腺鳞癌seer wclc1.数据库的数据分析

1、1. seer 数据库的腺鳞癌数据分析腺鳞癌的预后差的特点；腺鳞癌比例与预后的相关性研究*查文献；腺鳞癌 比例与淋转移的关系1.腺鳞癌基线特征肿瘤直径胸膜周围型/型 seer淋巴情况分化程度TNM 分期相关/非OS相关SUS纳入标准：行手术治疗的 单发的 病理确诊的2833 例1237 例有完整分期Primary Site（确认型或周围型）；完整病例资料者1. 摘要：低龄患者腺鳞癌相关风险预后分析-一项基于 SEER 数据库的研究背景：腺鳞癌为非小细胞肺癌中一种少见类型，约占 2%左右，其具有预后差特点。腺鳞癌中位发生为 岁，型与周围型腺鳞癌的淋转移情况及预后情况不明确。本研究拟通过分析不同区

2、域腺鳞癌的预后特点探索区域在腺鳞癌预后中的作用。方法：回顾性分析 SEER 数据 1973-2014 年行手术治疗的 单发的 病理确诊的 Primary Site（确认型或周围型）Histologic Type ICD-O-3 为 8560；完整病例资料者且有完整分期的 1237例腺鳞癌病例。排除合并其他肿瘤病史者，共纳入 1942 例。结果：2. 摘要 腺鳞癌比例及肿瘤大小与其淋转移的关系分析N0N1N2SexAge腺鳞癌比例3030-背景：腺鳞癌为非小细胞肺癌中一种少见类型，约占 2%左右。预后差特点。腺/鳞癌比例与淋转移及预后关系相对研究较少。方法：回顾性分析 2013-07-01 至

3、2017-06-01市肺科医院的行手术治疗的肺癌数据库。共纳入 67 例行手术切除术且具有明确/鳞癌比例的腺鳞癌病例。将/鳞癌比例分为 3组，即30%，30%-65%，65%；分别比较三组之间的纵隔淋率。转移情况，淋转移结果：其中病例 37 例，女例 30 例，右侧病例 42 例，左侧病例 25 例，型病例 9 例，周围型病例 58 例；中位为 63.19.1 岁；肿瘤平均直径为 3.82.1cm；淋巴结转移情况：共发生 N0 病例 43 例，N1 病例 9 例，N2 病例 15 例，其中淋转移成分为成分 23 例，占 95.8%；其中腺/鳞比例比例30%者 17 例，腺/鳞比例为 30%-6

4、5%者 18例，腺/鳞比例65%者 32 例。腺/鳞比例与淋转移情况相关性，统计学上无明显差异（p=0.148），右侧病变出现淋转移较左侧多见（p=0.030）.结论：腺鳞癌是一类好发于老年患者的恶性非小细胞肺癌，常见于周围型病变。其淋转移以成分为主，右侧病变可能淋转移发生率稍高，但腺/鳞比例与淋转移情况无明显相关性。Background: Adenosquamous carcinoma is a rare type of non-small cellg cancer, accountingfor about 2%. Poor prognosis. There is relatively li

5、ttle research on the relationship betratio of glandular/squamous cell carcinoma and lymph node metastasis and prognosis.n theMethods: A retrospectiveysis of theg cancer database of Shanghaig Hospital fromJuly 07 to 2017-06-01 was conducted. A total of 67 cases of adenosquamous carcinoma withsurgical

6、 resection and a clear ratio of adenocarcinoma/squamous carcinoma were included. Theo 3 groups, namely 30%,ratio of adenocarcinoma/squamous carcinoma was divided30%-65%, 65%; the mediastinal lymph node metastasis, lymph node metastasis rate werecompared among the three groups.Results: There were 37

7、male cases, 30 female cases, 42 right cases, 25 left cases, 9 central cases, and 58 peripheral cases. The median age was 63.19.1 years old. The average diameter of the tumor was 3.82.1cm; Lymph node metastasis: There were 43 cases of N0 cases, 9 cases of N1 cases, and 15 cases of N2 cases. The compo

8、nent in lymph node metastasis was 23 cases of adenocarcinoma, accounting for 95.8%; the ratio of adenocarcinoma/squamous in 17 cases was30%，adenocarcinoma/squamous ratio in 18 cases ranging from 30% to 65%, and 32 cases hadanadenocarcinoma/squamousratio65%.Thecorrelationbetntheratioofadenocarcinoma/

9、squamous and lymph node metastasis was sistically insignificant (p=0.148).Lymph node metastasis was more commonhe right lenhe left side (p=0.030).S: Adenosquamous carcinoma is a type of malignant non-small cellg cancertdevelops predominantly in elderly patients and is commonly seen in peripheral les. Thecomponent in lymph node metastasis was dominated by adenocarcinoma and the right lemay have a slightly higher incidence