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1、Medical TerminologyIntegumentary System-the skinObjectives1. Compare the epidermis, dermis, and subcutaneous tissue.2. Describe the roles of keratin and melanin in the skin.3. Name and describe the glands in the skin.4. Describe the structure of hair and of nails.5. Identify and use roots pertaining
2、 to the skin.6. Describe the main disorders that affect the skin.7. Label a diagram of the skin.8. Analyze several case studies involving the skin.Medical SpecialtyDermatology: branch of medicine concerned with diagnosis and treatment of diseases involving the skin and the relationship of skin lesio
3、ns to systemic diseases.Dermatologist: the physician who specializes in diagnosis and treatment of skin diseases.Cutaneous: pertaining to the skin (from Latin cutis, meaning “skin”)Anatomy of the SkinEpidermis - The outermost layer of the skin, 4 to 5 layers of epithelial cellsbasal layer or stratum
4、 basale : deepestHorny layer or stratum corneum: outermostKeratin : a protein that thickens and toughens the skin and makes up hair and nailsMelanin : a pigment that gives color to the skin and protects against sunlightDermis : the true skin or coriumconnective tissue, nerves, blood vessels, and lym
5、phaticsSubcutaneous tissue : beneath the skin; also called the hypodermisconnective tissue and fatAnatomy of the SkinAssociated Skin StructuresSudoriferous (sweat) glands :Sebaceous glands : a gland that produces sebum; usually associated with a hair follicle (root seb/o)Hair :hair follicleNails: An
6、atomy of the SkinStructure of the skin and subcutaneous tissueRoots Pertaining to the SkinTypes of Skin LesionsTypes of Skin LesionsKey Clinical TermsKey Clinical TermsSymptoms and ConditionsSymptoms and ConditionsSymptoms and ConditionsSymptoms and ConditionsSymptoms and ConditionsCase StudyCase St
7、udy(1)K.B., a 32-year-old fitness instructor, had noticed a “tiny hard lump” at the base of her left nostril while cleansing her face. The lesion had been present for about 2 months when she consulted a dermatologist. She had recently moved north from Florida, where she had worked as a lifeguard. Sh
8、e thought the lump might have been triggered by the regular tanning salon sessions she had used to retain her tan because it did not resemble the acne pustules, blackheads, or resulting scars of her adolescent years. Case Study(1)Although dermabrasion had removed the obvious acne scars and left seve
9、ral areas of dense skin, this lump was brown-pigmented and different. K.B. was afraid it might be a malignant melanoma. On examination, the dermatologist noted a small pearly-white nodule at the lower portion of the left ala (outer flared portion of the nostril). There were no other lesions on her f
10、ace or neckCase Study(1)A plastic surgeon excised the lesion and was able to re-approximate the wound edges without a fullthickness skin graft. The pathology report identified the lesion as a basal cell carcinoma with clean margins of normal skin and subcutaneous tissue and stated that the entire le
11、sion had been excised. K.B. was advised to wear SPF 30 sun protection on her face at all times and to avoid excessive sun exposure and tanning salons.Case Study(2)L.C., a 52-year-old female research chemist, has had a history of T-cell lymphoma for 8 years. She was initially treated with systemic ch
12、emotherapy with methotrexate until she contracted stomatitis. Continued therapy with topical chemotherapeutic agents brought some measurable improvement. She also had a history of hidradenitis.Case Study(2)A recent physical examination showed diffuse erythroderma with scaling and hyperkeratosis, plu
13、s alopecia. She had painful leukoplakia and ulcerations of the mouth and tongue. L.C. was hospitalized and given two courses of topical chemotherapy. She was referred to Dental Medicine for treatment of the oral lesions and discharged in stable condition with an appointment for follow-up in 4 weeks.
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