʃən]
功能化(oxidation氧化,reduction还原
andhydrolysis)reactionsorphaseⅡbiosynthetic[,baiəusin'θetik]
生物合成的(conjugation[kɒndʒʊ'geɪʃ(ə)n]接合)reactions.PhaseⅠreactionsintroduceafunctionalgroup
官能团ontheparentcompound.PhaseⅠreactionsgenerallyresultinthelossofpharmacological
activity药理活性,althoughthereareexamplesofretentionorenhancementofactivity.Inrareinstances,metabolismisassociatedwithanaltered['ɔːltəd]改变了的pharmacologicalactivity.
Prodrugs前药arepharmacologicallyinactivecompounds,designedto旨在,目的在于maximize['mæksɪmaɪz]最大化theamountoftheactivespeciesthatreachesitssiteofaction.Inactiveprodrugsareconvertedrapidlytobiologicallyactivemetabolites,oftenbythehydrolysisofanesteroramide
['eɪmaɪd;'æmaɪd]linkage连接
['lɪŋkɪdʒ]酰胺键.Ifnotrapidlyexcretedintotheurine['jʊərɪn;-raɪn]
尿,theproductsofphaseⅠbiotransformationreactionscanthenreactwithendogenous[en'dɒdʒɪnəs;ɪn-]内源的,内生的compoundstoformahighlywatersoluble水溶性的conjugate
['kɒndʒʊgeɪt].
★PhaseⅡconjugationreactionsleadtotheformationofacovalentlinkagebetweenafunctionalgroupontheparentcompoundorphaseⅠmetabolitewithendogenously内生地derivedglucuronicacid葡萄糖醛酸,sulfate,glutathione[,gluːtə'θaɪəʊn]谷胱甘肽,aminoacids,oracetate.Thesehighlypolarconjugatesaregenerallyinactiveandareexcretedrapidlyintheurineandfeces['fiːsiːz]粪便.Anexampleofanactiveconjugateisthe6-glucuronide葡糖苷酸[ɡlu:'kjuərənaid]metaboliteofmorphine吗啡['mɔːfiːn],whichisamorepotent更强
analgesic
[,æn(ə)l'dʒiːzɪk;-sɪk]镇痛药thanitsparentcompound.
Thelipids['lipidz]脂类ofhumanplasma血浆['plæzmə]
aretransportedinmacromolecular[,mækrəuməu‘lekjulə]大分子的complexes复合物termedlipoproteins.Anumberofmetabolic
代谢的
[,metə'bɒlɪk]disordersthatinvolveelevationsinlevelsofanyofthelipoproteinspeciesarethustermedhyperlipoproteinemiasorhyperlipidemias.Thetermhyperlipemiadenotesincreasedlevelsof
triglycerides[traɪ'ɡlɪsə,raɪd]甘油三脂inplasma.
CompetitiveinhibitorsofHMG-CoAreductase(reductase-inhibitors;“statins”他汀类药物
)
Thesecompoundsarestructuralanalogs类似物
ofHMG-CoA.Lovastatin['ləuvə,stætin]洛伐他汀,atorvastatin[ə,tɔrvə'stætin]阿托伐他汀,fluvastatin氟-,pravastatin普-,simvastatin辛-,
androsuvastatin瑞舒-belongtothisclass.TheyaremosteffectiveinreducingLDL.Ithasestandardpracticetoinitiatereductaseinhibitortherapyimmediatelyaftermyocardialinfarction,irrespectiveoflipidlevels.Reductaseinhibitorsareusefulaloneorwithresins,niacin
['naɪəsɪn]烟酸,orezetimibe
依折麦布inreducinglevelsofLDL.Becausecholesterolbiosynthesisoccurspredominantlyatnight,reductaseinhibitors-exceptatorvastatinandrosuvastatin-shouldbegivenintheeveningifasingledailydoseisused.Absorptiongenerally(withtheexceptionofpravastatin)isenhancedbytakingthedosewithfood.※
dys-不良,困难,异常,障碍
dystrophy营养障碍,营养不良['distrəfi]dysfunction
机能不良,机能障碍[dis'fʌŋkʃən]dyslipoproteinemia
血脂蛋白异常
dysglycemia
血糖代谢障碍[disɡlai'si:miə]dyspnea呼吸困难[disp'ni:ə]dyspepsia[dis'pepsiə]
消化不良poordigestiondyskinesia运动障碍[,dɪskaɪ'niːzɪə][,dɪskɪ'niʒə]dystonia肌张力障碍[dɪs'təʊnɪə]◆tardivedyskinesia迟发性运动障碍
['tɑ:div]迟缓的,迟发的★Lecithin
[‘lesɪθɪn]卵磷脂may
prove
useful
in
alleviating
减轻the
symptoms
of
Senile
dementia老年痴呆症,[‘siːnaɪl]
高龄(所致)的,老衰的[dɪ'menʃə]痴呆Alzheimer‘s
['ælz'ɛmɚ]disease
阿尔茨海默氏症and
Tardive
dyskinesia.
★Dyslipoproteinemia
is
correlated
with
the
occurrence
and
development
ofatherosclerosis
[,æθərəʊsklɪə‘rəʊsɪs;-sklə-]
动脉粥样硬化,动脉硬化and
cardiocerebralvascular
diseases.
★Islet
['aɪlɪt]胰岛transplantation移植
hasalreadybeen
able
to
maintain
long-term
euglycemiaand
noninsulin['ɪnsjʊlɪn]胰岛素-dependence
inpatientswith
Type
1
Diabetes[,daɪə'biːtiːz]糖尿病.
★TheFDA
hasalready
approved
DBS
asa
treatmentfor
neurologic[,njuərə'lɔdʒikəl]
disorders神经系统疾病,
includingessentialtremor原发性震颤,
Parkinson‘s
disease['pa:kinsnzdizi:z]帕金森症,
dystonia,
and
severe
pulsivedisorder.※
-genesis起源,发生,形成
pathogenesis[,pæθə'dʒenisis]发病,致病,发病机制carcinogenesis[,kɑ:sinəu'dʒenisis]致癌作用,癌发生teratogenesis[,terətəu'dʒenisis]畸形发生,致畸作用mutagenesis[,mju:tə'dʒenisis]诱变,突变发生atherogenesis[,æθərəu'dʒenisis]动脉粥样化形成atherosclerosis动脉粥样硬化
lithogenesis[,liθə'dʒenisis]结石形成
★Thedisorderoflipid脂类metabolismismajorpathogenesisoffattyliver.★Safeuse:notproduceanyorganicchlorideandotherharmfulsubstancesthatmayleadtocarcinogenesis,teratogenesisandmutagenesis,suchastrihalomethane三卤甲烷
andchloroform.※
abdomin/o-腹abdomen,belly,stomachabdominal腹部的
[æb'dɒmɪn(ə)l]endoabdominal[,endəu'æbdɔminl]腹内的abdominalgia腹痛abdominoscopy腹腔镜检查(法)※
lapar/o-腹laparotome剖腹刀laparotomy剖腹术
[,læpə'rɒtəmɪ]
laparoscope腹腔镜['læpərəuskəup]
laparoscopy腹腔镜检查[læpə'rɔskəpi]★Abdominoscopy---yourdoctorviewsyourabdominalcavitybymakingtinyincisionsinyourabdomen[æb'dəumen;'æbdəmen]
andinsertingafiber-optic纤维光学tubewithasmallcameralens.adrenoceptor肾上腺受体
●Adrenoceptoragonists
adrenomimetics
拟肾上腺素药
●Adrenoceptorantagonists★Adrenoceptoragonists(andantagonists)areclassifiedintothreetypes:α-
adrenoceptor
agonists(andantagonists),α,β-agonists(andantagonists)andβ-agonists(andantagonists).Theβ-antagonistshavewidespreadandimportantusesinthemanagementofcardiacarrhythmias心律失常,angina
[æn'dʒaɪnə]pectoris心绞痛,andhypertension.★Happinessisconnectedtotwokeymoodregulatorsthatourbrainsproduceserotonin
[,serə'təʊnɪn]血清素,5-羟色胺(血管收缩素)andnoradrenaline.※
andr/o-雄
※
estr/o-雌androgen雄(性)激素(-gen致…物)['ændrədʒ(ə)n]malehormone---
testosterone
[te'stɔstərəun]睾酮estrogen雌(性)激素['estrədʒən]
femalehormoneestradiol雌二醇[,estrə'daiəl]estriol雌三醇['e:striɔl]estrone雌酮['estrəun]★Naturalestrogensinclude
estradiol,estriolandestrone.Theestradiolproducesthemostactivelybiologicalfunction,subsequentisestriol,andthelastisestrone.★Theeffectsofestrogensaremediatedby
estrogenreceptor.※
ather/o粥样沉积,动脉粥样化atherogenesis动脉粥样化形成atherogenic致动脉粥样化的atherosclerosis,AS动脉粥样硬化●coronaryatherosclerosis●aortaatherosclerosis●
carotid
atherosclerosis
[kə'rɒtɪd]n.颈动脉adj.颈动脉的●
femoralatherosclerosis
['fɛmərəl]adj.股骨的;大腿的;大腿骨的antiatherosclerosis抗动脉粥样硬化●
antiatherosclerosisfactor–HDL
★Lack
of
physical
activity
may
increase
LDL,or
bad
cholesterol,and
decrease
HDL,orgoodcholesterol.
※
spir/o
螺旋spiral螺旋;螺旋形的['spaɪr(ə)l]spiramycin螺旋霉素[,spaiərə'maisin]acetylspiramycin乙酰螺旋霉素spirillum螺旋菌
[spaɪ'rɪləm]spirilla(pl)spirochete螺旋体['spaɪərəʊkiːt]
spirochetemia,spirocheticidal,spirocheticidespirochetolysis,spirochetolysin,spirochetosis
★
Endotoxinisakindoflipopolysaccharideinthecellwalllayerofgramnegativebacteriumandothermicroorganismincludingchlamydia衣原体[klə'mɪdɪə],rickettsia立克次体[rɪ'ketsɪə],spirocheteorsomethingelse.WhentheydiedorpropagatedactivelyamountofEndotoxinwillbereleased.※denti-牙※odont-牙toothdentofacial牙面的dentist牙医dentosurgical牙外科的
[,dentəu'sə:dʒikəl]odontolith牙垢,牙积石periodontitis牙周炎[,periədɔn'taitis]dentiform,dentoid,odontoid齿状的odontology,dentologyodontopathyodontalgia,dentalgiaodontoneuralgia※gingiv/o-龈gumgingivostomatitis龈口炎[,dʒindʒivəu,stəumə'taitis]gingivitisgingivalgiagingivectomy★Elderlypatientswithdiabetes[,daɪə'biːtiːz]糖尿病areoftenpaniedbyvaryingdegrees不同程度ofgingivitisandperiodontitis.※
bronch-,bronchi-支气管
bronchus['brɒŋkəs]支气管(pl)bronchi['brɒŋkaɪ]bronchitis支气管炎[,brɔŋ'kaitis]bronchiospasm支气管痉挛※
trache/o-气管
trachea气管;导管[trə'kiːə;'treɪkɪə]tracheal
气管的;导管的[trə'kiːəl]
endotracheal[,endəutrə‘ki(:)əl]气管内的
tracheitis
气管炎[,treɪkɪ'aɪtɪs]
tracheobronchitis气管支气管炎[,treikiəubrɔŋ'kaitis]★
Tracheitis:
Inflammation
and
infection
ofthe
trachea.
※
pulm/o-,pulmon/o-肺※
pneumon/o-肺pulmonohepatic肺肝的pulmoaortic肺与主动脉的aorta主动脉
pneumonorrhagia肺出血pneumonitis;pulmonitis,pneumonia肺炎
●bacterialpneumonia[njuː'məʊnɪə]
细菌性肺炎
pneumococcuspneumococcidepneumococcidalpneumococcemiapneumococcolysis
★
Pneumococcus
is
theleadingcauseof
pneumonia.★The
most
common
complications
of
flu
arebronchitis
and
secondary
bacterialpneumonia.※
salping-,tub-管,输卵管
oviduct['əʊvɪdʌkt]
salpingectomy,tubectomy输卵管切除术[,sælpɪn'dʒektəmɪ]
salpingo-oophorectomy[,əʊəfə'rektəmɪ]
salpingo-ovariectomy[,əʊvərɪ'ektəmɪ]
输卵管卵巢切除术
salpingitis[,sælpɪn'dʒaɪtɪs]
输卵管炎
★
Gynecological[,ɡaɪnɪkə'lɒdʒɪkəl]妇科的inflammation,suchasvaginitis[,vædʒɪ‘naɪtɪs]阴道炎,
cervicitis[,sɜːvɪ‘saɪtɪs]宫颈炎couldinfectoviduct,causesalpingitis.★Objective:Toexploretheclinicalvalueofgynecologicallaparoscopic[,læpərə'skɒpɪk]
surgery腹腔镜手术onhysteromyoma[histərəmai'əumə]子宫肌瘤.
lactate[læk'teɪt]
vi.分泌乳汁,喂奶n.乳酸盐sodiumlactatelactic乳的,乳汁的lacticacidprolactin,PRL催乳(激)素[prəʊ'læktɪn]●prolactin-releasinghormone,PRH★Hormoneimbalances,suchastestosterone
[te'stɒstərəʊn]睾酮,睾丸素deficiencyortoomuchoftheprolactin,cancauseerectile[ɪ'rektaɪl]
dysfunction,ED
勃起功能障碍.★
Papaya[pə'paɪə]木瓜isgalactagogue
containingphytoestrogens植物雌激素,andasmallamountofnaturalprogesterone[prə'dʒestərəʊn]黄体酮.sterone['stiərəun]甾酮,固酮aldosterone醛固酮menorrhea行经,月经,月经过多hypermenorrhea,menorrhagia,menometrorrhagiamenalgia痛经painfulmenstruationdysmenorrhea痛经;月经困难[,dɪsmenə'rɪə]★Afterage60osteoporosisesmuchmorecommon,particularlyforwomenwhohavegonethroughthemenopause.★Menstrualdisordersincludedysmenorrheaandamenorrhea,anduterinebleeding.★Asthenia[əs'θiːnɪə]无力;衰弱cold虚寒caninducemanykindsofmenopathysuchashypomenorrhea,delayedmenorrhea,menostasis,menalgia,andsoon.★Three
main
problemscanoccurinthe
prostate
gland:
inflammation
or
infection,called
prostatitis;
enlargement,
called
benign[bɪ'naɪn]良性的prostatic
hyperplasia(BPH);
andprostatecancer.
★Prostaglandin
E1(PGE1)
is
an
important
endogenous
[en'dɒdʒɪnəs;ɪn-]内源性的
substance
withmanyphysiological
andpharmacological
actionsand
has
widelyappliedinclinicalpractice.★Prostacyclin(PGI2),thromboxane
[θrɔm'bɔksein]血栓素antagonist,isapowerfulvasodilator血管舒张药
andinhibitsplatelet['pleɪtlɪt]
aggregation
[,æɡrɪ'ɡeɪʃən]
血小板聚集,soitcanpreventthethrombosis
[θrɒm'bəʊsɪs]血栓形成.antithyroid抗甲腺的(药)['ænti'θairɔid]
euthyroid甲状腺机能正常的[ju:'θairɔid]
hypoparathyroidism
甲状旁腺功能减退['haipəu,pærə'θairɔidizəm]
hypothyroidism甲状腺功能减退
[,haɪpəʊ'θaɪrɒɪdɪz(ə)m]hyperthyroidism甲状腺机能亢进[,haɪpə'θaɪrɒɪdɪz(ə)m]thyrotoxicosis
甲状腺功能亢进;甲状腺毒症[,θaɪrəʊ,tɒksɪ'kəʊsɪs]
★
Congenital
hypothyroidism
(CH)
先天性甲状腺功能减退症is
the
most
prevalent
endocrine
disorder内分泌紊乱性疾病inthe
newborn
and
isroutinely
treatedwith
life-long
levothyroxine
replacementtherapy
替代疗法.★
Thyroidstimulating
hormone(thyrotropin)
releasing
hormone
(TRH)
stimulates
theanteriorpituitary[pɪ‘tjuːɪt(ə)rɪ]垂体前叶to
liberate
the
thyroid-stimulating
hormone(TSH)
and
prolactin[prəʊ'læktɪn]
催乳素.
★Adjuncts['ædʒʌŋkts]
toantithyroidtherapyDuringtheacutephase[feɪz]
ofthyrotoxicosis(hyperthyroidism),β-adrenoceptor-blockingagentswithoutintrinsic
sympathomimeticactivity[,sɪmpəθəʊmɪ'metɪk]拟交感的areextremelyhelpful.Propranolol
普萘洛尔,心得安[prəʊ'prænəlɒl]20-40mgorallyevery6hours,willcontroltachycardia[,tækɪ'kɑːdɪə],hypertension,andatrialfibrillation
心房纤颤;房颤;心房纤维颤动
.Propranololisgraduallywithdrawn撤退
asserum['sɪərəm]血清thyroxinelevelsreturntonormal.Diltiazem地尔硫卓,90-120mgthreeorfourtimesdaily,canbeusedtocontroltachycardiainpatientsinwhomβ-blockersarecontraindicated,eg,thosewithasthma['æsmə].Othercalciumchannelblockersmaynotbeaseffectiveasdiltiazem.Adequatenutritionandvitaminsupplements维生素添加剂areessential.Barbiturates[ba:'bitjuəreits]
巴比妥类药物accelerateT4breakdown(byhepaticenzymeinduction肝药酶诱导)andmaybehelpfulbothassedatives['sɛdətivz]
镇静剂andtolowerT4levels.★Yogurt
['jɒgət;'jəʊ-]酸奶supplies
the
brainwith
tyrosine['taɪrəsiːn]
酪氨酸,
an
aminoacid
thatboosts
blood
levelsofthe
neurotransmitters
dopamine
and
norepinephrine,
resulting
inamood
andmental
boost.
★Constant
worrying
causes
cortisol
['kɔːtɪsɒl]皮质醇and
epinephrine[,epɪ'nefrɪn;-riːn]
肾上腺素levelstorise-and
these
stresshormones应激激素,压力激素can
weaken
the
body’s
overall
immunity
免疫力[ɪ'mjuːnɪtɪ].
★
Thedrug
may
cause
histamine
release,
whichmaycause
cutaneous
flushing
皮肤潮红
andeven
bronchospasm
and
hypotension
in
some
patients.※
-lemma膜
oolemma卵膜
[,əuə'lemə]basilemma基底膜neurolemma神经膜※
mening/o-脑膜,脊膜meningococcus脑膜炎双球菌
intermeningeal脑脊膜间的
[,intəmi'nindʒiəl]meningomalacia脑膜软化meningoencephalomyelitis脑膜脑脊髓炎
meningitis脑(脊)膜炎
[,menɪn'dʒaɪtɪs]
meningomyelitis脊膜脊髓炎['meniŋɡəu,maiə'laitis]meningocerebritis,meningoencephalitismeningocephalitis脑膜脑炎★Enterovirusinfectionscancausemyocarditis,pneumonia,meningoencephalitis,orevenleadtodeath.★Allofβ-lactam,glycopeptidesandfosfomycin
playtheirbactericidaleffectviainhibitionofsynthesisofcellwall.★
Penicillins[penɪ'sɪlɪn]青霉素,cephalosporins,monolactams(aztreonam氨曲南),carbapenems碳青霉烯类(imi亚胺,mero美罗,pani帕尼,faro法罗,bia比阿,eta厄他+-penem-培南),
cephamycins头霉素类(
Cefoxitin[si'fɔksitin]头孢西丁,Cefmetazole头孢美唑,Cefotetan头孢替坦),andoxacephems氧头孢烯类(latamoxef拉氧头孢)areclassifiedasβ-lactamdrugsbecauseoftheiruniquelactamring.Theyinhibitbacterialgrowthbyinhibitingtranspeptidase[træns'pɛptɪdez]转肽酶
activityinbacterialcellwallsynthesis.★Penicillinisactiveagainstnearlyallstaphylococciandgram-positive
bacilli杆菌.Semisynthesized半合成
Penicillinsarenotonlyagainstgram-positiveorganismsbutgram-negativeorganisms.Thepenicillinsaremarkablynontoxic,b
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