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CELLSStructureandFunctionCell=smallestunitoflifeCELLSStructureandFunction1FeaturesoftheHumanCell

ActinfilamentsNuclearEnvelopeCytoplasmIntermediatefilamentsMicrotubulesVesicleChromatinCentriolesCentrosomeLysosomeGolgiapparatusPolyribosomeMitochondrionRibosomesSmoothERRoughERNucleolusNucleusCytoskeletonEndoplasmic

ReticulumFeaturesoftheHumanCellAct2OrganizationoftheCellPlasmaMembrane

boundarysurroundingthecellGeneticmaterial:DNAlocatedinamembrane-boundnucleus

foreukaryoticcellsCytoplasmSemi-fluidmatrixcontainingenzymes

andorganelles

(enzyme=biologicalcatalyst)Cytoskeletonnetworkoffilamentsandtubulesincytoplasmthatmaintainscellshape,allowsmovementOrganizationoftheCellPlasm3FunctionsofCellFeatures

StructureFunction(s)PlasmaMembrane1.Regulatespassageofmaterialsintoandoutofcell2.Cell-CellRecognitionFunctionsofCellFeaturesSt4FunctionsofCellFeatures

StructureFunction(s)NucleusCarrierofgeneticmaterialDNA+protein=chromatin2.Governscellactivities3.DirectscellreproductionSurroundedbyMembrane=nuclearenvelopeContainsnucleolus—producesribosomesFunctionsofCellFeaturesSt5FunctionsofCellFeatures

StructureFunction(s)RibosomesSiteofproteinsynthesisCanbefreeincytoplasmorattachedtomembranesFunctionsofCellFeaturesSt6FunctionsofCellFeatures

StructureFunction(s)RoughEndoplasmicReticulum(RER)ProducesproteinsPreparesproteinsforexportSmoothEndoplasmicReticulum(SER)LipidSynthesisDrugdetoxificationTransportofproteinsfromRERRERSERFunctionsofCellFeaturesSt7FunctionsofCellFeaturesStructureFunction(s)GolgiApparatusCollects,modifies,packagesanddistributesproteinsandlipidsfromERFunctionsofCellFeaturesStr8FunctionsofCellFeatures

StructureFunction(s)LysosomeContainsdigestiveenzymestodigestfoodinprotistsordestroyagingorganellesFunctionsofCellFeaturesStr9EndomembraneSystemRough

Endoplasmic

ReticulumSmooth

Endoplasmic

ReticulumVesicleGolgi

ApparatusVesicleLysosomeVesiclePlasmaMembraneEndomembraneSystemRough

Endo10FunctionsofCellFeatures

StructureFunctionPeroxisomeRemovesharmfuloxidantsfromcellsFunctionsofCellFeaturesSt11FunctionsofCellFeatures

StructureFunctionMitochondrionCapturesenergyfromorganicmolecules,producingATPFunctionsofCellFeaturesSt12Functionsof

CellFeatures

StructureFunction(s)CytoskeletonMaintainscellshapeAnchorsorganellesandproteinsAllowsfororganellemovement

andcellularmovementinsomecelltypesFunctionsof

CellFeaturesS13FunctionsofCellFeaturesStructureFunctionCentrioleGivesrisetobasalbodiesthatproduceciliaorflagellaFunctionsofCellFeaturesStru14FunctionsofCellFeaturesStructureFunctionCentrosomeOrganizesmicrotubulesthatattachtochromosomesinnucleardivisionFunctionsofCellFeaturesStru15FunctionsofCellFeatures

StructureFunction(s)CiliaandFlagellaMovesubstancesacrosscellsurfaceinlungs,fallopiantubes

CellmovementinspermFunctionsofCellFeaturesSt16ConnectionsBetweenCells

TightJunction:joiningofproteins

createsimpermeablebarrierGapJunction:adjacentchannels

allowcommunicationAdhesionJunction:filamentsofcytoskeletonconnectcells,allowstretchConnectionsBetweenCellsTigh17FunctionsofPlasmaMembraneComponentsOutsideInsideplasmamembraneproteinsfilamentsofcytoskeletoncholesterolcarbohydratechainhydrophobictailsphopspholipidbilayerhydrophilicheadsRegulatesfluidityTransport,signalreception,recognitionCell-cellrecognitionControls

accessFunctionsofPlasmaMembraneC18Diffusion:MovementfromfromhighlowconcentrationtoreachequaldistributionmacromoleculeH2Oaquaporinproteinchargedmoleculesandionsunchargedmoleculesphospholipidmolecule+--+Freelydiffusethrough

phospholipidbilayerDiffusesthroughpores

inmembraneproteinsDiffusion:Movementfromfrom19Osmosis:DiffusionofWaterAcrossaSelectivelyPermeableMembraneIsotonicsolution

maintainscell

shapeCellsgainwaterina

Hypotonic(lowersalt)

solutionCellslosewaterina

Hypertonic(highersalt)solutionMembraneispermeabletowateronly,netmovementofwatertoinsideEqualmovementintoandoutofcellwhenequilibriumisreachedOsmosis:DiffusionofWaterAc20FacilitatedTransport:

UseofCarrierstoAssistwithDiffusionOutsideK+Na+Na+Insideglucosecarrier

proteinFacilitatedTransport:

Useof21ActiveTransportwithProteinCarrier:RequiresenergytotransportfromlowhighconcentrationInsideOutsideK+K+K+K+K+PNa+Na+Na+Na+Na+Na+Na+ATPADPActiveTransportwithProtein22TransportingLargeSubstancesEndocytosisExocytosisvesiclevesicleFormationofavesiclefromtheplasmamembranetotakeinlargesubstancesFusionofavesiclewiththeplasmamembranetoreleaselargesubstancesTransportingLargeSubstancesE23SummaryofTransportMechanismsPassive:DonotrequireenergyinputDiffusionOsmosisFacilitatedTransportActive:RequireenergyinputActiveTransportEndocytosisExocytosisSummaryofTransportMechanism24CellularRespiration:

ProducingATPfromGlucoseGlycolysisglucoseglucosemitochondrionoxygenpyruvate2322ATPInsidecellOutsidecellelectronstransferredbyNADHelectronstransferredbyNADHCitricacidcycleElectronTransportchainATPATPRequiresOxygenEnergyYieldfromGlucoseCellularRespiration:

Produci25WithoutOxygen,FermentationOccurswhenoxygenis

availablecytoplasmNeededtocontinueglucosebreakdownforenergyTrainingreduces

FermentationElectroncarrierproducedinglycolysislactatefermentationNAD+fermentationWithoutOxygen,FermentationO26Enzymes:BiologicalCatalystsThatSpeeduptheRatesofMetabolicReactionsSubstrateSubstrateEnzymeActive

Site1 Substratesenteractivesite2 ShapechangepromotesreactionProductreleased;

enzymereadyagainEnzymes:BiologicalCatalysts27CELLSStructureandFunctionCell=smallestunitoflifeCELLSStructureandFunction28FeaturesoftheHumanCell

ActinfilamentsNuclearEnvelopeCytoplasmIntermediatefilamentsMicrotubulesVesicleChromatinCentriolesCentrosomeLysosomeGolgiapparatusPolyribosomeMitochondrionRibosomesSmoothERRoughERNucleolusNucleusCytoskeletonEndoplasmic

ReticulumFeaturesoftheHumanCellAct29OrganizationoftheCellPlasmaMembrane

boundarysurroundingthecellGeneticmaterial:DNAlocatedinamembrane-boundnucleus

foreukaryoticcellsCytoplasmSemi-fluidmatrixcontainingenzymes

andorganelles

(enzyme=biologicalcatalyst)Cytoskeletonnetworkoffilamentsandtubulesincytoplasmthatmaintainscellshape,allowsmovementOrganizationoftheCellPlasm30FunctionsofCellFeatures

StructureFunction(s)PlasmaMembrane1.Regulatespassageofmaterialsintoandoutofcell2.Cell-CellRecognitionFunctionsofCellFeaturesSt31FunctionsofCellFeatures

StructureFunction(s)NucleusCarrierofgeneticmaterialDNA+protein=chromatin2.Governscellactivities3.DirectscellreproductionSurroundedbyMembrane=nuclearenvelopeContainsnucleolus—producesribosomesFunctionsofCellFeaturesSt32FunctionsofCellFeatures

StructureFunction(s)RibosomesSiteofproteinsynthesisCanbefreeincytoplasmorattachedtomembranesFunctionsofCellFeaturesSt33FunctionsofCellFeatures

StructureFunction(s)RoughEndoplasmicReticulum(RER)ProducesproteinsPreparesproteinsforexportSmoothEndoplasmicReticulum(SER)LipidSynthesisDrugdetoxificationTransportofproteinsfromRERRERSERFunctionsofCellFeaturesSt34FunctionsofCellFeaturesStructureFunction(s)GolgiApparatusCollects,modifies,packagesanddistributesproteinsandlipidsfromERFunctionsofCellFeaturesStr35FunctionsofCellFeatures

StructureFunction(s)LysosomeContainsdigestiveenzymestodigestfoodinprotistsordestroyagingorganellesFunctionsofCellFeaturesStr36EndomembraneSystemRough

Endoplasmic

ReticulumSmooth

Endoplasmic

ReticulumVesicleGolgi

ApparatusVesicleLysosomeVesiclePlasmaMembraneEndomembraneSystemRough

Endo37FunctionsofCellFeatures

StructureFunctionPeroxisomeRemovesharmfuloxidantsfromcellsFunctionsofCellFeaturesSt38FunctionsofCellFeatures

StructureFunctionMitochondrionCapturesenergyfromorganicmolecules,producingATPFunctionsofCellFeaturesSt39Functionsof

CellFeatures

StructureFunction(s)CytoskeletonMaintainscellshapeAnchorsorganellesandproteinsAllowsfororganellemovement

andcellularmovementinsomecelltypesFunctionsof

CellFeaturesS40FunctionsofCellFeaturesStructureFunctionCentrioleGivesrisetobasalbodiesthatproduceciliaorflagellaFunctionsofCellFeaturesStru41FunctionsofCellFeaturesStructureFunctionCentrosomeOrganizesmicrotubulesthatattachtochromosomesinnucleardivisionFunctionsofCellFeaturesStru42FunctionsofCellFeatures

StructureFunction(s)CiliaandFlagellaMovesubstancesacrosscellsurfaceinlungs,fallopiantubes

CellmovementinspermFunctionsofCellFeaturesSt43ConnectionsBetweenCells

TightJunction:joiningofproteins

createsimpermeablebarrierGapJunction:adjacentchannels

allowcommunicationAdhesionJunction:filamentsofcytoskeletonconnectcells,allowstretchConnectionsBetweenCellsTigh44FunctionsofPlasmaMembraneComponentsOutsideInsideplasmamembraneproteinsfilamentsofcytoskeletoncholesterolcarbohydratechainhydrophobictailsphopspholipidbilayerhydrophilicheadsRegulatesfluidityTransport,signalreception,recognitionCell-cellrecognitionControls

accessFunctionsofPlasmaMembraneC45Diffusion:MovementfromfromhighlowconcentrationtoreachequaldistributionmacromoleculeH2Oaquaporinproteinchargedmoleculesandionsunchargedmoleculesphospholipidmolecule+--+Freelydiffusethrough

phospholipidbilayerDiffusesthroughpores

inmembraneproteinsDiffusion:Movementfromfrom46Osmosis:DiffusionofWaterAcrossaSelectivelyPermeableMembraneIsotonicsolution

maintainscell

shapeCellsgainwaterina

Hypotonic(lowersalt)

solutionCellslosewaterina

Hypertonic(highersalt)solutionMembraneispermeabletowateronly,netmovementofwatertoinsideEqualmovementintoandoutofcellwhenequilibriumisreachedOsmosis:DiffusionofWaterAc47FacilitatedTransport:

UseofCarrierstoAssistwithDiffusionOutsideK+Na+Na+Insideglucosecarrier

proteinFacilitatedTransport:

Useof48ActiveTransportwithProteinCarrier:RequiresenergytotransportfromlowhighconcentrationInsideOutsideK+K+K+K+K+PNa+Na+Na+Na+Na+Na+Na+ATPADPActiveTransportwithProtein49TransportingLargeSubstancesEndocytosisExocytosisvesiclev

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