Decanoyl-L-carnitine-minus-Decanoylcarnitine-DataSheet-生命科学试剂-MedChemExpress

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEDecanoyl-L-carnitineCat.No.:HY-135035CASNo.:3992-45-8Synonyms:(-)-Decanoylcarnitine分⼦式:C₁₇H₃₃NO₄分⼦量:315.45作⽤靶点:Others作⽤通路:Others储存⽅式:Powder-20°C3years4°C2yearsInsolvent-80°C6months-20°C1month溶解性数据体外实验DMSO:100mg/mL(317.01mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制备储备液1mM3.1701mL15.8504mL31.7007mL5mM0.6340mL3.1701mL6.3401mL10mM0.3170mL1.5850mL3.1701mL请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。储备液的保存⽅式和期限：-80°C,6months;-20°C,1month。-80°C储存时，请在6个⽉内使⽤，-20°C储存时，请在1个⽉内使⽤。体内实验请根据您的实验动物和给药⽅式选择适当的溶解⽅案。以下溶解⽅案都请先按照InVitro⽅式配制澄的储备液，再依次添加助溶剂：(为保证实验结果的可靠性，澄的储备液可以根据储存条件，适当保存；体内实验的⼯作液，建议您现⽤现配，当天使⽤；以下溶剂前显⽰的百分⽐指该溶剂在您配制终溶液中的体积占⽐；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的⽅式助溶)1.请依序添加每种溶剂：10%DMSO>>40%PEG300>>5%Tween-80>>45%saline1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemESolubility:≥2.5mg/mL(7.93mM);Clearsolution2.请依序添加每种溶剂：10%DMSO>>90%(20%SBE-β-CDinsaline)Solubility:≥2.5mg/mL(7.93mM);Clearsolution3.请依序添加每种溶剂：10%DMSO>>90%cornoilSolubility:≥2.5mg/mL(7.93mM);ClearsolutionBIOLOGICALACTIVITY⽣物活性Decanoyl-L-carnitine对饱和脂酸代谢物的形成有促进作⽤。REFERENCES[1].TNTran,etal.Differencesintheconversionofthepolyunsaturatedfattyacids[1-(14)C]22:4(n-6)and[1-(14)C]22:5(n-3)to[(14)C]22:5(n-6)and[(14)C]22:6(n-3)inisolatedrathepatocytes.BiochimBiophysActa.2001May31;1532(1-2):137-47.[2].PatrickMCarry,etal.PhospholipidLevelsatSeroconversionAreAssociatedWithResolutionofPersistentIsletAutoimmunity:TheDiabetesAutoimmunityStudyintheYoung.DiabetesMcePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;02